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ChemicalBook >> CAS DataBase List >> 4-[(1-Methyl-1H-pyrrol-2-yl)methylene]-1,3(2H,4H)-isoquinolinedione

4-[(1-Methyl-1H-pyrrol-2-yl)methylene]-1,3(2H,4H)-isoquinolinedione

4-[(1-Methyl-1H-pyrrol-2-yl)methylene]-1,3(2H,4H)-isoquinolinedione price.
  • $37 - $1499
  • Product name: 4-[(1-Methyl-1H-pyrrol-2-yl)methylene]-1,3(2H,4H)-isoquinolinedione
  • CAS: 1104546-89-5
  • MF: C15H12N2O2
  • MW: 252.27
  • EINECS:
  • MDL Number:MFCD12912397
  • Synonyms:4-[(1-Methyl-1H-pyrrol-2-yl)methylene]-1,3(2H,4H)-isoquinolinedione;BYK 204165;4-(1-methyl-1H-pyrrol-2-ylmethylene)-4H-isoquinolin-1,3-dione;PARP Inhibitor XIV ;4-(1-Methyl-1H-pyrrol-2-ylmethylene)-4H-isoquinoline-1,3-dione;RT-017290;1,3(2H,4H)-Isoquinolinedione, 4-[(1-methyl-1H-pyrrol-2-yl)methylene]-;BYK204165 >=98% (HPLC)
Price25 Properties Safety Information Description
25 prices
Selected condition：
Brand
  • AK Scientific
  • Ambeed
  • ApexBio Technology
  • Cayman Chemical
  • ChemScene
  • CSNpharm
  • Sigma-Aldrich
  • TRC
  • Usbiological
Package
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • 1g
  • ManufacturerAK Scientific
  • Product number2830DC
  • Product description(4Z)-4-[(1-Methylpyrrol-2-yl)methylidene]isoquinoline-1,3-dione
  • Packaging1mg
  • Price$139
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number2830DC
  • Product description(4Z)-4-[(1-Methylpyrrol-2-yl)methylidene]isoquinoline-1,3-dione
  • Packaging5mg
  • Price$256
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA1219188
  • Product description4-((1-Methyl-1H-pyrrol-2-yl)methylene)isoquinoline-1,3(2H,4H)-dione 98%
  • Packaging5mg
  • Price$42
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA1219188
  • Product description4-((1-Methyl-1H-pyrrol-2-yl)methylene)isoquinoline-1,3(2H,4H)-dione 98%
  • Packaging10mg
  • Price$72
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA1219188
  • Product description4-((1-Methyl-1H-pyrrol-2-yl)methylene)isoquinoline-1,3(2H,4H)-dione 98%
  • Packaging25mg
  • Price$112
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA1219188
  • Product description4-((1-Methyl-1H-pyrrol-2-yl)methylene)isoquinoline-1,3(2H,4H)-dione 98%
  • Packaging50mg
  • Price$192
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA1219188
  • Product description4-((1-Methyl-1H-pyrrol-2-yl)methylene)isoquinoline-1,3(2H,4H)-dione 98%
  • Packaging100mg
  • Price$298
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA1219188
  • Product description4-((1-Methyl-1H-pyrrol-2-yl)methylene)isoquinoline-1,3(2H,4H)-dione 98%
  • Packaging250mg
  • Price$581
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA1219188
  • Product description4-((1-Methyl-1H-pyrrol-2-yl)methylene)isoquinoline-1,3(2H,4H)-dione 98%
  • Packaging1g
  • Price$1499
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA4525
  • Product descriptionBYK204165
  • Packaging10mg
  • Price$266
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA4525
  • Product descriptionBYK204165
  • Packaging50mg
  • Price$1095
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number21430
  • Product descriptionBYK204165 ≥98%
  • Packaging1mg
  • Price$37
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number21430
  • Product descriptionBYK204165 ≥98%
  • Packaging5mg
  • Price$142
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number21430
  • Product descriptionBYK204165 ≥98%
  • Packaging10mg
  • Price$195
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number21430
  • Product descriptionBYK204165 ≥98%
  • Packaging25mg
  • Price$442
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0029350
  • Product descriptionBYK204165 99.68%
  • Packaging5mg
  • Price$105
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 2830DC (4Z)-4-[(1-Methylpyrrol-2-yl)methylidene]isoquinoline-1,3-dione 1mg $139 2021-12-16 Buy
AK Scientific 2830DC (4Z)-4-[(1-Methylpyrrol-2-yl)methylidene]isoquinoline-1,3-dione 5mg $256 2021-12-16 Buy
Ambeed A1219188 4-((1-Methyl-1H-pyrrol-2-yl)methylene)isoquinoline-1,3(2H,4H)-dione 98% 5mg $42 2021-12-16 Buy
Ambeed A1219188 4-((1-Methyl-1H-pyrrol-2-yl)methylene)isoquinoline-1,3(2H,4H)-dione 98% 10mg $72 2021-12-16 Buy
Ambeed A1219188 4-((1-Methyl-1H-pyrrol-2-yl)methylene)isoquinoline-1,3(2H,4H)-dione 98% 25mg $112 2021-12-16 Buy
Ambeed A1219188 4-((1-Methyl-1H-pyrrol-2-yl)methylene)isoquinoline-1,3(2H,4H)-dione 98% 50mg $192 2021-12-16 Buy
Ambeed A1219188 4-((1-Methyl-1H-pyrrol-2-yl)methylene)isoquinoline-1,3(2H,4H)-dione 98% 100mg $298 2021-12-16 Buy
Ambeed A1219188 4-((1-Methyl-1H-pyrrol-2-yl)methylene)isoquinoline-1,3(2H,4H)-dione 98% 250mg $581 2021-12-16 Buy
Ambeed A1219188 4-((1-Methyl-1H-pyrrol-2-yl)methylene)isoquinoline-1,3(2H,4H)-dione 98% 1g $1499 2021-12-16 Buy
ApexBio Technology A4525 BYK204165 10mg $266 2021-12-16 Buy
ApexBio Technology A4525 BYK204165 50mg $1095 2021-12-16 Buy
Cayman Chemical 21430 BYK204165 ≥98% 1mg $37 2024-03-01 Buy
Cayman Chemical 21430 BYK204165 ≥98% 5mg $142 2024-03-01 Buy
Cayman Chemical 21430 BYK204165 ≥98% 10mg $195 2024-03-01 Buy
Cayman Chemical 21430 BYK204165 ≥98% 25mg $442 2024-03-01 Buy
ChemScene CS-0029350 BYK204165 99.68% 5mg $105 2021-12-16 Buy
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Properties

Boiling point :492.5±45.0 °C(Predicted)
Density :1.27±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: >20mg/mL
pka :9.30±0.20(Predicted)
form :powder
color :yellow

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H317 May cause an allergic skin reaction Sensitisation, Skin Category 1 Warning GHS hazard pictograms P261, P272, P280, P302+P352,P333+P313, P321, P363, P501
Precautionary statements:
P280 Wear protective gloves/protective clothing/eye protection/face protection.

Description

BYK204165, also known as PARP Inhibitor XIV, is a cell-permeable isoquinolinedione compound that potently and selectively inhibits poly (ADP-ribose) polymerase 1 (PARP1). PARP1 is a nuclear enzyme involved in the regulation of various cell processes such as differentiation, proliferation, and tumor transformation. It is also involved in the regulation of the molecular events involved in the recovery of cell from DNA damage. BYK204165’s potency is similar or higher than most current standard PARP-1 inhibitors (just slightly lower than PJ34), and it is 100-fold selective for PARP-1 over PARP-2.

Suppliers and manufacturers

ATK CHEMICAL COMPANY LIMITED
HANGZHOU CLAP TECHNOLOGY CO.,LTD
InvivoChem
TargetMol Chemicals Inc.
Wuhan Topule Biopharmaceutical Co., Ltd
Aladdin Scientific 3B Pharmachem (Wuhan) International Co.,Ltd. AdooQ BioScience, LLC Sigma-Aldrich EMMX Biotechnology LLC