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Amino-PEG2-acid

CAS No.
791028-27-8
Chemical Name:
Amino-PEG2-acid
Synonyms
NH2-PEG2-COOH;H2N-PEG2-CH2CH2COOH;Amino-PEG2-C2-acid;Amino-PEG2-acid;Amino-PEG2-COOH;AMINE-PEG2-COOH;H2N-(CH2CH2O)2-CH2CH2COOH;Amino-PEG2-propionic acid;α-amine-ω-propionic acid diethylene glycol;Α-AMINE-Ω-PROPIONIC ACID DIETHYLENE GLYCOL
CBNumber:
CB62501433
Molecular Formula:
C7H15NO4
Molecular Weight:
177.2
MDL Number:
MFCD20926377
MOL File:
791028-27-8.mol
Last updated:2024-10-23 13:36:13

Amino-PEG2-acid Properties

Boiling point 331.5±27.0 °C(Predicted)
Density 1.142±0.06 g/cm3(Predicted)
storage temp. Keep in dark place,Inert atmosphere,Room temperature
pka 4.27±0.10(Predicted)
form Solid
color White to off-white

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P280-P305+P351+P338
HS Code  2918999090

Amino-PEG2-acid price More Price(26)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC A577183 Amino-PEG2Acid 791028-27-8 10mg $45 2021-12-16 Buy
TRC A577183 Amino-PEG2Acid 791028-27-8 100mg $130 2021-12-16 Buy
Biosynth Carbosynth FP73006 3-(2-(2-Aminoethoxy)ethoxy)-propanoic acid 791028-27-8 250mg $160 2021-12-16 Buy
Biosynth Carbosynth FP73006 3-(2-(2-Aminoethoxy)ethoxy)-propanoic acid 791028-27-8 50mg $50 2021-12-16 Buy
Biosynth Carbosynth FP73006 3-(2-(2-Aminoethoxy)ethoxy)-propanoic acid 791028-27-8 100mg $80 2021-12-16 Buy
Product number Packaging Price Buy
A577183 10mg $45 Buy
A577183 100mg $130 Buy
FP73006 250mg $160 Buy
FP73006 50mg $50 Buy
FP73006 100mg $80 Buy

Amino-PEG2-acid Chemical Properties,Uses,Production

Description

Amino-PEG2-acid is a PEG reagent containing an amino group with a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.

Biological Activity

Amino-PEG2-C2-acid is a cleavable 3-unit PEG ADClinker for the synthesis of antibody-drug conjugated Ck (ADC). It is also a PEG-based PROTAClinker that can be used for PROTAC synthesis.

in vivo

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Amino-PEG2-acid Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 128)Suppliers
Supplier Tel Email Country ProdList Advantage
airuikechemical co., ltd.
+undefined86-15315557071 sales02@sdzhonghuimaterial.com China 983 58
9i LLC
+18039569191 MWan@NiNeiLab.com United States 418 58
Nanjing ChemLin Chemical Industry Co., Ltd.
025-83697070 product@chemlin.com.cn CHINA 3009 60
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795 ivan@atkchemical.com China 32957 60
career henan chemical co
+86-0371-86658258 +8613203830695 sales@coreychem.com China 29880 58
Accela ChemBio Inc.
+1-858-6993322 info@accelachem.com United States 17777 58
Chengdu Pukang Biotechnology Co., Ltd
028-82550498 export@pu-kang.com CHINA 210 58
Shandong chuangyingchemical Co., Ltd.
18853181302 sale@chuangyingchem.com CHINA 5906 58
Chongqing Chemdad Co., Ltd
+86-023-6139-8061 +86-86-13650506873 sales@chemdad.com China 39894 58
SHANGHAI T&W PHARMACEUTICAL CO., LTD.
+86-021-61551413 +8618813727289 contact@trustwe.com China 5738 58

View Lastest Price from Amino-PEG2-acid manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Amino-PEG2-C2-acid pictures 2024-10-24 Amino-PEG2-C2-acid
791028-27-8
US $0.00 / mg 10g TargetMol Chemicals Inc.
α-amine-ω-propionic acid diethylene glycol pictures 2024-10-15 α-amine-ω-propionic acid diethylene glycol
791028-27-8
US $0.00-0.00 / Kg 1Kg 99.9% 200tons airuikechemical co., ltd.
Amino-PEG2-COOH pictures 2024-03-23 Amino-PEG2-COOH
791028-27-8
US $0.00 / mg 250mg >98.00% 250mg Xian confluore Biological Technology Co., Ltd.
  • Amino-PEG2-COOH pictures
  • Amino-PEG2-COOH
    791028-27-8
  • US $0.00 / mg
  • >98.00%
  • Xian confluore Biological Technology Co., Ltd.
α-amine-ω-propionic acid diethylene glycol alpha-aMine-oMega-propionic acid diethylene glycol 3-[2-(2-Aminoethoxy)ethoxy]-propanoic acid Α-AMINE-Ω-PROPIONIC ACID DIETHYLENE GLYCOL Amino-PEG2-acid Amino-PEG2-propionic acid H2N-PEG2-CH2CH2COOH AMINE-PEG2-COOH Amino-PEG2-COOH Propanoic acid, 3-[2-(2-aminoethoxy)ethoxy]- H2N-(CH2CH2O)2-CH2CH2COOH H2N-PEG2-CH2CH2COOH NH2-PEG2-COOH Amino-PEG2-C2-acid α-Amine-ω-propionic acid diethylene glycol H2N-PEG2-CH2CH2COOH/Propanoic acid, 3-[2-(2-aminoethoxy)ethoxy]- 791028-27-8 PEG-COOtBu ADCs Linkers peg