ChemicalBook >> CAS DataBase List >>2'-O-MOE-5MeU-3'-phosphoramidite
2'-O-MOE-5MeU-3'-phosphoramidite
- CAS No.
- 163878-63-5
- Chemical Name:
- 2'-O-MOE-5MeU-3'-phosphoramidite
- Synonyms
- 5-Me-DMT-2'-O-Me-Ur;5'-O-DMT-2'-O-MOE-T-CE;5-Me-DMT-2'-O-MOE-U-CE;2'-MOE Thymidine Amidite;2’-MOE-T Phosphoramidite;2'-MOE-U CE Phosphoramidite;5-Methyl-2 '- Methoxyuridine;2'-O-MOE-T-CE Phosphoramidite;5-Methyl-DMT-2'-methoxyuridine;2'-O-MOE-5-Me-U Phosphoramidite
- CBNumber:
- CB62459682
- Molecular Formula:
- C43H55N4O10P
- Molecular Weight:
- 818.89
- MDL Number:
- MFCD11505865
- MOL File:
- 163878-63-5.mol
- MSDS File:
- SDS
Last updated:2025-01-27 09:38:02
| storage temp. | -20°C |
|---|---|
| form | Solid |
| pka | 9.55±0.10(Predicted) |
| color | White to off-white |
| InChIKey | YFRRKZDUDXHJNC-UHDLEJOUNA-N |
| SMILES | O(C(C1=CC=C(OC)C=C1)(C1=CC=C(OC)C=C1)C1=CC=CC=C1)C[C@H]1O[C@@H](N2C=C(C)C(=O)NC2=O)[C@H](OCCOC)[C@@H]1OP(N(C(C)C)C(C)C)OCCC#N |&1:25,27,37,43,r| |
| UNSPSC Code | 41116105 |
| NACRES | NA.51 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302 |
| Precautionary statements | P264-P270-P301+P312-P330-P501 |
2'-O-MOE-5MeU-3'-phosphoramidite Chemical Properties,Uses,Production
Chemical Properties
white to off-white powder
Uses
5''-O-DMT-2''-O-methyl-5-methyluridine is a uridine-derived oligonucleoside (U829910) used in the synthetic preparation of nucleic acids.
General Description
2'-O-MOE-5MeU-3'-phosphoramidite is a phosphorite monomer that can be used in the synthesis of oligonucleotides.
General Description
Like the very similar 2’-OMe backbone, the 2’-O-methoxyethyl-RNA (2’-MOE) backbone provides enhanced duplex stability, significant nuclease resistance and relatively low toxicity. As a result, 2’-MOE has been an attractive backbone for many therapeutic candidates, several of which have been approved by the FDA. These drugs have included 1) 2’-MOE/DNA chimeras to facilitate RNase H cleavage of target RNA sequences as well as 2) steric blocking oligonucleotides to alter the splicing of mRNA. The standard 2’-MOE nucleotides are A, 5-Me-C, G and 5-Me-U.
2'-O-MOE-5MeU-3'-phosphoramidite Preparation Products And Raw materials
Raw materials
Preparation Products
2'-O-MOE-5MeU-3'-phosphoramidite Suppliers
Global( 104)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Daken Advanced Materials Co.,Ltd | +86-371-+86-371-66670886 | info@dakenam.com | China | 19809 | 58 |
| Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 | admin@nexconn.com | China | 10406 | 58 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19552 | 58 |
| NewCan Biotech Limited | +86-0571-86912261 +8613735419629 | sales@newcanbio.com | China | 9985 | 58 |
| Zhejiang Hengkang Pharmaceutical Co., Ltd. | +86-576-83372028 +86-18868723926 | bd1@hengkangpharm.cn | China | 119 | 58 |
| Wuhu Nuowei chemistry Co., Ltd. | +86-0553-2911116-802 +86-18055311600 | sales1@nuowei-chem.com | China | 1638 | 58 |
| Henan Aochuang Chemical Co.,Ltd. | +86-0371-63689365 +8618638391208 | sales@aochuangchem.com | China | 9297 | 58 |
| TargetMol Chemicals Inc. | support@targetmol.com | United States | 38630 | 58 | |
| Chemtour Biotech Co., Ltd | +8617327281506 | market@chemtour.com | China | 1521 | 58 |
| SUZHOU SENFEIDA CHEMICAL CO.,LTD | +86-0512-83500002 +8615195660023 | sales@senfeida.com | China | 26362 | 58 |
View Lastest Price from 2'-O-MOE-5MeU-3'-phosphoramidite manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-04-04 | 5'-O-DMT-2'-O-(2-methoxyethyl)-5-methyluridine 3'-CE phosphoramidite
163878-63-5
|
US $0.00-0.00 / kg | 1kg | 98% | 1Ton | Henan Aochuang Chemical Co.,Ltd. | |
 |
2024-10-24 | 2'-O-MOE-5MeU-3'-phosphoramidite
163878-63-5
|
US $30.00 / mg | 10g | TargetMol Chemicals Inc. | |||
 |
2024-08-08 | 5'-O-DMT-2'-O-MOE-T-CE
163878-63-5
|
US $0.00 / mg | 100mg | ≥98% | 20tons | Hefei Huana Biomedical Technology Co.,Ltd. |
-
- 5'-O-DMT-2'-O-(2-methoxyethyl)-5-methyluridine 3'-CE phosphoramidite
163878-63-5
- US $0.00-0.00 / kg
- 98%
- Henan Aochuang Chemical Co.,Ltd.
-
- 2'-O-MOE-5MeU-3'-phosphoramidite
163878-63-5
- US $30.00 / mg
- TargetMol Chemicals Inc.
-
- 5'-O-DMT-2'-O-MOE-T-CE
163878-63-5
- US $0.00 / mg
- ≥98%
- Hefei Huana Biomedical Technology Co.,Ltd.
163878-63-5(2'-O-MOE-5MeU-3'-phosphoramidite)Related Search:
5'-O-DMT-2'-O-methyl-5-methyluridine
5-Me-DMT-2'-O-Me-Ur
5-Methyl-5'-O-(4,4'-Dimethoxytrityl)-2'-O-methyl-uridine
2'-O-MOE-5MeU-3'-phosphoramidite
5'-O-DMTR-2'-O-(2-METHOXYETHYL)-5-METHYLURIDINE-3'-CED-PHOSPHORAMIDITE
5'-O-[Bis(4-methoxyphenyl)phenylmethyl]-2'-O-(2-methoxyethyl)-5-methyluridine 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]
(2R,3R,4R,5R)-2-((BIS(4-METHOXYPHENYL)(PHENYL)METHOXY)METHYL)-4-(2-METHOXYETHOXY)-5-(5-METHYL-2,4-DIOXO-3,4-DIHYDROPYRIMIDIN-1(2H)-YL)TETRAHYDROFURAN-3-YL 2-CYANOETHYL DIISOPROPYLPHOSPHORAMIDITE
2-O-MOE-5-Methyl-Uridine Phosphoramidite
2'-O-MOE-T-CE Phosphoramidite
5-methyl-5'-O-(4, 4'-dimethoxytrityl)-2'-O-methoxyethyl-uridine-3'-cyanoethyl Phosphoramidite
DMT-2'-O-MOE-T-CE-Phosphoramidite
Uridine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-(2-methoxyethyl)-5-methyl-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]
5’-O-DMTr-2’-O-(2-methoxyethyl)-5-methyluridine-3’-CED-phosphoramidite, 2’-O-MOE -5MeU-3’-phosphoramidite
5'-O-DMT-5-Methy-2'-O-(2-methoxyethyl)uridine 3'-CE phosphoramidite
2'-O-MOE-5-Me-U Phosphoramidite
5'-O-(4,4'-Dimethoxytrityl)-2'-O-methoxyethyl-5-methyl-uridine-3'-O-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite
DMT-2′O-MOE-rMeU Phosphoramidite
5'-O-DMT-2’-MOE-5-methyluridine-CE-Phosphoramidite
5-Me-DMT-2'-O-MOE-U-CE-Phosphoramidite
2’-O-MOE-5MeU-3’-phosphoramidite,5’-O-DMTr-2’-O-(2-methoxyethyl)-5-methyl uridine-3’-CED-phosphoramidite MOE-5MeU-PAM
2’-O-MOE-5MeU-3’-phosphoramidit
2'-O-MOE-5-Me-U -CE Phosphoramidite
5'-O-DMT-2'-O-MOE-T-CE
2'-MOE-U CE Phosphoramidite
5'-O-DMT-2'-O-MOE- 5-Me-Uridine -3’-Cyanoethyl Phosphoramidite
2'-MOE Thymidine Amidite
5-Me-DMT-2'-O-MOE-U-CE
DMT-2''O-MOE-rMeU Amidite，septum
5-Methyl-2 '- Methoxyuridine
DMTr-2'-O-MOE-rT-3'-CE-Phosphoramidite
2,4-DIOXO-3,4-DIHYDROPYRIMIDIN-1(2H)-YL)TETRAHYDROFURAN-3-YL 2-CYANOETHYL DIISOPROPYLPHOSPHORAMIDITE
5’-O-(4, 4’-Dimethoxytrityl)-5-methyl-2’-O-(2-methoxyethyl)uridine-3’-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite
5'-ODMT-2'-OMOE-5-methyluridine-3'-OCEPA
2’-O-MOE-5MeU-3’-phospho ramidite
2'-O-MOE-5-Me-U-CE-Phosphoramidite
5-Me-2'-O-MOE-5'-O-DMT-Me-U-CE-Phosphoramidite
2'-O-MOE-5-Me-rU Phosphoramidite
[5'-O-(4,4'-dimethoxytriphenylmethyl)-2'-O-(2-methoxyethyl)-5-methyluridin-3'-O-yl]-2-cyanoethyl-N,N'-diisopropylphosphoramidite
2’-MOE-T Phosphoramidite
5-Methyl-DMT-2'-methoxyuridine
(2’-MOE-T) 5-methyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-methoxyethyl-uridine-3'-cyanoethyl
Phosphoramidite
163878-63-5
C43H55N4O10P
Amidite