ChemicalBook >> CAS DataBase List >>8-[4-[((4-Cyanophenyl)carbamoylmethyl)oxy]phenyl]-1,3-di(n-propyl)xanthine hydrate
8-[4-[((4-Cyanophenyl)carbamoylmethyl)oxy]phenyl]-1,3-di(n-propyl)xanthine hydrate
![8-[4-[((4-Cyanophenyl)carbamoylmethyl)oxy]phenyl]-1,3-di(n-propyl)xanthine hydrate Structure](CAS/GIF/264622-58-4.gif)
- CAS No.
- 264622-58-4
- Chemical Name:
- 8-[4-[((4-Cyanophenyl)carbamoylmethyl)oxy]phenyl]-1,3-di(n-propyl)xanthine hydrate
- Synonyms
- MRS 1754 hydrate;MRS1754;MRS-1754;MRS 1754;Adenosine Receptor,MRS-1754,Inhibitor,MRS 1754,P1 receptor,MRS1754,inhibit;N-(4-cyanophenyl)-2-[4-(2,6-dioxo-1,3-dipropyl-7H-purin-8-yl)phenoxy]acetamide;8-[4-[((4-Cyanophenyl)carbamoylmethyl)oxy]phenyl]-1,3-di(n-propyl)xanthine hydrate;N-(4-cyanophenyl)-2-[4-(2,6-dioxo-1,3-dipropyl-2,3,6,7-tetrahydro-1H-purin-8-yl)phenoxy]acetaMide;N-(4-Cyanophenyl)-2-(4-(2,6-dioxo-1,3-dipropyl-2,3,6,9-tetrahydro-1H-purin-8-yl)phenoxy)acetamide;AcetaMide,N-(4-cyanophenyl)-2-[4-(2,3,6,9-tetrahydro-2,6-dioxo-1,3-dipropyl-1H-purin-8-yl)phenoxy]-;AcetaMide, N-(4-cyanophenyl)-2-[4-(2,3,6,7-tetrahydro-2,6-dioxo-1,3-dipropyl-1H-purin-8-yl)phenoxy]-
- CBNumber:
- CB62098696
- Molecular Formula:
- C26H26N6O4
- Molecular Weight:
- 486.52
- MDL Number:
- MFCD09971130
- MOL File:
- 264622-58-4.mol
- MSDS File:
- SDS
Last updated:2024-11-19 23:02:33
| Density | 1.38±0.1 g/cm3(Predicted) |
|---|---|
| storage temp. | room temp |
| solubility | DMSO: soluble >10mg/mL |
| pka | 8.24±0.70(Predicted) |
| form | solid |
| color | off-white |
| FDA UNII | 7E435V2DAH |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS05 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H314-H290 | |||||||||
| Precautionary statements | P501-P260-P234-P264-P280-P390-P303+P361+P353-P301+P330+P331-P363-P304+P340+P310-P305+P351+P338+P310-P406-P405 | |||||||||
| Safety Statements | 22-24/25 | |||||||||
| WGK Germany | 3 | |||||||||
| NFPA 704 |
|
8-[4-[((4-Cyanophenyl)carbamoylmethyl)oxy]phenyl]-1,3-di(n-propyl)xanthine hydrate price More Price(14)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | M6316 | MRS 1754 hydrate ≥98% (HPLC), solid | 264622-58-4 | 5mg | $265 | 2024-03-01 | Buy |
| Sigma-Aldrich | M6316 | MRS 1754 hydrate ≥98% (HPLC), solid | 264622-58-4 | 25mg | $837 | 2024-03-01 | Buy |
| TRC | M750243 | MRS1754 | 264622-58-4 | 1mg | $115 | 2021-12-16 | Buy |
| ChemScene | CS-0003210 | MRS1754 98.31% | 264622-58-4 | 5mg | $140 | 2021-12-16 | Buy |
| ChemScene | CS-0003210 | MRS1754 98.31% | 264622-58-4 | 10mg | $190 | 2021-12-16 | Buy |
8-[4-[((4-Cyanophenyl)carbamoylmethyl)oxy]phenyl]-1,3-di(n-propyl)xanthine hydrate Chemical Properties,Uses,Production
Uses
MRS 1754 acts as an adenosine receptor antagonist which displays bronchospasmolytic activity, applicable to treatments involving respiratory disorders.
Definition
ChEBI: N-(4-cyanophenyl)-2-[4-(2,6-dioxo-1,3-dipropyl-7H-purin-8-yl)phenoxy]acetamide is an oxopurine.
Biological Activity
Selective adenosine A 2B receptor antagonist (K i values are 1.97, 16.8, 403, 503, 570 and 612 nM for hA 2B , rA 1 , hA 1 , hA 2A , hA 3 and rA 2A receptors respectively).
Biochem/physiol Actions
MRS 1754 hydrate is a p-cyanoanilide xanthine derivative. It might act as a potential anti-asthmatic drug.
storage
Desiccate at RT
8-[4-[((4-Cyanophenyl)carbamoylmethyl)oxy]phenyl]-1,3-di(n-propyl)xanthine hydrate Preparation Products And Raw materials
Raw materials
Preparation Products
8-[4-[((4-Cyanophenyl)carbamoylmethyl)oxy]phenyl]-1,3-di(n-propyl)xanthine hydrate Suppliers
Global( 41)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32165 | 58 |
| LEAP CHEM CO., LTD. | +86-852-30606658 | market18@leapchem.com | China | 24727 | 58 |
| Hangzhou MolCore BioPharmatech Co.,Ltd. | +86-057181025280; +8617767106207 | sales@molcore.com | China | 49734 | 58 |
| Wuhan Topule Biopharmaceutical Co., Ltd | +8618327326525 | masar@topule.com | China | 8467 | 58 |
| Aladdin Scientific | +1-+1(833)-552-7181 | sales@aladdinsci.com | United States | 57505 | 58 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 821-50328103-801 18930552037 | 3bsc@sina.com | China | 15839 | 69 |
| Chembest Research Laboratories Limited | +86-21-20908456 | sales@BioChemBest.com | China | 6005 | 61 |
| Hangzhou Sage Chemical Co., Ltd. | +86057186818502 13588463833 | info@sagechem.com | China | 10266 | 58 |
| Shanghai Topbiochem Technology Co., Ltd | 021-58170097 | info@topbiochem.com | China | 9459 | 58 |
| EMMX Biotechnology LLC | 888-539-0666 | info@emmx.com | United States | 8447 | 60 |
View Lastest Price from 8-[4-[((4-Cyanophenyl)carbamoylmethyl)oxy]phenyl]-1,3-di(n-propyl)xanthine hydrate manufacturers
264622-58-4(8-[4-[((4-Cyanophenyl)carbamoylmethyl)oxy]phenyl]-1,3-di(n-propyl)xanthine hydrate)Related Search:
8-[4-[((4-Cyanophenyl)carbamoylmethyl)oxy]phenyl]-1,3-di(n-propyl)xanthine hydrate
MRS 1754 hydrate
AcetaMide, N-(4-cyanophenyl)-2-[4-(2,3,6,7-tetrahydro-2,6-dioxo-1,3-dipropyl-1H-purin-8-yl)phenoxy]-
N-(4-cyanophenyl)-2-[4-(2,6-dioxo-1,3-dipropyl-2,3,6,7-tetrahydro-1H-purin-8-yl)phenoxy]acetaMide
AcetaMide,N-(4-cyanophenyl)-2-[4-(2,3,6,9-tetrahydro-2,6-dioxo-1,3-dipropyl-1H-purin-8-yl)phenoxy]-
N-(4-Cyanophenyl)-2-(4-(2,6-dioxo-1,3-dipropyl-2,3,6,9-tetrahydro-1H-purin-8-yl)phenoxy)acetamide
N-(4-cyanophenyl)-2-[4-(2,6-dioxo-1,3-dipropyl-7H-purin-8-yl)phenoxy]acetamide
MRS1754;MRS-1754;MRS 1754
Adenosine Receptor,MRS-1754,Inhibitor,MRS 1754,P1 receptor,MRS1754,inhibit
264622-58-4