ChemicalBook >> CAS DataBase List >>3,4-dimethoxy-N-[4-(3-nitrophenyl)-1,3-thiazol-2-yl]benzenesulfonamide

3,4-dimethoxy-N-[4-(3-nitrophenyl)-1,3-thiazol-2-yl]benzenesulfonamide

3,4-dimethoxy-N-[4-(3-nitrophenyl)-1,3-thiazol-2-yl]benzenesulfonamide structure

CAS No.: 199666-03-0

Chemical Name:: 3,4-dimethoxy-N-[4-(3-nitrophenyl)-1,3-thiazol-2-yl]benzenesulfonamide

Synonyms: CS-1828;R061-8048;Ro 61-8048, >=98%;Ro 61-8048 >=98% (HPLC);KMO Inhibitor I, Ro 61-8048;KMO Inhibitor I, Ro 61-8048 - CAS 199666-03-0 - Calbiochem;3,4-Dimethoxy-N-4-(3-nitro-phenyl)-thiazol-2-yl-benzenesulfomide;3,4-diMethoxy-N-(4-(3-nitrophenyl)thiazol-2-yl)benzenesulfonaMide;3,4-Dimethoxy-N-[4-(3-nitrophenyl)-2-thiazolyl]benzenesulfonamide;Benzenesulfonamide, 3,4-dimethoxy-N-[4-(3-nitrophenyl)-2-thiazolyl]-

CBNumber:: CB61458468

Molecular Formula:: C17H15N3O6S2

Molecular Weight:: 421.45

MDL Number:: MFCD11040807

MOL File:: 199666-03-0.mol

MSDS File:: SDS

Last updated:2024-11-19 20:33:22

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3,4-dimethoxy-N-[4-(3-nitrophenyl)-1,3-thiazol-2-yl]benzenesulfonamide Properties

Melting point	185℃
Boiling point	627.4±65.0 °C(Predicted)
Density	1.471±0.06 g/cm3 (20 ºC 760 Torr)
storage temp.	2-8°C
solubility	DMSO: ≥15mg/mL
form	Yellow solid
pka	6.29±0.10(Predicted)
color	faint yellow to yellow

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H302-H319

Precautionary statements

P305+P351+P338

Hazard Codes

Risk Statements

25-36

Safety Statements

26-45

WGK Germany

NFPA 704

	0
2		0

3,4-dimethoxy-N-[4-(3-nitrophenyl)-1,3-thiazol-2-yl]benzenesulfonamide price More Price(23)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	SML0233	Ro 61-8048 ≥98% (HPLC)	199666-03-0	5mg	$132	2024-03-01	Buy
Sigma-Aldrich	420360-M	KMO Inhibitor I, Ro 61-8048	199666-03-0	10mg-m	$135	2021-12-16	Buy
Sigma-Aldrich	420360-M	KMO Inhibitor I, Ro 61-8048 - CAS 199666-03-0 - Calbiochem	199666-03-0	10mg	$135	2021-12-16	Buy
Cayman Chemical	15199	Ro 61-8048 ≥98%	199666-03-0	5mg	$81	2024-03-01	Buy
Cayman Chemical	15199	Ro 61-8048 ≥98%	199666-03-0	10mg	$112	2024-03-01	Buy

Product number	Packaging	Price	Buy
SML0233	5mg	$132	Buy
420360-M	10mg-m	$135	Buy
420360-M	10mg	$135	Buy
15199	5mg	$81	Buy
15199	10mg	$112	Buy

3,4-dimethoxy-N-[4-(3-nitrophenyl)-1,3-thiazol-2-yl]benzenesulfonamide Chemical Properties,Uses,Production

Uses

Ro 61-8048 is a potent and competitive kynurenine 3-monooxygenase (KMO) inhibitor.

Definition

ChEBI: Ro 61-8048 is a C-nitro compound.

Biological Activity

Potent and competitive kynurenine 3-hydroxylase inhibitor (K i = 4.8 nM, IC 50 = 37 nM). Increases kynurenic acid levels to concentrations that antagonize the glycine site of NMDA receptors. Brain penetrant and exhibits antidystonic, anticonvulsant and neuroprotective activities.

Biochem/physiol Actions

Ro 61-8048 is an inhibitor of kynurenine 3-monooxygenase (KMO) that increases kynurenic acid levels and reduces extracellular glutamate in the brain.

storage

+4°C

3,4-dimethoxy-N-[4-(3-nitrophenyl)-1,3-thiazol-2-yl]benzenesulfonamide Preparation Products And Raw materials

Raw materials

Preparation Products

3,4-dimethoxy-N-[4-(3-nitrophenyl)-1,3-thiazol-2-yl]benzenesulfonamide Suppliers

Global( 112)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Hangzhou FandaChem Co.,Ltd.	+8615858145714	FandaChem@Gmail.com	China	9206	55
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32957	60
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29881	58
BOC Sciences	+1-631-485-4226	inquiry@bocsci.com	United States	19553	58
Chengdu Feibo Pharm Technology Co., Ltd	+86 028-84641798 15982321820	abby@arkpharm.com	China	10924	58
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	32165	58
HANGZHOU CLAP TECHNOLOGY CO.,LTD	86-571-88216897,88216896 13588875226	sales@hzclap.com	CHINA	6312	58
Zhejiang J&C Biological Technology Co.,Limited	+1-2135480471 +1-2135480471	sales@sarms4muscle.com	China	10473	58
InvivoChem	+1-708-310-1919 +1-13798911105	sales@invivochem.cn	United States	6391	58
Coresyn Pharmatech Co., Ltd.	+86-571-86626709 +86-18157142896	cbc@coresyn.com	China	9984	58

Supplier	Advantage
Hangzhou FandaChem Co.,Ltd.	55
ATK CHEMICAL COMPANY LIMITED	60
career henan chemical co	58
BOC Sciences	58
Chengdu Feibo Pharm Technology Co., Ltd	58
TargetMol Chemicals Inc.	58
HANGZHOU CLAP TECHNOLOGY CO.,LTD	58
Zhejiang J&C Biological Technology Co.,Limited	58
InvivoChem	58
Coresyn Pharmatech Co., Ltd.	58

View Lastest Price from 3,4-dimethoxy-N-[4-(3-nitrophenyl)-1,3-thiazol-2-yl]benzenesulfonamide manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2024-11-19	Ro 61-8048 199666-03-0	US $33.00-70.00 / mg		99.91%	10g	TargetMol Chemicals Inc.
	2019-09-05	3,4-dimethoxy-N-[4-(3-nitrophenyl)-1,3-thiazol-2-yl]benzenesulfonamide 199666-03-0	US $1.00 / ASSAYS	1ASSAYS	98%	10kg	Career Henan Chemical Co

Ro 61-8048
199666-03-0
US $33.00-70.00 / mg
99.91%
TargetMol Chemicals Inc.

3,4-dimethoxy-N-[4-(3-nitrophenyl)-1,3-thiazol-2-yl]benzenesulfonamide
199666-03-0
US $1.00 / ASSAYS
98%
Career Henan Chemical Co

3,4-dimethoxy-N-[4-(3-nitrophenyl)-1,3-thiazol-2-yl]benzenesulfonamide Spectrum

3,4-dimethoxy-N-[4-(3-nitrophenyl)-1,3-thiazol-2-yl]benzenesulfonamide(199666-03-0)¹HNMR

199666-03-0(3,4-dimethoxy-N-[4-(3-nitrophenyl)-1,3-thiazol-2-yl]benzenesulfonamide)Related Search:

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ROC-325 RO2959 Hydrochloride

1of4

Ro 61-8048, >=98% RO61-80483,4-dimethoxy-N-(4-(3-nitrophenyl)thiazol-2-yl)Benzenesulfonamide 3,4-Dimethoxy-N-[4-(3-nitrophenyl)-2-thiazolyl]benzenesulfonamide RO61-8048 RO 61-8048 3,4-Dimethoxy-N-[4-(3-nitrophenyl)-2-thiazolyl]benzenesulfonamide KMO Inhibitor I, Ro 61-8048 3,4-dimethoxy-N-[4-(3-nitrophenyl)-1,3-thiazol-2-yl]benzenesulfonamide 3,4-Dimethoxy-N-[4-(3-nitrophenyl)-2-thiazolyl]benzenesulfonamide 3,4-diMethoxy-N-(4-(3-nitrophenyl)thiazol-2-yl)benzenesulfonaMide 3,4-Dimethoxy-N-4-(3-nitro-phenyl)-thiazol-2-yl-benzenesulfomide R061-8048 KMO Inhibitor I, Ro 61-8048 - CAS 199666-03-0 - Calbiochem CS-1828 Benzenesulfonamide, 3,4-dimethoxy-N-[4-(3-nitrophenyl)-2-thiazolyl]- Ro 61-8048 >=98% (HPLC) NMDA,Ro 61 8048,inhibit,Ro 61-8048,dystonia,Inhibitor,hydroxylase,Ro 618048,kynurenine 3,4-dimethoxy 3,4-dimethoxy-N-[4-(3-nitrophenyl)-1,3-thiazol-2-yl]benzenesulfonamide 199666-03-0 C17H15N3O6S2 Inhibitors