Amino-PEG2-acid
- CAS No.
- 791028-27-8
- Chemical Name:
- Amino-PEG2-acid
- Synonyms
- NH2-PEG2-COOH;H2N-PEG2-CH2CH2COOH;Amino-PEG2-C2-acid;Amino-PEG2-acid;Amino-PEG2-COOH;AMINE-PEG2-COOH;H2N-(CH2CH2O)2-CH2CH2COOH;Amino-PEG2-propionic acid;α-amine-ω-propionic acid diethylene glycol;Α-AMINE-Ω-PROPIONIC ACID DIETHYLENE GLYCOL
- CBNumber:
- CB62501433
- Molecular Formula:
- C7H15NO4
- Molecular Weight:
- 177.2
- MDL Number:
- MFCD20926377
- MOL File:
- 791028-27-8.mol
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS07 |
---|---|
Signal word | Warning |
Hazard statements | H302-H315-H319-H335 |
Precautionary statements | P280-P305+P351+P338 |
HS Code | 2918999090 |
Amino-PEG2-acid price More Price(26)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
TRC | A577183 | Amino-PEG2Acid | 791028-27-8 | 10mg | $45 | 2021-12-16 | Buy |
TRC | A577183 | Amino-PEG2Acid | 791028-27-8 | 100mg | $130 | 2021-12-16 | Buy |
Biosynth Carbosynth | FP73006 | 3-(2-(2-Aminoethoxy)ethoxy)-propanoic acid | 791028-27-8 | 250mg | $160 | 2021-12-16 | Buy |
Biosynth Carbosynth | FP73006 | 3-(2-(2-Aminoethoxy)ethoxy)-propanoic acid | 791028-27-8 | 50mg | $50 | 2021-12-16 | Buy |
Biosynth Carbosynth | FP73006 | 3-(2-(2-Aminoethoxy)ethoxy)-propanoic acid | 791028-27-8 | 100mg | $80 | 2021-12-16 | Buy |
Amino-PEG2-acid Chemical Properties,Uses,Production
Description
Amino-PEG2-acid is a PEG reagent containing an amino group with a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.
Biological Activity
Amino-PEG2-C2-acid is a cleavable 3-unit PEG ADClinker for the synthesis of antibody-drug conjugated Ck (ADC). It is also a PEG-based PROTAClinker that can be used for PROTAC synthesis.
in vivo
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
Amino-PEG2-acid Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
airuikechemical co., ltd. | +undefined86-15315557071 | sales02@sdzhonghuimaterial.com | China | 983 | 58 |
9i LLC | +18039569191 | MWan@NiNeiLab.com | United States | 418 | 58 |
Nanjing ChemLin Chemical Industry Co., Ltd. | 025-83697070 | product@chemlin.com.cn | CHINA | 3009 | 60 |
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32957 | 60 |
career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29884 | 58 |
Accela ChemBio Inc. | +1-858-6993322 | info@accelachem.com | United States | 17322 | 58 |
Chengdu Pukang Biotechnology Co., Ltd | 028-82550498 | export@pu-kang.com | CHINA | 210 | 58 |
Shandong chuangyingchemical Co., Ltd. | 18853181302 | sale@chuangyingchem.com | CHINA | 5906 | 58 |
Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | sales@chemdad.com | China | 39894 | 58 |
SHANGHAI T&W PHARMACEUTICAL CO., LTD. | +86-021-61551413 +8618813727289 | contact@trustwe.com | China | 5738 | 58 |
View Lastest Price from Amino-PEG2-acid manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2024-10-24 | Amino-PEG2-C2-acid
791028-27-8
|
US $0.00 / mg | 10g | TargetMol Chemicals Inc. | ||||
2024-10-15 | α-amine-ω-propionic acid diethylene glycol
791028-27-8
|
US $0.00-0.00 / Kg | 1Kg | 99.9% | 200tons | airuikechemical co., ltd. | ||
2024-03-23 | Amino-PEG2-COOH
791028-27-8
|
US $0.00 / mg | 250mg | >98.00% | 250mg | Xian confluore Biological Technology Co., Ltd. |
- Amino-PEG2-C2-acid
791028-27-8
- US $0.00 / mg
- TargetMol Chemicals Inc.
- α-amine-ω-propionic acid diethylene glycol
791028-27-8
- US $0.00-0.00 / Kg
- 99.9%
- airuikechemical co., ltd.
- Amino-PEG2-COOH
791028-27-8
- US $0.00 / mg
- >98.00%
- Xian confluore Biological Technology Co., Ltd.
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