ChemicalBook >> CAS DataBase List >>Tigecycline Hydrochloride
Tigecycline Hydrochloride
- CAS No.
- 197654-04-9
- Chemical Name:
- Tigecycline Hydrochloride
- Synonyms
- Tigecycline Hydrochloride;Tigecycline monohydrochloride
- CBNumber:
- CB62502869
- Molecular Formula:
- C29H40ClN5O8
- Molecular Weight:
- 622.12
- MDL Number:
- MFCD18071372
- MOL File:
- 197654-04-9.mol
Last updated:2023-05-21 10:59:17
| storage temp. | Store at -20°C |
|---|---|
| solubility | Soluble in DMSO |
| form | Powder |
| FDA UNII | 7F4TZ17Y3R |
Tigecycline Hydrochloride price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| ApexBio Technology | B1219 | Tigecyclinehydrochloride | 197654-04-9 | 10mg | $135 | 2021-12-16 | Buy |
| ApexBio Technology | B1219 | Tigecyclinehydrochloride | 197654-04-9 | 50mg | $331 | 2021-12-16 | Buy |
| Crysdot | CD31002787 | Tigecyclinehydrochloride 98+% | 197654-04-9 | 10mg | $60 | 2021-12-16 | Buy |
| Crysdot | CD31002787 | Tigecyclinehydrochloride 98+% | 197654-04-9 | 50mg | $147 | 2021-12-16 | Buy |
| Crysdot | CD31002787 | Tigecyclinehydrochloride 98+% | 197654-04-9 | 100mg | $252 | 2021-12-16 | Buy |
Tigecycline Hydrochloride Chemical Properties,Uses,Production
Biological Activity
Tigecycline hydrochloride (GAR-936 hydrochloride) is a broad-spectrum glycylcycline antibiotic. The mean inhibitory concentration (MIC) of Tigecycline against E. coli (strain MG1655) is approximately 125 ng/mL. The MIC50 and MIC90 for Acinetobacter baumannii (A. baumannii) were 1 and 2 mg/L, respectively.
in vitro
Tigecycline (0.63-30 μM, preincubated for 4 days, treated for 72 h) inhibits AML2 cells and HL-60 cells with IC 50 s of 4.72±0.54 and 3.06±0.85 μM (freshly prepared).
in vivo
Tigecycline (50 mg/kg; intraperitoneal injection; twice a day; for 11 days) reduces tumor volume and weight in NOD/SCID mice.
target
Mean MIC: 125 ng/mL ( E. coli )
MIC50: 1 mg/mL ( A. baumannii )
MIC90: 2 mg/mL ( A. baumannii )
Tigecycline Hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
Tigecycline Hydrochloride Suppliers
Global( 13)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| Hangzhou MolCore BioPharmatech Co.,Ltd. | +86-057181025280; +8617767106207 | sales@molcore.com | China | 49739 | 58 |
| SPIRO PHARMA | eric_feng1954@126.com | China | 9254 | 55 | |
| Beijing Jin Ming Biotechnology Co., Ltd. | 010-60605840 18892239720 | psaitong@jm-bio.com | China | 12308 | 58 |
| Musechem | +1-800-259-7612 | info@musechem.com | United States | 4662 | 60 |
| Fan De(Beijing) Biotechnology Co., Ltd. | 15911056312 | liming@bio-fount.com | China | 9730 | 58 |
| MedBioPharmaceutical Technology Inc | 021-69568360 18916172912 | order@med-bio.cn | China | 8141 | 58 |
| Beijing Jin Ming Biotechnology Co., Ltd. | 010-60605840 | psaitong@jm-bio.com | China | 29778 | 58 |
| Shaanxi DIDU pharmaceutical and Chemical Co., Ltd | 15229059051 | 1027@dideu.com | China | 9967 | 58 |
| ApexBio Technology | -- | sales@apexbt.com | United States | 6254 | 58 |
Tigecycline Hydrochloride
Tigecycline monohydrochloride
197654-04-9
C29H40ClN5O8