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Bis(2-oxo-3-oxazolidinyl)phosphinic chloride

CAS No.
68641-49-6
Chemical Name:
Bis(2-oxo-3-oxazolidinyl)phosphinic chloride
Synonyms
BOP-CL;BOP-CI;BOP-C;BOPDC;idinyL;BIS(2-OXO-3-OX;Phosphoric acid bi;Bis(2-oxo-3-oxazoL;Bis(2-oxo-3-oxazolid;bis(2-oxo-3-oxazolidinyl)-phosphinicchlorid
CBNumber:
CB6177768
Molecular Formula:
C6H8ClN2O5P
Molecular Weight:
254.56
MDL Number:
MFCD00010077
MOL File:
68641-49-6.mol
MSDS File:
SDS
Last updated:2024-12-25 15:20:59

Bis(2-oxo-3-oxazolidinyl)phosphinic chloride Properties

Melting point 191 °C (dec.)(lit.)
Boiling point 332.8±25.0 °C(Predicted)
Density 1.71±0.1 g/cm3(Predicted)
storage temp. Inert atmosphere,Room Temperature
solubility slightly sol CH2Cl2, MeCN, THF, DMF; dec H2O
form Crystalline Powder
pka -2.47±0.20(Predicted)
color White to off-white
Water Solubility Hydrolyzes with water.
Sensitive Moisture Sensitive
BRN 3654596
InChIKey KLDLRDSRCMJKGM-UHFFFAOYSA-N
CAS DataBase Reference 68641-49-6(CAS DataBase Reference)
FDA UNII V974K6W8Y7

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS05
Signal word  Danger
Hazard statements  H314
Precautionary statements  P260-P280-P303+P361+P353-P304+P340+P310-P305+P351+P338-P363
Hazard Codes  C
Risk Statements  34
Safety Statements  26-36/37/39-45-27
RIDADR  UN 3261 8/PG 2
WGK Germany  3
RTECS  SZ5871000
10-21
HazardClass  8
PackingGroup  II
HS Code  29349990
NFPA 704
0
3 0

Bis(2-oxo-3-oxazolidinyl)phosphinic chloride price More Price(32)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 15140 Bis(2-oxo-3-oxazolidinyl)phosphinic chloride ≥97.0% (AT) 68641-49-6 5g $90.8 2024-03-01 Buy
Sigma-Aldrich 15140 Bis(2-oxo-3-oxazolidinyl)phosphinic chloride ≥97.0% (AT) 68641-49-6 25g $355 2024-03-01 Buy
TCI Chemical B1213 Bis(2-oxo-3-oxazolidinyl)phosphinic Chloride >97.0%(T) 68641-49-6 5g $25 2024-03-01 Buy
TCI Chemical B1213 Bis(2-oxo-3-oxazolidinyl)phosphinic Chloride >97.0%(T) 68641-49-6 25g $84 2024-03-01 Buy
Alfa Aesar L08775 Bis(2-oxo-3-oxazolidinyl)phosphinic chloride, 97% 68641-49-6 5g $51.65 2024-03-01 Buy
Product number Packaging Price Buy
15140 5g $90.8 Buy
15140 25g $355 Buy
B1213 5g $25 Buy
B1213 25g $84 Buy
L08775 5g $51.65 Buy

Bis(2-oxo-3-oxazolidinyl)phosphinic chloride Chemical Properties,Uses,Production

Description

Bis(2-oxo-3-oxazolidinyl)phosphinic chloride is a reagent for activating carboxyl groups, converting acids to esters (including thioesters and phosphoesters), amides (including peptides and β-lactams), and anhydrides; reagent for kinetic resolution of racemic carboxylic acids and alcohols.

Chemical Properties

White solid

Uses

Bis(2-oxo-3-oxazolidinyl)phosphinic chloride was used in the preparation of hexadepsipeptide.

storage

Bis(2-oxo-3-oxazolidinyl)phosphinic chloride should store in a cool dry place under nitrogen to preclude contact with moisture  and oxygen. Use only in a chemical fume hood. Wear suitable protective clothing and eye/face protection.  Causes burns and is harmful if swallowed, inhaled, or absorbed through skin.

Purification Methods

the outcome of reactions can be greatly affected by the purity of the reagent; commercial samples may require to be washed with cold water and recrystallized from MeCN prior to use.

497-25-6
68641-49-6
Synthesis of Bis(2-oxo-3-oxazolidinyl)phosphinic chloride from 2-Oxazolidone

Bis(2-oxo-3-oxazolidinyl)phosphinic chloride Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 270)Suppliers
Supplier Tel Email Country ProdList Advantage
Capot Chemical Co.,Ltd.
+86-(0)57185586718 +86-13336195806 sales@capot.com China 29791 60
Shanghai Daken Advanced Materials Co.,Ltd
+86-371-66670886 info@dakenam.com China 18751 58
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795 ivan@atkchemical.com China 32956 60
AB PharmaTech,LLC
323-480-4688 sales@acrospharmatech.com United States 989 55
Shanghai Zheyan Biotech Co., Ltd.
18017610038 zheyansh@163.com CHINA 3619 58
career henan chemical co
+86-0371-86658258 +8613203830695 sales@coreychem.com China 29880 58
SHANDONG ZHI SHANG CHEMICAL CO.LTD
+86 18953170293 sales@sdzschem.com China 2930 58
Shenzhen Nexconn Pharmatechs Ltd
+86-755-89396905 +86-15013857715 admin@nexconn.com China 10311 58
Xiamen AmoyChem Co., Ltd
+86-86-5926051114 +8618959220845 sales@amoychem.com China 6383 58
Hubei xin bonus chemical co. LTD
86-13657291602 linda@hubeijusheng.com CHINA 22963 58

View Lastest Price from Bis(2-oxo-3-oxazolidinyl)phosphinic chloride manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Bis(2-oxo-3-oxazolidinyl)phosphinic chloride pictures 2024-12-13 Bis(2-oxo-3-oxazolidinyl)phosphinic chloride
68641-49-6
US $0.00 / G 100G 98%min 30kg/month WUHAN FORTUNA CHEMICAL CO., LTD
Bis(2-oxo-3-oxazolidinyl)phosphinic chloride pictures 2022-09-27 Bis(2-oxo-3-oxazolidinyl)phosphinic chloride
68641-49-6
US $0.00-0.00 / KG 1KG 98% 1ton Henan Aochuang Chemical Co.,Ltd.
Bis(2-oxo-3-oxazolidinyl)phosphinic chloride pictures 2021-07-13 Bis(2-oxo-3-oxazolidinyl)phosphinic chloride
68641-49-6
US $15.00-10.00 / KG 1KG 99%+ HPLC Monthly supply of 1 ton Zhuozhou Wenxi import and Export Co., Ltd
bis(2-oxo-3-oxazolidinyl)-phosphinicchlorid PHOSPHORIC ACID BIS(2-OXOOXAZOLIDIDE) CHLORIDE N,N-BIS(2-OXO-3-OXAZOLIDINYL)PHOSPHINIC CHLORIDE N,N-BIS(2-OXO-3-OXAZOLIDINYL)PHOSPHONIC CHLORIDE N,N-BIS(2-OXO-3-OXAZOLIDINYL)PHOSPHORODIAMIDIC CHLORIDE Bis(2-oxo-3-oxazolid Phosphoric acid bi Phosphoric acid bis(2-oxooxazolidide) chloride(BOP-Cl) Bis(2-oxo-1,3-oxazolidin-3-yl)phosphinic chloride N,N-Bis(2-oxo-3-oxazolidinyl)phosphinic chloride≥ 98% (Assay) Bis(2-oxooxazolidin-3-yl)phosphinic chloride Double(2-oxo -3-oxazolaM)phosphinic chloride Bis(2-oxo-3-oxazolidinyl)phosphinic chloride >=97.0% (AT) BOP-Cl Bis(2-oxo-3-oxazolidinyl)phosphonic chloride Bis(2-oxo-3-oxazolidinyl)phosphinic chloride, 97% 5GR BIS(2-OXO-3-OXAZOLIDINYL)PHOSPHINIC CHLORIDE BIS(2-OXO-3-OXAZOLIDINYL)PHOSPHONIC CHLORIDE BIS(2-OXO-3-OXAZOLIDINYL)PHOSPHORODIAMIDIC CHLORIDE BIS(2-OXO-3-OXAZOLIDINYL)PHOSPHINIC CHLORIDE (BOP-CL) N,N-BIS(2-OXO-3-OXAZOLIDINYL)PHOSPHORAMIDIC CHLORIDE BOP-CL BIS(2-OXO-3-OXAZOLIDINYL)PHOSPHINIC CHLORIDE Bis-(2-oxo-3-oxazolidinyl)-phosphinyl chloride 3,3'-(Chlorophosphinylidene)bis(oxazolidine-2-one) 3,3'-(Chlorophosphonoyl)bis(oxazolidine-2-one) 3,3'-(Oxochlorophosphoranylidene)bis(oxazolidine-2-one) 3,3'-Chlorophosphinylidenebis(oxazolidine-2-one) Bis(2-oxo-3-oxazolidinyl)chlorophosphine oxide Bis(2-oxo-3-oxazolidinyl)phosphinic acidchloride BOP-Cl, Phosphoric acid bis(2-oxooxazolidide) chloride 3-[Chloro-(2-oxo-1,3-oxazolidin-3-yl)phosphoryl]-1,3-oxazolidin-2-one BOP-C BOPDC Bis(2-oxo-3-oxazolidinyl)phosphinic chloride ,97% BIS(2-OXO-3-OX Phosphinic chloride,P,P-bis(2-oxo-3-oxazolidinyl)- Bis(2-oxo-3-oxazolidinyl)phosphinic chloride, 97%, for synthesis Bis(2-oxo-3-oxazolidinyl)phosphinic Chloride > Bis(2-oxo-3-oxazoL idinyL Bis(2-oxo-3-oxazolidinyl)phosphinic chloride USP/EP/BP BOP-CI BOP-CL 3-[chloro-(2-oxooxazolidin-3-yl)phosphoryl]oxazolidin-2-one 68641-49-6 C8H8ClN2O5P C6H8ClN2O5P Building Blocks Heterocyclic Building Blocks Oxazolines/Oxazolidines Coupling Reactions (Peptide Synthesis) Peptide Synthesis Condensation & Active Esterification Coupling Reagent Peptide coupling agents Biochemistry Condensation & Active Esterification Coupling Reactions (Peptide Synthesis) Peptide Synthesis