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ChemicalBook >> CAS DataBase List >>4-Methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]benzoic acid methyl ester

4-Methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]benzoic acid methyl ester

4-Methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]benzoic acid methyl ester Structure
4-Methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]benzoic acid methyl ester structure
CAS No.
917392-54-2
Chemical Name:
4-Methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]benzoic acid methyl ester
Synonyms
Nilotinib Impurity 44;NILOTINIB EP IMPURITY G;917392-54-2;Nilotinib Impurity 12 (Nilotinib EP Impurity G);Nilotinib Hydrochloride Monohydrate EP Impurity G; 4-Methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino;methyl 4-methyl-3-[[4-(3-pyridyl)pyrimidin-2-yl]amino]benzoate;methyl 4-methyl-3-[[4-(3-pyridyl)pyrimidin-2-yl]amino]benzoa...;Methyl 4-Methyl-3-((4-(pyridin-3-yl)pyriMidin-2-yl)aMino)benzoate;4-Methyl-3-(4-pyridin-3-yl-pyriMidin-2-ylaMino)-benzoic acid Methyl ester
CBNumber:
CB62490045
Molecular Formula:
C18H16N4O2
Molecular Weight:
320.35
MDL Number:
MFCD16619370
MOL File:
917392-54-2.mol
Last updated:2024-04-25 13:42:50
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4-Methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]benzoic acid methyl ester Properties

Melting point 148 - 150°C
Boiling point 538.6±60.0 °C(Predicted)
Density 1.258
storage temp. 2-8°C
solubility Chloroform (Slightly), DMSO (Slightly)
form Solid
pka 2.70±0.12(Predicted)
color Pale Yellow to Light Beige
FDA UNII HKX2YWY42Y

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P280-P301+P312-P304+P340
HS Code  2916399090

4-Methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]benzoic acid methyl ester price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC M325060 Methyl4-Methyl-3-[[4-(pyridin-3-yl)pyrimidin-2-yl]amino]benzoate 917392-54-2 500mg $530 2021-12-16 Buy
Apolloscientific OR350263 Methyl4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)benzoate 917392-54-2 1g $464 2021-12-16 Buy
American Custom Chemicals Corporation CHM0393212 METHYL-4-METHYL-3-((4-(PYRIDIN-3-YL)PYRIMIDIN-2-YL)AMINO)BENZOATE 95.00% 917392-54-2 5MG $498.84 2021-12-16 Buy
SynQuest Laboratories 4H58-1-ZQ Methyl 4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)benzoate 917392-54-2 1g $512 2021-12-16 Buy
Apolloscientific OR350263 Methyl4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)benzoate 917392-54-2 250mg $143 2021-12-16 Buy
Product number Packaging Price Buy
M325060 500mg $530 Buy
OR350263 1g $464 Buy
CHM0393212 5MG $498.84 Buy
4H58-1-ZQ 1g $512 Buy
OR350263 250mg $143 Buy

4-Methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]benzoic acid methyl ester Chemical Properties,Uses,Production

Uses

Methyl 4-methyl-3-[[4-(pyridin-3-yl)pyrimidin-2-yl]amino]benzoate is an intermediate used in the synthesis of 4-Methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]benzamide (M326838), which is an impurity of Nilotinib (N465300), a possible agent in the treatment of chronic myelogenous leukemia.

4-Methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]benzoic acid methyl ester synthesis

104901-43-1
66521-66-2
917392-54-2
Synthesis of 4-Methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]benzoic acid methyl ester from Methyl 3-bromo-4-methylbenzoate and 4-(Pyridin-3-yl)pyrimidin-2-amine

4-Methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]benzoic acid methyl ester Preparation Products And Raw materials

Raw materials

Methyl 3-amino-4-methylbenzoate 3-[(aMinoiMinoMethyl)aMino]-4-Methylbenzoic acid Methyl ester Mononitrate 4-(3-Pyridyl)-2-chloropyrimidine Methyl 3-bromo-4-methylbenzoate METHYL 3-IODO-4-METHYLBENZOATE
3-Pyridylboronic acid 4-(Pyridin-3-yl)pyrimidin-2-amine 3-Acetylpyridine Methanol

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Preparation Products

4-Methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]benzoic acid Nilotinib

4-Methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]benzoic acid methyl ester Suppliers

Global( 113)Suppliers
Supplier Tel Email Country ProdList Advantage
Henan Fengda Chemical Co., Ltd 		+86-371-86557731 +86-13613820652 info@fdachem.com China 20287 58
Beijing Cooperate Pharmaceutical Co.,Ltd 		010-60279497 sales01@cooperate-pharm.com CHINA 1803 55
career henan chemical co 		+86-0371-86658258 +8613203830695 sales@coreychem.com China 29881 58
Chongqing Chemdad Co., Ltd 		+86-023-6139-8061 +86-86-13650506873 sales@chemdad.com China 39894 58
Alchem Pharmtech,Inc. 		8485655694 sales@alchempharmtech.com United States 63687 58
Shanghai Yingrui Biopharma Co.,Ltd 		21-33585366 export01@shyrchem.com CHINA 1319 58
CONIER CHEM AND PHARMA LIMITED 		+8618523575427 sales@conier.com China 49374 58
SHANGHAI T&W PHARMACEUTICAL CO., LTD. 		+86-021-61551413 +8618813727289 contact@trustwe.com China 5738 58
Dayang Chem (Hangzhou) Co.,Ltd. 		571-88938639 +8617705817739 info@dycnchem.com China 52849 58
CD Chemical Group Limited 		+8615986615575 info@codchem.com China 20342 58
Supplier Advantage
Henan Fengda Chemical Co., Ltd 		58
Beijing Cooperate Pharmaceutical Co.,Ltd 		55
career henan chemical co 		58
Chongqing Chemdad Co., Ltd 		58
Alchem Pharmtech,Inc. 		58
Shanghai Yingrui Biopharma Co.,Ltd 		58
CONIER CHEM AND PHARMA LIMITED 		58
SHANGHAI T&W PHARMACEUTICAL CO., LTD. 		58
Dayang Chem (Hangzhou) Co.,Ltd. 		58
CD Chemical Group Limited 		58

View Lastest Price from 4-Methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]benzoic acid methyl ester manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Nilotinib EP Impurity G pictures 2024-09-20 Nilotinib EP Impurity G
917392-54-2
 US $0.00-0.00 / mg 10mg 0.98 10g ShenZhen H&D Pharmaceutical Technology Co., LTD
4-Methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino pictures 2024-03-29 4-Methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino
917392-54-2
 US $8.00-1.00 / KG 1KG 99% g-kg-tons, free sample is available Henan Fengda Chemical Co., Ltd
4-Methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]benzoic acid methyl ester pictures 2019-07-06 4-Methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]benzoic acid methyl ester
917392-54-2
 US $1.00 / KG 1KG 99% 20kg Career Henan Chemical Co

917392-54-2(4-Methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]benzoic acid methyl ester)Related Search:

NILOTINIB IMPURITY 11 4-Methyl-N-(3-(5-Methyl-1H-iMidazol-1-yl)-5-(trifluoroMethyl)phenyl)-3-((4-(pyridin-3-yl)pyriMidin-2-yl)aMino)benzaMide 3-(5-Methyl-1H-iMidazol-1-yl)-5-(trifluoroMethyl)benzenaMine 3-[(Aminoiminomethyl)amino]-4-methylbenzoic acid ethyl ester mononitrate 1H-IMidazole, 4-Methyl-1-[3-nitro-5-(trifluoroMethyl)phenyl]-
3-(4-Methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)benzonitrile 4-Methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]benzoic acid Benzenamine, 3-(2-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)- Methyl 3-amino-4-methylbenzoate Nilotinib Impurity 10
Nilotinib N-Oxide Nilotinib Impurity 7 Nilotinib genotoxic impurity 3 Nilotinib Impurity 1 Nilotinib Impurity 20
3-Amino-4-methylbenzoic acid Nilotinib Impurity 28 Nilotinib impurity 3

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4-Methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]benzoic acid methyl ester 4-Methyl-3-(4-pyridin-3-yl-pyriMidin-2-ylaMino)-benzoic acid Methyl ester Methyl 4-Methyl-3-((4-(pyridin-3-yl)pyriMidin-2-yl)aMino)benzoate, Methyl 4-Methyl-3-(4-(pyridin-3-yl)pyriMidin-2-ylaMino)benzoate Methyl 4-Methyl-3-((4-(pyridin-3-yl)pyriMidin-2-yl)aMino)benzoate Benzoicacid, 4-Methyl-3-[[4-(3-pyridinyl)-2-pyriMidinyl]aMino]-, Methyl ester methyl 4-methyl-3-[[4-(3-pyridyl)pyrimidin-2-yl]amino]benzoate NILOTINIB EP IMPURITY G methyl 4-methyl-3-[[4-(3-pyridyl)pyrimidin-2-yl]amino]benzoa... Nilotinib Impurity 12 (Nilotinib EP Impurity G) 917392-54-2 Nilotinib Hydrochloride Monohydrate EP Impurity G 4-Methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino Nilotinib Impurity 44 917392-54-2