ANTI-SYNUCLEIN, ALPHA
|
|
ANTI-SYNUCLEIN, ALPHA 속성
- 저장 조건
- −20°C
- 물리적 상태
- 완충 수용액
안전
위험품 표기 | Xn | ||
---|---|---|---|
위험 카페고리 넘버 | 21/22 | ||
안전지침서 | 36/37 | ||
WGK 독일 | 2 |
ANTI-SYNUCLEIN, ALPHA C화학적 특성, 용도, 생산
용도
Rabbit polyclonal anti-α-Synuclein antibody is used to tag α-Synuclein for detection and quantitation by immunocytochemical and immunohistochemical (IHC) techniques, such as immunoblotting. It is also used as a probe to determine the presence and roles of α-Synuclein in plaques of Alzheimer′s disease (AD) brains.일반 설명
The synucleins are a family of soluble presynaptic proteins that are abundant in neurons and include α-synuclein, β-synuclein, and γ-synuclein. Human α-synuclein (also known as the non-amyloid component of plaques precursor protein or NACP) is a 140-amino acid polypeptide that is encoded by a gene on chromosome 4. It was originally isolated from plaques of Alzheimer′s disease (AD) brains as a 19 kDa protein precursor of the highly hydrophobic 35-amino acid peptide, nonamyloid component (NAC) of plaques. The NAC can self-aggregate into fibrils and induce aggregation of the β-amyloid peptide. α-Synuclein is highly abundant in presynaptic terminals, and is a major component of Lewy bodies (LBs). Pathogenic point mutations in the α-synuclein gene are linked to familial Parkinson′s disease (PD) in rare kindreds. However, most neurodegenerative disorders with LBs are associated with abnormal accumulation of wild-type, α-synuclein. α-Synuclein is expressed primarily in brain, but is also expressed in low levels in all tissues examined except liver.ANTI-SYNUCLEIN, ALPHA 준비 용품 및 원자재
원자재
준비 용품
ANTI-SYNUCLEIN, ALPHA 공급 업체
글로벌( 25)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
---|---|---|---|---|---|
Sigma-Aldrich Chemicals Private Limited | -- |
customerserviceindia@merckgroup.com | India | 6820 | 58 |
Beijing Bolide Biotechnology Co., Ltd. | -- |
1985563437@qq.com | CHINA | 6172 | 58 |
Annuol (Beijing) Biotechnology Co., Ltd. | -- |
inquiry@annoron.com | CHINA | 6434 | 58 |
Beijing Fubo Biotechnology Co., Ltd. | -- |
info@f-biology.com | CHINA | 6039 | 58 |
Suzhou Ruinuode Biotechnology Co., Ltd. | -- |
2090855807@qq.com | CHINA | 6063 | 58 |
Shanghai Beinuo Biotechnology Co., Ltd. | -- |
beinuobio@163.com | CHINA | 6580 | 58 |
Beijing Luyuan Bird Biotechnology Co., Ltd. | -- |
15810802415@139.com | CHINA | 6757 | 58 |
Shanghai Hao Biological Technology Co., Ltd. | -- |
shxiyuanbio@163.com | CHINA | 6921 | 58 |
Beijing Dongge Boye Biotechnology Co., Ltd. | -- |
1861586486@qq.com | CHINA | 6652 | 58 |
Nanjing Sai Ruirui Biotechnology Co., Ltd. | -- |
sales@shrbio.com | CHINA | 6873 | 58 |