ANTI-SYNUCLEIN, ALPHA
- CAS No.
- Chemical Name:
- ANTI-SYNUCLEIN, ALPHA
- Synonyms
- ANTI-NACP;Anti-SNCA;Anti-PARK1;Anti-PARK4;Anti-MGC110988;ANTI-A-SYNUCLEIN;ANTI-ALPHA-SYNUCLEIN;ANTI-SYNUCLEIN, ALPHA;ALPHA-SYNUCLEIN (AB-1);ANTI-ALPHA-SYNUCLEIN(N-19)
- CBNumber:
- CB6215336
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MFCD02095740
- MOL File:
- Mol file
ANTI-SYNUCLEIN, ALPHA price More Price(15)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | SAB4300529 | Anti-Snca (Ab-136) antibody produced in rabbit affinity isolated antibody | 100μG | $441 | 2024-03-01 | Buy | |
Sigma-Aldrich | SAB4300445 | Anti-SNCA (Ab-129) antibody produced in rabbit affinity isolated antibody | 100μg | $441 | 2024-03-01 | Buy | |
Sigma-Aldrich | SAB4300227 | Anti-phospho-SNCA (pTyr136) antibody produced in rabbit affinity isolated antibody | 100μg | $511 | 2024-03-01 | Buy | |
Sigma-Aldrich | SAB4300226 | Anti-phospho-SNCA (pTyr133) antibody produced in rabbit affinity isolated antibody | 100μg | $511 | 2024-03-01 | Buy | |
Sigma-Aldrich | SAB4300204 | Anti-phospho-SNCA (pTyr125) antibody produced in rabbit affinity isolated antibody | 100μg | $511 | 2024-03-01 | Buy |
ANTI-SYNUCLEIN, ALPHA Chemical Properties,Uses,Production
Uses
Rabbit polyclonal anti-α-Synuclein antibody is used to tag α-Synuclein for detection and quantitation by immunocytochemical and immunohistochemical (IHC) techniques, such as immunoblotting. It is also used as a probe to determine the presence and roles of α-Synuclein in plaques of Alzheimer′s disease (AD) brains.
General Description
The synucleins are a family of soluble presynaptic proteins that are abundant in neurons and include α-synuclein, β-synuclein, and γ-synuclein. Human α-synuclein (also known as the non-amyloid component of plaques precursor protein or NACP) is a 140-amino acid polypeptide that is encoded by a gene on chromosome 4. It was originally isolated from plaques of Alzheimer′s disease (AD) brains as a 19 kDa protein precursor of the highly hydrophobic 35-amino acid peptide, nonamyloid component (NAC) of plaques. The NAC can self-aggregate into fibrils and induce aggregation of the β-amyloid peptide. α-Synuclein is highly abundant in presynaptic terminals, and is a major component of Lewy bodies (LBs). Pathogenic point mutations in the α-synuclein gene are linked to familial Parkinson′s disease (PD) in rare kindreds. However, most neurodegenerative disorders with LBs are associated with abnormal accumulation of wild-type, α-synuclein. α-Synuclein is expressed primarily in brain, but is also expressed in low levels in all tissues examined except liver.
ANTI-SYNUCLEIN, ALPHA Preparation Products And Raw materials
Raw materials
Preparation Products
ANTI-SYNUCLEIN, ALPHA Suppliers
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