ChemicalBook >> CAS DataBase List >>Palonosetron
Palonosetron
- CAS No.
- 149653-99-6
- Chemical Name:
- Palonosetron
- Synonyms
- CID 148211;Palonosetron USP/EP/BP;(R)-2-((R)-quinuclidin-3-yl)-2,3,3a,4,5,6-hexahydro-1H-benzo[de] isoquinolin-1-one;[r-(r*,r*)]-2-(1-azabicyclo[2.2.2]oct-3-yl)-2,3,3a,4,5,6-hexahydro-1h-benz[de]isoquinolin-1-one;1H-Benz[de]isoquinolin-1-one, 2-(3R)-1-azabicyclo[2.2.2]oct-3-yl-2,3,3a,4,5,6-hexahydro-, (3aR)-
- CBNumber:
- CB62131052
- Molecular Formula:
- C19H24N2O
- Molecular Weight:
- 296.41
- MDL Number:
- MOL File:
- 149653-99-6.mol
- MSDS File:
- SDS
Last updated:2023-03-13 11:54:02
Boiling point | 470.4±45.0 °C(Predicted) |
---|---|
Density | 1.24 |
pka | 9.77±0.33(Predicted) |
FDA UNII | 5D06587D6R |
Palonosetron Chemical Properties,Uses,Production
Indications
Palonosetron is approved by the US FDA for acute and delayed CINV and PONV.
Biological Activity
Palonosetron is a highly selective, high-affinity 5-HT3 receptor antagonist. Due to its structural difference from the first-generation 5-HT3 receptor antagonists, palonosetron has an affinity for the 5-HT3 receptor at least 30 times that of other similar drugs.
in vitro
Palonosetron is neither an inhibitor of CYP1A2, CYP2A6, CYP2B6, CYP2C9, CYP2D6, CYP2E1 and CYP3A4/5 (CYP2C19 not studied) nor does it induce the activity of CYP1A2, CYP2D6 or CYP3A4/5.
Palonosetron Preparation Products And Raw materials
Raw materials
Preparation Products
Palonosetron Suppliers
Global( 37)Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49392 | 58 |
career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29825 | 58 |
Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1026@dideu.com | China | 24295 | 58 |
Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471 | sales@sarms4muscle.com | China | 10522 | 58 |
CD Chemical Group Limited | +8615986615575 | info@codchem.com | China | 20356 | 58 |
Hangzhou MolCore BioPharmatech Co.,Ltd. | +86-057181025280; +8617767106207 | sales@molcore.com | China | 49739 | 58 |
Henan Allgreen Chemical Co.,LTD | +86-37155567971 +86-13633837469 | info@allgreenchem.com | China | 5986 | 58 |
Shanghai Acmec Biochemical Technology Co., Ltd. | +undefined18621343501 | product@acmec-e.com | China | 33350 | 58 |
Aladdin Scientific | +1-+1(833)-552-7181 | sales@aladdinsci.com | United States | 52927 | 58 |
Chembest Research Laboratories Limited | +86-21-20908456 | sales@BioChemBest.com | China | 6008 | 61 |
View Lastest Price from Palonosetron manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2021-07-10 | Palonosetron USP/EP/BP
149653-99-6
|
US $1.10 / g | 1g | 99.9% | 100 Tons Min | Dideu Industries Group Limited |
- Palonosetron USP/EP/BP
149653-99-6
- US $1.10 / g
- 99.9%
- Dideu Industries Group Limited
[r-(r*,r*)]-2-(1-azabicyclo[2.2.2]oct-3-yl)-2,3,3a,4,5,6-hexahydro-1h-benz[de]isoquinolin-1-one
CID 148211
1H-Benz[de]isoquinolin-1-one, 2-(3R)-1-azabicyclo[2.2.2]oct-3-yl-2,3,3a,4,5,6-hexahydro-, (3aR)-
Palonosetron USP/EP/BP
(R)-2-((R)-quinuclidin-3-yl)-2,3,3a,4,5,6-hexahydro-1H-benzo[de] isoquinolin-1-one
149653-99-6