Amino-PEG2-acid

Amino-PEG2-acid Suppliers list

Company Name:	airuikechemical co., ltd.
Tel:	+undefined86-15315557071
Email:	sales02@sdzhonghuimaterial.com
Products Intro:	Product Name:α-amine-ω-propionic acid diethylene glycol CAS:791028-27-8 Purity:99.9% Package:1Kg;0.00;USD\|5Kg;0.00;USD\|25Kg;0.00;USD

Company Name:	9i LLC
Tel:	+18039569191
Email:	MWan@NiNeiLab.com
Products Intro:	Product Name:α,ω-amine--propionic acid diethylene glycol CAS:791028-27-8 Purity:min.98% Package:225USD/1 g Remarks:NA563

Company Name:	Nanjing ChemLin Chemical Industry Co., Ltd.
Tel:	025-83697070
Email:	product@chemlin.com.cn
Products Intro:	CAS:791028-27-8 Purity:98% Package:g-Kg Remarks:Yellow oil

Company Name:	ATK CHEMICAL COMPANY LIMITED
Tel:	+undefined-21-51877795
Email:	ivan@atkchemical.com
Products Intro:	CAS:791028-27-8 Purity:98% Package:10MG;50MG;100MG,1G,5G,10G.100G

Company Name:	career henan chemical co
Tel:	+86-0371-86658258 +8613203830695
Email:	sales@coreychem.com
Products Intro:	Product Name:α-amine-ω-propionic acid diethylene glycol CAS:791028-27-8 Purity:97%-99% Package:1KG;8.8USD

Amino-PEG2-acid manufacturers

Amino-PEG2-acid Basic information

Product Name:	Amino-PEG2-acid
Synonyms:	α-amine-ω-propionic acid diethylene glycol;alpha-aMine-oMega-propionic acid diethylene glycol;3-[2-(2-Aminoethoxy)ethoxy]-propanoic acid;Α-AMINE-Ω-PROPIONIC ACID DIETHYLENE GLYCOL;Amino-PEG2-acid;Amino-PEG2-propionic acid;H₂N-PEG₂-CH₂CH₂COOH;AMINE-PEG2-COOH
CAS:	791028-27-8
MF:	C7H15NO4
MW:	177.2
EINECS:
Product Categories:	PEG-COOtBu;ADCs Linkers;peg
Mol File:	791028-27-8.mol

Amino-PEG2-acid Chemical Properties

Boiling point	331.5±27.0 °C(Predicted)
density	1.142±0.06 g/cm3(Predicted)
storage temp.	Keep in dark place,Inert atmosphere,Room temperature
pka	4.27±0.10(Predicted)
form	Solid
color	White to off-white

Safety Information

HS Code

2918999090

MSDS Information

Amino-PEG2-acid Usage And Synthesis

Description	Amino-PEG2-acid is a PEG reagent containing an amino group with a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.
Biological Activity	Amino-PEG2-C2-acid is a cleavable 3-unit PEG ADClinker for the synthesis of antibody-drug conjugated Ck (ADC). It is also a PEG-based PROTAClinker that can be used for PROTAC synthesis.
in vivo	ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Amino-PEG2-acid Preparation Products And Raw materials

Tag:Amino-PEG2-acid(791028-27-8) Related Product Information

α,ω-dipropionic acid tetraethylene glycol Biotin-PEG6-OH H2N-PEG8-tBu alpha-aMine-oMega-propionic acid triethylene glycol 5,8,11,14-Tetraoxa-2-azahexadecanedioic acid 2,5,8,11,14,17-Hexaoxanonadecan-19-amine MPEG16-NH2 TETRAETHYLENEGLYCOL MONOMETHYL ETHER N3-PEG3-tBu 2,5,8,11,14-Pentaoxahexadecan-16-amine 2,5,8,11,14,17,20,23,26,29,32,35-Dodecaoxaheptatriacontan-37-amine alpha-aMine-oMega-propionic acid dodecaethylene glycol HEPTAETHYLENE GLYCOL MONOMETHYL ETHER 2-[2-[2-[2-[2-[2-(BENZYLOXY)ETHOXY]ETHOXY]ETHOXY]ETHOXY]ETHOXY]ETHANOL 3,6,9,12,15-PENTAOXAHEPTADECANE-1,17-DIYL BIS-AMINE O-METHYL-UNDECAETHYLENE GLYCOL Carbamic acid, [2-(2-aminoethoxy)ethyl]-, 1,1-dimethylethyl ester (9CI) Amino-PEG4-acid