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6-ISOPROPOXY-9-XANTHONE-2-CARBOXYLIC ACID

CAS No.
33458-93-4
Chemical Name:
6-ISOPROPOXY-9-XANTHONE-2-CARBOXYLIC ACID
Synonyms
AH 6809;AH6809;AH-6809;6-ISOPROPOXY-9-XANTHONE-2-CARBOXYLIC ACID;6-ISOPROPOXY-9-OXOXANTHENE-2-CARBOXYLIC ACID;6-Isopropoxy-9-oxo-9H-xanthene-2-carboxylic acid;6-(1-Methylethoxy)-9-oxo-9H-xanthene-2-carboxylic acid;9-oxo-6-(propan-2-yloxy)-9H-xanthene-2-carboxylic acid;9H-Xanthene-2-carboxylic acid, 6-(1-methylethoxy)-9-oxo-;Prostaglandin Receptor,AH-6809,inhibit,Inhibitor,AH6809,AH 6809
CBNumber:
CB6209962
Molecular Formula:
C17H14O5
Molecular Weight:
298.29
MDL Number:
MFCD08056083
MOL File:
33458-93-4.mol
MSDS File:
SDS
Last updated:2024-11-19 23:02:33

6-ISOPROPOXY-9-XANTHONE-2-CARBOXYLIC ACID Properties

storage temp. Sealed in dry,Room Temperature
solubility ethanol: 2.5 mg/mL, soluble
form crystalline solid or supercooled liquid
color White
Stability Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 6 months.

SAFETY

Risk and Safety Statements

WGK Germany  3

6-ISOPROPOXY-9-XANTHONE-2-CARBOXYLIC ACID price More Price(33)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich A1221 AH6809 ≥98%, crystalline solid or supercooled liquid 33458-93-4 5mg $66 2024-03-01 Buy
Cayman Chemical 14050 AH 6809 ≥98% 33458-93-4 1mg $19 2024-03-01 Buy
Cayman Chemical 14050 AH 6809 ≥98% 33458-93-4 5mg $78 2024-03-01 Buy
Cayman Chemical 14050 AH 6809 ≥98% 33458-93-4 10mg $138 2024-03-01 Buy
Cayman Chemical 14050 AH 6809 ≥98% 33458-93-4 50mg $595 2024-03-01 Buy
Product number Packaging Price Buy
A1221 5mg $66 Buy
14050 1mg $19 Buy
14050 5mg $78 Buy
14050 10mg $138 Buy
14050 50mg $595 Buy

6-ISOPROPOXY-9-XANTHONE-2-CARBOXYLIC ACID Chemical Properties,Uses,Production

Description

AH 6809 is an EP and DP receptor antagonist with nearly equal affinity for the cloned human EP1, EP2, EP3-III, and DP1 receptors. AH 6809 blocks the PGE2-induced accumulation of cAMP in COS cells transfected with the human EP2 receptor. It also blocks the accumulation of Ca2+ in Xenopus oocytes expressing the human EP1 receptor. In the human and guinea pig, the activity profile of AH 6809 is similar to that of SC-19220, but it is somewhat more potent. In the mouse, AH 6809 has the highest affinity for the EP2 receptor, but also acts as a weak ligand at the murine EP1 and DP1 receptors. In whole human platelets, AH 6809 is an effective antagonist of the antiaggregatory actions of PGD2, but not PGI2, with an EC50 of about 5 x 10−5 M.

Uses

AH-6809 is a prostaglandin E2 receptor antagonist.

Definition

ChEBI: 9-oxo-6-propan-2-yloxy-2-xanthenecarboxylic acid is a member of xanthones.

Biological Activity

Antagonist at prostaglandin EP 1 (pA 2 = 6.8 ) and EP 2 (K i = 350 nM) receptors. Also weakly inhibits DP receptors (pA 2 = 4.45).

storage

Store at RT

References

1) Coleman in Prostaglandins and Related Substances: A Practical Approach; ILR Press, Oxford and Washington D.C. 1987, pg 267

6-ISOPROPOXY-9-XANTHONE-2-CARBOXYLIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

6-ISOPROPOXY-9-XANTHONE-2-CARBOXYLIC ACID Suppliers

Global( 86)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 32112 58
InvivoChem
+1-708-310-1919 +1-13798911105 sales@invivochem.cn United States 6391 58
TargetMol Chemicals Inc.
support@targetmol.com United States 38596 58
Aladdin Scientific
+1-+1(833)-552-7181 sales@aladdinsci.com United States 57505 58
Amadis Chemical Company Limited
571-89925085 sales@amadischem.com China 131957 58
3B Pharmachem (Wuhan) International Co.,Ltd. 821-50328103-801 18930552037 3bsc@sina.com China 15839 69
Guangzhou Isun Pharmaceutical Co., Ltd 020-39119399 18927568969 isunpharm@qq.com China 4428 55
Shanghai Lollane Biological Technology Co.,Ltd. 021-52996696,15000506266 15000506266 China 4512 55
SPIRO PHARMA eric_feng1954@126.com China 9248 55
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9806 58

View Lastest Price from 6-ISOPROPOXY-9-XANTHONE-2-CARBOXYLIC ACID manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
AH 6809 pictures 2024-11-19 AH 6809
33458-93-4
US $38.00-88.00 / mg 97.59% 10g TargetMol Chemicals Inc.
AH 6809 pictures 2024-11-19 AH 6809
33458-93-4
US $38.00-88.00 / mg 97.59% 10g TargetMol Chemicals Inc.
  • AH 6809 pictures
  • AH 6809
    33458-93-4
  • US $38.00-88.00 / mg
  • 97.59%
  • TargetMol Chemicals Inc.
  • AH 6809 pictures
  • AH 6809
    33458-93-4
  • US $38.00-88.00 / mg
  • 97.59%
  • TargetMol Chemicals Inc.
6-ISOPROPOXY-9-OXOXANTHENE-2-CARBOXYLIC ACID 6-ISOPROPOXY-9-XANTHONE-2-CARBOXYLIC ACID AH 6809 6-(1-Methylethoxy)-9-oxo-9H-xanthene-2-carboxylic acid 6-Isopropoxy-9-oxo-9H-xanthene-2-carboxylic acid AH6809;AH-6809 9H-Xanthene-2-carboxylic acid, 6-(1-methylethoxy)-9-oxo- Prostaglandin Receptor,AH-6809,inhibit,Inhibitor,AH6809,AH 6809 9-oxo-6-(propan-2-yloxy)-9H-xanthene-2-carboxylic acid 33458-93-4