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PARAOXON

CAS No.
311-45-5
Chemical Name:
PARAOXON
Synonyms
E 600;PS610;ts219;ETICOL;PS-610;hc2072;Ts 219;HC 2072;Mintaco;Paroxan
CBNumber:
CB2463711
Molecular Formula:
C10H14NO6P
Molecular Weight:
275.2
MDL Number:
MFCD00007316
MOL File:
311-45-5.mol
MSDS File:
SDS
Last updated:2023-05-15 10:43:30

PARAOXON Properties

Melting point 300°C
Boiling point 169-170°C
Density 1.274 g/mL at 25 °C(lit.)
refractive index n20/D 1.51(lit.)
storage temp. 2-8°C
solubility Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
form oil
color yellow
Odor slt odor
Water Solubility 3.627g/L(20 ºC)
Merck 13,7102
BRN 1915526
Stability Moisture Sensitive
CAS DataBase Reference 311-45-5
EWG's Food Scores 1-3
FDA UNII Q9CX8P80JW
ATC code S01EB10
EPA Substance Registry System Paraoxon (311-45-5)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictograms
GHS06,GHS09
Signal word  Danger
Hazard statements  H300+H310-H410
Precautionary statements  P262-P273-P280-P301+P310+P330-P302+P352+P310
Hazard Codes  T+,N
Risk Statements  26/27/28-50
Safety Statements  36/37/39-45-61
RIDADR  UN 2810 6.1/PG 1
WGK Germany  3
RTECS  TC2275000
HazardClass  6.1(a)
PackingGroup  I
Toxicity LD50 orally in rats: 1.8 mg/kg (Pickering, Malone)

PARAOXON Chemical Properties,Uses,Production

Chemical Properties

Oily Liquid

Chemical Properties

Paraoxon is an odorless, reddish-yellow oil. Fruity odor.

Uses

A cholinesterase inhibitor

Uses

Paraoxon-ethyl has been used as a substrate?in paraoxonase (PON) activity assay. It has also been used as a lipase inhibitor to study the effects of anacetrapib on homotypic transfer from high density lipoprotein?L3 (HDL3)?to?HDL2?in vivo.

Uses

Insecticide.

Definition

ChEBI: An aryl dialkyl phosphate where both the alkyl groups are ethyl and the aryl group is 4-nitrophenyl.

Synthesis Reference(s)

Tetrahedron Letters, 31, p. 3359, 1990 DOI: 10.1016/S0040-4039(00)89065-6

General Description

Reddish-yellow oily liquid with a faint fruity odor.

Reactivity Profile

Organophosphates are susceptible to formation of highly toxic and flammable phosphine gas in the presence of strong reducing agents such as hydrides. Partial oxidation by oxidizing agents may result in the release of toxic phosphorus oxides.

Fire Hazard

Flash point data for PARAOXON are not available; however, PARAOXON is probably combustible.

Biochem/physiol Actions

Potent irreversible acetylcholinesterase inhibitor

Safety Profile

A deadly poison by ingestion,intraperitoneal, intravenous, subcutaneous, intramuscular,and parenteral routes. Mutation data reported. Humansystemic effects: coma, convulsions, miosis. Acholinesterase inhibitor. An insecticide. When heated todecompos

Potential Exposure

An organophosphate insecticide. Has been used as a medication.

Shipping

UN3018 Organophosphorus pesticides, liquid, toxic, Hazard Class: 6.1; Labels: 6.1-Poisonous materials.

Incompatibilities

Keep away from alkaline materials and strong oxidizers. Contact with oxidizers can cause the release of toxic oxides of phosphorus. May react violently with antimony(V) pentafluoride. Incompatible with lead diacetate, magnesium, silver nitrate. In the presence of strong reducing agents such as hydrides, organophosphates form highly toxic and flammable phosphine gas.

Waste Disposal

In accordance with 40CFR165, follow recommendations for the disposal of pesticides and pesticide containers. Must be disposed properly by following package label directions or by contacting your local or federal environmental control agency, or by contacting your regional EPA office.

PARAOXON Preparation Products And Raw materials

DIETHYL P-NITROPHENYL PHOSPHATE E 600 ESTER 25 FOSFAKOL ETICOL Chinorta Chinorto Diaethyl-p-nitrophenylphosphorsaeureester Diethyl paraoxon diethyl4-nitrophenylphosphate diethylparaoxon Diethyl-p-nitrofenyl ester kyseliny fosforecne Diethyl p-nitrophenyl phosphate, Paraoxon-ethyl O,O-Diethyl O-(4-nitrophenyl) phosphate, Diethyl p-nitrophenyl phosphate, Paraoxon-ethyl Paraoxon-ethyl,O,O-Diethyl O-(4-nitrophenyl) phosphate, Diethyl p-nitrophenyl phosphate, Paraoxon-ethyl 4-Nitrophenyl diethyl phosphate NSC 404110 Paraoxon-ethy PS610 PS-610 Paraoxon-ethyl Solution, 100ppm diethyl-p-nitrofenylesterkyselinyfosforecne diethyl-p-nitrofenylesterkyselinyfosforecne(czech) Diethylp-nitrophenylphospha E 600 (Pesticide) e600(pesticide) ENT 16,087 ent16,087 Ethyl Paraoxan Ethyl paraoxon Ethyl p-nitrophenyl ethylphosphate ethylparaoxon ethylp-nitrophenylethylphosphate HC 2072 hc2072 Mintaco mintisal Miotisal o,o’-diaethyl-p-nitrophenylphosphat o,o’diaethyl-p-nitrophenylphosphat O,O'Diaethyl-p-nitrophenylphosphat O,O-Diethyl O-p-nitrophenyl phosphate o,o-diethylo-p-nitrophenylphosphate O,O-Dietyl-O-p-nitrofenylfosfat o,o-dietyl-o-p-nitrofenylfosfat(czech) Oxyparathion Paraoxone Parathion ethyl oxon Parathion O-analog Parathion oxon Paroxan Pestox 101 pestox101 Phenol, p-nitro-, ester with diethyl phosphate Phosphachole Phosphakol Phosphonothioic acid, diethylparanitrophenyl ester phosphonothioicacid,diethylparanitrophenylester