CANGRELOR
- CAS No.
- 163706-06-7
- Chemical Name:
- CANGRELOR
- Synonyms
- Kengreal;CANGRELOR;Cangrelor 13CD3;Cangrelor 13CD7;Cangrelor sodium;Cangrelor free acid;Cangrelor (AR-C69931);AR-C69931 (Cangrelor);163706-06-7 CANGRELOR;CANGRELOR;ARC69931;ARC 69931
- CBNumber:
- CB62451277
- Molecular Formula:
- C17H25Cl2F3N5O12P3S2
- Molecular Weight:
- 776.36
- MDL Number:
- MFCD09837758
- MOL File:
- 163706-06-7.mol
| Boiling point | 979.0±75.0 °C(Predicted) |
|---|---|
| Density | 2.08 |
| pka | 0.82±0.50(Predicted) |
| FDA UNII | 6AQ1Y404U7 |
| ATC code | B01AC25 |
SAFETY
Risk and Safety Statements
| Hazardous Substances Data | 163706-06-7(Hazardous Substances Data) |
|---|
CANGRELOR price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | C175230 | Cangrelor | 163706-06-7 | 10mg | $4620 | 2021-12-16 | Buy |
| Crysdot | CD70001961 | Cangrelor 95+% | 163706-06-7 | 5mg | $450 | 2021-12-16 | Buy |
| Crysdot | CD70001961 | Cangrelor 95+% | 163706-06-7 | 10mg | $750 | 2021-12-16 | Buy |
| DC Chemicals | DC7005 | Cangrelorfreeacid >98% | 163706-06-7 | 250mg | $1300 | 2021-12-16 | Buy |
CANGRELOR Chemical Properties,Uses,Production
Uses
Cangrelor is a P2Y12 inhibitor used as an antiplatelet drug for intravenous application.
Uses
Anti-platelet agent.
Definition
ChEBI: A nucleoside triphosphate analogue that is 5'-O-[({[dichloro(phosphono)methyl](hydroxy)phosphoryl}oxy)(hydroxy)phosphoryl]adenosine carrying additional 2-(methylsulfanyl)ethyl and (3,3,3-trifluoropropyl)sulfanyl substituents at positions N6 and C2 respectively. Used (in the form of its tetrasodium salt) as an intravenous antiplatelet drug that prevents formation of harmful blood clots in the coronary arteries.
Clinical Use
Direct P2Y12 platelet receptor antagonist:
Antiplatelet for patients undergoing a PCI
in vivo
Cangrelor tetrasodium (10 mg/kg) not only significantly decreases BLM-induced release of inflammatory cytokines (PF4, CD40 L and MPO), but also decreases the increment of platelets, neutrophils and platelet-neutrophil aggregates in the fibrotic lung and in the peripheral blood of BLM-treated mice[2].
IC 50
P2Y12 Receptor
Metabolism
Cangrelor is deactivated rapidly in the plasma by dephosphorylation to form its main metabolite, a nucleoside. Following a 2 micrograms/kg/min infusion of [3 H] cangrelor, 58% was found in urine and the remaining 35% was found in faeces, presumably following biliary excretion.
CANGRELOR Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| BEIJING SJAR TECHNOLOGY DEVELOPMENT CO., LTD. | +86-18600796368 +86-18600796368 | sales@sjar-tech.com | China | 485 | 58 |
| Shanghai Yingrui Biopharma Co., Ltd. | +86-21-33585366 - 03@ | sales03@shyrchem.com | CHINA | 738 | 60 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29858 | 58 |
| Nanjing Dolon Biotechnology Co.,Ltd. | 18905173768 | sales@dolonchem.com | CHINA | 2972 | 58 |
| Jinan Shengqi pharmaceutical Co,Ltd | 86+18663751872 | christine@shengqipharm.com | CHINA | 491 | 58 |
| Shochem(Shanghai) Co.,Ltd | 86-21-50800795 | info@shochem.com | CHINA | 288 | 58 |
| Shanghai Yingrui Biopharma Co.,Ltd | 21-33585366 | export01@shyrchem.com | CHINA | 1319 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49732 | 58 |
| Qiuxian Baitai New Material Co., LTD | +8618330912755 | sale2@hbyalin.com | China | 1658 | 58 |
| AFINE CHEMICALS LIMITED | +86-0571-85134551 | sales@afinechem.com | China | 15395 | 58 |
View Lastest Price from CANGRELOR manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-04-25 | Cangrelor
163706-06-7
|
US $0.00 / KG | 10g | 99%min | 10kg | WUHAN FORTUNA CHEMICAL CO., LTD | |
 |
2025-01-13 | Cangrelor
163706-06-7
|
US $0.00 / g | 1g | More Than 99% | 100kg/Month | BEIJING SJAR TECHNOLOGY DEVELOPMENT CO., LTD. | |
 |
2021-11-23 | CANGRELOR
163706-06-7
|
US $20.00 / g | 10g | 99.99% | 5ton/Month | Qiuxian Baitai New Material Co., LTD |