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4-[(1-Methyl-1H-pyrrol-2-yl)methylene]-1,3(2H,4H)-isoquinolinedione

4-[(1-Methyl-1H-pyrrol-2-yl)methylene]-1,3(2H,4H)-isoquinolinedione structure

CAS No.: 1104546-89-5

Chemical Name:: 4-[(1-Methyl-1H-pyrrol-2-yl)methylene]-1,3(2H,4H)-isoquinolinedione

Synonyms: RT-017290;BYK 204165;PARP Inhibitor XIV;BYK204165 >=98% (HPLC);4-(1-methyl-1H-pyrrol-2-ylmethylene)-4H-isoquinolin-1,3-dione;4-(1-Methyl-1H-pyrrol-2-ylmethylene)-4H-isoquinoline-1,3-dione;4-((1-Methyl-1H-pyrrol-2-yl)methylene)isoquinoline-1,3(2H,4H)-dione;4-[(1-Methyl-1H-pyrrol-2-yl)methylene]-1,3(2H,4H)-isoquinolinedione;1,3(2H,4H)-Isoquinolinedione, 4-[(1-methyl-1H-pyrrol-2-yl)methylene]-;BYK-204165,poly ADP ribose polymerase,Inhibitor,PARP,antitumor,inhibit,BYK204165,BYK 204165

CBNumber:: CB62518783

Molecular Formula:: C15H12N2O2

Molecular Weight:: 252.27

MDL Number:: MFCD12912397

MOL File:: 1104546-89-5.mol

MSDS File:: SDS

Last updated:2023-06-08 09:02:50

Request For Quotation

4-[(1-Methyl-1H-pyrrol-2-yl)methylene]-1,3(2H,4H)-isoquinolinedione Properties

Boiling point	492.5±45.0 °C(Predicted)
Density	1.27±0.1 g/cm3(Predicted)
storage temp.	2-8°C
solubility	DMSO: >20mg/mL
pka	9.30±0.20(Predicted)
form	powder
color	yellow

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H317

Precautionary statements

P280

Hazard Codes

Risk Statements

Safety Statements

36/37

WGK Germany

NFPA 704

	0
2		0

4-[(1-Methyl-1H-pyrrol-2-yl)methylene]-1,3(2H,4H)-isoquinolinedione price More Price(25)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	B3188	BYK204165 ≥98% (HPLC)	1104546-89-5	5mg	$158	2024-03-01	Buy
Sigma-Aldrich	B3188	BYK204165 ≥98% (HPLC)	1104546-89-5	25mg	$493	2024-03-01	Buy
Cayman Chemical	21430	BYK204165 ≥98%	1104546-89-5	1mg	$37	2024-03-01	Buy
Cayman Chemical	21430	BYK204165 ≥98%	1104546-89-5	5mg	$142	2024-03-01	Buy
Sigma-Aldrich	528824	PARP Inhibitor XIV - CAS 1104546-89-5 - Calbiochem	1104546-89-5	10mg	$345	2024-03-01	Buy

Product number	Packaging	Price	Buy
B3188	5mg	$158	Buy
B3188	25mg	$493	Buy
21430	1mg	$37	Buy
21430	5mg	$142	Buy
528824	10mg	$345	Buy

4-[(1-Methyl-1H-pyrrol-2-yl)methylene]-1,3(2H,4H)-isoquinolinedione Chemical Properties,Uses,Production

Uses

BYK 204165 is an inhibitor of the poly(ADP-?ribose) polymerase (PARP), and it is 100-fold more selective for PARP-1.

Biochem/physiol Actions

BYK204165 is a potent and selective inhibitor of poly(ADP-ribose) polymerase 1 (PARP1). It is 100-fold selective for PARP-1 over PARP-2.

4-[(1-Methyl-1H-pyrrol-2-yl)methylene]-1,3(2H,4H)-isoquinolinedione Preparation Products And Raw materials

Raw materials

Preparation Products

4-[(1-Methyl-1H-pyrrol-2-yl)methylene]-1,3(2H,4H)-isoquinolinedione Suppliers

Global( 59)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32760	60
HANGZHOU CLAP TECHNOLOGY CO.,LTD	86-571-88216897,88216896 13588875226	sales@hzclap.com	CHINA	6313	58
InvivoChem	+1-708-310-1919 +1-13798911105	sales@invivochem.cn	United States	6393	58
TargetMol Chemicals Inc.	+1-781-999-5354	support@targetmol.com	United States	19973	58
Wuhan Topule Biopharmaceutical Co., Ltd	+8618327326525	masar@topule.com	China	8474	58
Aladdin Scientific	+1-+1(833)-552-7181	sales@aladdinsci.com	United States	57511	58
3B Pharmachem (Wuhan) International Co.,Ltd.	821-50328103-801 18930552037	3bsc@sina.com	China	15848	69
AdooQ BioScience, LLC	+1 (866) 930-6790	info@adooq.com	United States	2784	58
Sigma-Aldrich	021-61415566 800-8193336	orderCN@merckgroup.com	China	51471	80
EMMX Biotechnology LLC	888-539-0666	info@emmx.com	United States	8449	60

Supplier	Advantage
ATK CHEMICAL COMPANY LIMITED	60
HANGZHOU CLAP TECHNOLOGY CO.,LTD	58
InvivoChem	58
TargetMol Chemicals Inc.	58
Wuhan Topule Biopharmaceutical Co., Ltd	58
Aladdin Scientific	58
3B Pharmachem (Wuhan) International Co.,Ltd.	69
AdooQ BioScience, LLC	58
Sigma-Aldrich	80
EMMX Biotechnology LLC	60

4-[(1-Methyl-1H-pyrrol-2-yl)methylene]-1,3(2H,4H)-isoquinolinedione BYK 204165 4-(1-methyl-1H-pyrrol-2-ylmethylene)-4H-isoquinolin-1,3-dione PARP Inhibitor XIV 4-(1-Methyl-1H-pyrrol-2-ylmethylene)-4H-isoquinoline-1,3-dione RT-017290 1,3(2H,4H)-Isoquinolinedione, 4-[(1-methyl-1H-pyrrol-2-yl)methylene]- BYK204165 >=98% (HPLC) 4-((1-Methyl-1H-pyrrol-2-yl)methylene)isoquinoline-1,3(2H,4H)-dione BYK-204165,poly ADP ribose polymerase,Inhibitor,PARP,antitumor,inhibit,BYK204165,BYK 204165 1104546-89-5