Albiglutide
- CAS No.
- 782500-75-8
- Chemical Name:
- Albiglutide
- Synonyms
- Albugon;Gsk 716155;albiglutide;Naliglutide;Unii-5E7U48495e;Albiglutide Fragment;Albiglutide(Acetate);Albiglutide USP/EP/BP;Research Grade Albiglutide;Albiglutide Eperzan Tanzeum
- CBNumber:
- CB61518490
- Molecular Formula:
- C148H223N39O46
- Molecular Weight:
- 3284.58792
- MDL Number:
- MFCD27976663
- MOL File:
- 782500-75-8.mol
storage temp. | Store at -20°C |
---|---|
Water Solubility | Water: 100 mg/mL (30.45 mM); |
InChIKey | OGWAVGNOAMXIIM-VTAHJYCESA-N |
FDA UNII | 5E7U48495E |
ATC code | A10BJ04 |
Albiglutide price
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
American Custom Chemicals Corporation | API0024526 | ALBIGLUTIDE 95.00% | 782500-75-8 | 5MG | $502.4 | 2021-12-16 | Buy |
Biorbyt Ltd | orb573360 | Albiglutide >98% | 782500-75-8 | 100mg | $1431.4 | 2021-12-16 | Buy |
Biorbyt Ltd | orb573360 | Albiglutide >98% | 782500-75-8 | 250mg | $2839 | 2021-12-16 | Buy |
Biorbyt Ltd | orb573360 | Albiglutide >98% | 782500-75-8 | 1g | $5654.2 | 2021-12-16 | Buy |
DC Chemicals | DC20174 | Albiglutide >98% | 782500-75-8 | 1g | $3800 | 2021-12-16 | Buy |
Albiglutide Chemical Properties,Uses,Production
General Description
Albiglutide (also known as naliglutide, GSK 716155) isa sequential dimer of GLP-1(7–36)(Ala8→Gly) covalentlylinked to modified human serum albumin (i.e., it is a “fusionprotein” with modified HSA). This molecule is currentlywell into phase III clinical trials. Although albiglutide,if marketed (Syncria, GlaxoSmithKline), will—likeexenatide—be administered by injection, the half-life andduration of 6 to 7 days would allow for weekly administration.
Clinical Use
GLP-1 receptor agonist:
Treatment of type 2 diabetes mellitus
Enzyme inhibitor
This GLP-1 agonist and anti-diabetic drug (MW = 72.9 kDa; CAS 782500- 75-8), marketed as Eperzan? and Tanzeum?, by GlaxoSmithKline (GSK) is a dipeptidyl peptidase-4-resistant glucagon-like peptide-1 dimer fused to human albumin. Albiglutide has a half-life of 4-7 days, commending it for biweekly or weekly administration in the treatment of Type 2 diabetes. The half-life is considerably longer than exenatide (Byetta?) and liraglutide (Victoza?).
Metabolism
Albiglutide is a protein for which the expected metabolic pathway is degradation to small peptides and individual amino acids by ubiquitous proteolytic enzymes.
Albiglutide Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Zibo Hangyu Biotechnology Development Co., Ltd | +86-0533-2185556 +8617865335152 | Mandy@hangyubiotech.com | China | 10986 | 58 |
Nantong Guangyuan Chemicl Co,Ltd | +undefined17712220823 | admin@guyunchem.com | China | 615 | 58 |
Shandong Huizhihan Supply Chain Co., Ltd | +86-13363081709 +86-13363081709 | 3957328362@qq.com | China | 170 | 58 |
career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29886 | 58 |
Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 | admin@nexconn.com | China | 10310 | 58 |
Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28172 | 58 |
Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22963 | 58 |
BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19553 | 58 |
Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | sales@chemdad.com | China | 39894 | 58 |
Hebei shuoxi biotechnology co. LTD | +8613081092107 | CHINA | 964 | 58 |
View Lastest Price from Albiglutide manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2024-11-02 | Albiglutide
782500-75-8
|
US $0.00 / mg | 1mg | ≥95% or 98% | 1kg/month | WUHAN FORTUNA CHEMICAL CO., LTD | ||
2024-10-31 | Albiglutide Eperzan Tanzeum
782500-75-8
|
US $0.00-0.00 / box | 1box | 99% | 2000 | Shandong Huizhihan Supply Chain Co., Ltd | ||
2024-08-27 | Albiglutide
782500-75-8
|
US $95.00-950.00 / kg | 10kg | 0.99 | 20tons | Zibo Hangyu Biotechnology Development Co., Ltd |
- Albiglutide
782500-75-8
- US $0.00 / mg
- ≥95% or 98%
- WUHAN FORTUNA CHEMICAL CO., LTD
- Albiglutide Eperzan Tanzeum
782500-75-8
- US $0.00-0.00 / box
- 99%
- Shandong Huizhihan Supply Chain Co., Ltd
- Albiglutide
782500-75-8
- US $95.00-950.00 / kg
- 0.99
- Zibo Hangyu Biotechnology Development Co., Ltd