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2'-Hydroxy-5'-methoxyacetophenone

CAS No.
705-15-7
Chemical Name:
2'-Hydroxy-5'-methoxyacetophenone
Synonyms
1-(2-HYDROXY-5-METHOXYPHENYL)ETHAN-1-ONE;1-(2-HYDROXY-5-METHOXYPHENYL)ETHANONE;2-HYDROXY-5-METHOXYACETOPHENONE;Ethanone, 1-(2-hydroxy-5-methoxyphenyl)-;2'-Hydro;NSC 338218;ASISCHEM D38760;sulfosulfamic acid;2'-Hydroxy-5'-methoxyacetophene;5-Methoxy-2-hydroxyacetophenone
CBNumber:
CB6234562
Molecular Formula:
C9H10O3
Molecular Weight:
166.17
MDL Number:
MFCD00008731
MOL File:
705-15-7.mol
MSDS File:
SDS
Last updated:2024-04-23 09:40:05

2'-Hydroxy-5'-methoxyacetophenone Properties

Melting point 52 °C(lit.)
Boiling point 254.38°C (rough estimate)
Density 1.1708 (rough estimate)
refractive index 1.5500 (estimate)
Flash point >230 °F
storage temp. Inert atmosphere,Room Temperature
solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
pka 10.65±0.18(Predicted)
form Crystalline Powder
color Yellow
Odor Aromatic, somewhat medicinal, warm, woody -the herbaceous odour of good tenacity.
BRN 1239364
InChIKey MLIBGOFSXXWRIY-UHFFFAOYSA-N
CAS DataBase Reference 705-15-7(CAS DataBase Reference)
NIST Chemistry Reference Ethanone, 1-(2-hydroxy-5-methoxyphenyl)-(705-15-7)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictograms
GHS05,GHS07
Signal word  Danger
Hazard statements  H315-H318-H335
Precautionary statements  P261-P280-P305+P351+P338
Hazard Codes  Xi
Risk Statements  37/38-41-36/37/38
Safety Statements  26-37/39-36/37/39-22
WGK Germany  3
Hazard Note  Irritant
HS Code  29145090
NFPA 704
1
2 0

2'-Hydroxy-5'-methoxyacetophenone price More Price(28)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 114995 2′-Hydroxy-5′-methoxyacetophenone 99% 705-15-7 5g $65.2 2024-03-01 Buy
Sigma-Aldrich 114995 2′-Hydroxy-5′-methoxyacetophenone 99% 705-15-7 25g $94.2 2024-03-01 Buy
TCI Chemical H0868 2'-Hydroxy-5'-methoxyacetophenone >98.0%(GC) 705-15-7 5g $29 2024-03-01 Buy
TCI Chemical H0868 2'-Hydroxy-5'-methoxyacetophenone >98.0%(GC) 705-15-7 25g $130 2024-03-01 Buy
Alfa Aesar A19216 2'-Hydroxy-5'-methoxyacetophenone, 99% 705-15-7 5g $47.65 2024-03-01 Buy
Product number Packaging Price Buy
114995 5g $65.2 Buy
114995 25g $94.2 Buy
H0868 5g $29 Buy
H0868 25g $130 Buy
A19216 5g $47.65 Buy

2'-Hydroxy-5'-methoxyacetophenone Chemical Properties,Uses,Production

Chemical Properties

yellow crystalline powder

Uses

2′-Hydroxy-5′-methoxyacetophenone is observed as a side reaction product of elbs persulphate oxidation of phenols. 2-Hydroxy-5-methoxyacetophenone is also used to prepare substituted chromanone and chromone derivatives as sirtuin 2-selective inhibitors.

Preparation

reparation by reaction of dimethyl sulfate on 2,5-dihydroxyacetophenone, ? with potassium carbonate in acetone at r.t. (74%) ; ? with aqueous sodium hydroxide solution at reflux (35%).

Application

2'-Hydroxy-5'-methoxyacetophenone could find some use in perfume compositions, e. g., in artificial Oakmoss, in New Mown Hay fragrances, and in certain heavy florals. It blends well with Labdanum and with Lavender type oils, and it lends a certain amount of power and undertones to the fragrance.

Synthesis Reference(s)

Synthesis, p. 901, 1985 DOI: 10.1055/s-1985-31380

General Description

2′-Hydroxy-5′-methoxyacetophenone is observed as a side reaction product of elbs persulphate oxidation of phenols.

2'-Hydroxy-5'-methoxyacetophenone Preparation Products And Raw materials

Global( 278)Suppliers
Supplier Tel Email Country ProdList Advantage
Capot Chemical Co.,Ltd.
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Alchem Pharmtech,Inc.
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CONIER CHEM AND PHARMA LIMITED
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Suzhou Ryan Pharmachem Technology Co.,Ltd.
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View Lastest Price from 2'-Hydroxy-5'-methoxyacetophenone manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2'-Hydroxy-5'-methoxyacetophenone pictures 2024-04-23 2'-Hydroxy-5'-methoxyacetophenone
705-15-7
US $950.00 / Kg 1Kg 98 500 Kg R&D Scientific Inc.
2'-Hydroxy-5'-methoxyacetophenone pictures 2019-07-06 2'-Hydroxy-5'-methoxyacetophenone
705-15-7
US $1.00 / KG 1KG 99% Customized Career Henan Chemical Co
5-Methoxy-2-hydroxyacetophenone Acetophenone, 2'-hydroxy-5'-methoxy- 2'-HYDROXY-5'-METHOXYACETOPHENONE 2-HYDROXY-5'-METHOXYACETOPHENONE 2'-HYDROXY-5'-METHOXYACETYLPHENONE ASISCHEM D38760 2'-Hydroxy-5'-methoxyacetophenone 99% NSC 338218 2'-HYDROXY-5'-METHOXYACETOPHENONE,99% 2'-Hydro 2'-Hydroxy-5'-methoxyacetophene JR-6832, 1-(2-Hydroxy-5-methoxyphenyl)ethanone, 97% sulfosulfamic acid 2'-Hydroxy-5'-methoxyacetophenone> Ethanone, 1-(2-hydroxy-5-methoxyphenyl)- 2-HYDROXY-5-METHOXYACETOPHENONE 1-(2-HYDROXY-5-METHOXYPHENYL)ETHANONE 1-(2-HYDROXY-5-METHOXYPHENYL)ETHAN-1-ONE 2'-Hydroxy-5'-methoxyacetophenone 705-15-7 Building Blocks Carbonyl Compounds C9 Ketones Organic Building Blocks ketone| alcohol Aromatic Acetophenones & Derivatives (substituted) C9 Carbonyl Compounds Ketones