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ChemicalBook >> CAS DataBase List >>6-Bromo-3-iodoimidazo[1,2-a]pyrazine

6-Bromo-3-iodoimidazo[1,2-a]pyrazine

6-Bromo-3-iodoimidazo[1,2-a]pyrazine Structure
6-Bromo-3-iodoimidazo[1,2-a]pyrazine structure
CAS No.
1245644-42-1
Chemical Name:
6-Bromo-3-iodoimidazo[1,2-a]pyrazine
Synonyms
6-Bromo-3-iodoimidazo[1,2-a]pyrazine;Imidazo[1,2-a]pyrazine, 6-bromo-3-iodo-
CBNumber:
CB62500133
Molecular Formula:
C6H3BrIN3
Molecular Weight:
323.92
MDL Number:
MFCD18072708
MOL File:
1245644-42-1.mol
MSDS File:
SDS
Last updated:2026-11-04 16:59:27
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6-Bromo-3-iodoimidazo[1,2-a]pyrazine Properties

Density 2.64
storage temp. under inert gas (nitrogen or Argon) at 2–8 °C
pka -0.05±0.30(Predicted)
Appearance Light yellow to yellow Solid
Comptox DTXSID DTXSID40718278

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H335-H302-H319-H315
Precautionary statements  P264-P280-P305+P351+P338-P337+P313P-P264-P270-P301+P312-P330-P501-P264-P280-P302+P352-P321-P332+P313-P362

6-Bromo-3-iodoimidazo[1,2-a]pyrazine price More Price(28)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Activate Scientific AS40530 6-Bromo-3-iodoimidazo[1,2-a]pyrazine 95% 1245644-42-1 1g $35 2026-06-04 Buy
Activate Scientific AS40530 6-Bromo-3-iodoimidazo[1,2-a]pyrazine 95% 1245644-42-1 5g $152 2026-06-04 Buy
Activate Scientific AS40530 6-Bromo-3-iodoimidazo[1,2-a]pyrazine 95% 1245644-42-1 25g $620 2026-06-04 Buy
ACHEMBLOCK M15190 6-Bromo-3-iodo-imidazo[1,2-a]pyrazine 97% 1245644-42-1 25G $370 2026-05-27 Buy
ACHEMBLOCK M15190 6-Bromo-3-iodo-imidazo[1,2-a]pyrazine 97% 1245644-42-1 100G $1110 2026-05-27 Buy
Product number Packaging Price Buy
AS40530 1g $35 Buy
AS40530 5g $152 Buy
AS40530 25g $620 Buy
M15190 25G $370 Buy
M15190 100G $1110 Buy

6-Bromo-3-iodoimidazo[1,2-a]pyrazine Chemical Properties, Uses, Production

Synthesis

6-Bromoimidazo[1,2-a]pyrazine

912773-24-1

6-Bromo-3-iodoimidazo[1,2-a]pyrazine

1245644-42-1

General procedure for the synthesis of 6-bromo-3-iodoimidazo[1,2-a]pyrazines from 2-bromoimidazo[1,2-a]pyrazines: 6-bromoimidazo[1,2-a]pyrazines (500 mg, 2.52 mmol) and N-iodosuccinimide (NIS, 852 mg, 3.79 mmol) were dissolved in N,N-dimethylformamide (DMF, 10 mL) in N,N-dimethylformamide (DMF, 10 mL), and after degassing, the reaction mixture was heated to 60 °C and kept for 10 hours. After completion of the reaction, the mixture was cooled to room temperature and extracted with dichloromethane (DCM). The organic phase was washed sequentially with aqueous sodium thiosulfate (Na2S2O3) and saturated saline and dried over anhydrous sodium sulfate (Na2SO4). After concentration, the crude product was purified by column chromatography (petroleum ether: ethyl acetate = 5:1) to afford 6-bromo-3-iodoimidazo[1,2-a]pyrazine (530 mg, 65% yield). The product was confirmed by 1H-NMR (CDCl3, 400 MHz): δ 8.75 (s, 1H), 8.18 (s, 1H), 7.82 (s, 1H). Mass spectrometry (MS) analysis showed (M+H)+: 324/326.

References

[1] Patent: WO2013/34048, 2013, A1. Location in patent: Page/Page column 74; 75
[2] Patent: EP2818471, 2014, A1. Location in patent: Paragraph 0191; 0192

6-Bromo-3-iodoimidazo[1,2-a]pyrazine Preparation Products And Raw materials

Raw materials

6-Bromoimidazo[1,2-a]pyrazine N,N-Dimethylformamide N-Iodosuccinimide

Preparation Products

6-Bromo-3-iodoimidazo[1,2-a]pyrazine Suppliers

Global Suppliers ( 66)
Supplier Tel Email Country ProdList Advantage
Pure Chemistry Scientific Inc. 001-857-928-2050 or 1-888-588-9418 sales@chemreagents.com United States 10174 62
Shanghai Hanhong Scientific Co.,Ltd. 021-54306202 13764082696 info@hanhongsci.com China 42917 64
Shanghai Sunway Pharmaceutical Technology Co., Ltd 13761987713 hxzheng@sunwaypharm.cn China 8663 57
Shanghai Topbiochem Technology Co., Ltd +86-21-60341587 sales@topbiochem.com China 6166 58
SuZhou ShiYa Biopharmaceuticals, Inc. 86(512)5235 8471 17715136450 sales@shiyabiopharm.com China 4167 58
Bide Pharmatech Ltd. 400-164-7117 18317119277 product02@bidepharm.com China 40000 60
Nanjing Fast Bio-Pharmaceutical Co.,Ltd. 025-58390181 58390186 18912901218 sales@fastchem.cn China 162 60
Mashilabs (Shanghai) Co.,Ltd. 19916721580 mafarm@126.com China 4532 58
Shanghai HuanChuan Industry Co.,Ltd. 021-61478794 sales@hcshhai.com China 9781 50
Shanghai Synteam Biochem CO.,ltd +86-021-58380978 13482386415 info@systeambc.com China 897 50
Supplier Advantage
Pure Chemistry Scientific Inc. 62
Shanghai Hanhong Scientific Co.,Ltd. 64
Shanghai Sunway Pharmaceutical Technology Co., Ltd 57
Shanghai Topbiochem Technology Co., Ltd 58
SuZhou ShiYa Biopharmaceuticals, Inc. 58
Bide Pharmatech Ltd. 60
Nanjing Fast Bio-Pharmaceutical Co.,Ltd. 60
Mashilabs (Shanghai) Co.,Ltd. 58
Shanghai HuanChuan Industry Co.,Ltd. 50
Shanghai Synteam Biochem CO.,ltd 50

View Latest Price from 6-Bromo-3-iodoimidazo[1,2-a]pyrazine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
6-Bromo-3-iodoimidazo[1,2-a]pyrazine pictures 2019-07-06 6-Bromo-3-iodoimidazo[1,2-a]pyrazine
1245644-42-1
 $1.00 1KG 99% Career Henan Chemical Co

6-Bromo-3-iodoimidazo[1,2-a]pyrazine Spectrum

6-Bromo-3-iodoimidazo[1,2-a]pyrazine(1245644-42-1)1HNMR

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