HO-PEG10-tBu
- CAS No.
- 778596-26-2
- Chemical Name:
- HO-PEG10-tBu
- Synonyms
- PEG11-t-butly ester;HO-PEG10-CH2CH2COOtBu;OH-PEG10-TBA;HO-PEG10-tBu;HO-PEG10-COOtBu;Hydroxy-PEG10-Boc;OH-PEG10-CH2CH2COOtBu;Hydroxy-PEG10-t-butyl ester;Hydroxy-PEG10-t-butly ester;Hydroxy-PEG10-t-butyl ester,HO-PEG10-tBu
- CBNumber:
- CB62546894
- Molecular Formula:
- C27H54O13
- Molecular Weight:
- 586.71
- MDL Number:
- MFCD28385467
- MOL File:
- 778596-26-2.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() GHS07 |
---|---|
Signal word | Warning |
Hazard statements | H302-H315-H319-H335 |
Precautionary statements | P261-P305+P351+P338 |
HO-PEG10-tBu price
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Apolloscientific | BIPG1455 | Hydroxy-PEG10-t-butylester | 778596-26-2 | 100mg | $138 | 2021-12-16 | Buy |
BroadPharm | BP-22607 | Hydroxy-PEG10-t-butylester 98% | 778596-26-2 | 500mg | $200 | 2021-12-16 | Buy |
chempep | 280504 | HO-PEG10-tBu >=95% | 778596-26-2 | 1g | $305 | 2021-12-16 | Buy |
Apolloscientific | BIPG1455 | Hydroxy-PEG10-t-butylester | 778596-26-2 | 500mg | $435 | 2021-12-16 | Buy |
BroadPharm | BP-22607 | Hydroxy-PEG10-t-butylester 98% | 778596-26-2 | 2g | $450 | 2021-12-16 | Buy |
HO-PEG10-tBu Chemical Properties,Uses,Production
Description
Hydroxy-PEG10-t-butyl ester is a PEG linker containing a hydroxyl group with a t-butyl ester. The hydrophilic PEG spacer increases solubility in aqueous media. The hydroxyl group enables further derivatization or replacement with other reactive functional groups. The t-butyl protected carboxyl group can be deprotected under acidic conditions.
Uses
Hydroxy-PEG10-Boc is extacted from patent CN108707228 (example 0024)[1]. Hydroxy-PEG10-Boc is a uncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Hydroxy-PEG10-Boc can be conjugated to Paclitaxel (HY-B0015) or docetaxel (HY-B0011)[2].
References
[1] Huli, et al. A kind of preparation method of hydroxyl polyethylene glycol propionic ester. Patent CN108707228A.
[2] Miller ML, et al. Synthesis of taxoids with improved cytotoxicity and solubility for use in tumor-specific delivery.J Med Chem. 2004 Sep 23;47(20):4802-5. DOI:10.1021/jm049705s
HO-PEG10-tBu Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
9i LLC | +18039569191 | MWan@NiNeiLab.com | United States | 418 | 58 |
career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29808 | 58 |
SHANGHAI T&W PHARMACEUTICAL CO., LTD. | +86-021-61551413 +8618813727289 | contact@trustwe.com | China | 5738 | 58 |
Zhengzhou Alfa Chemical Co.,Ltd | +8618530059196 | sale04@alfachem.cn | China | 12162 | 58 |
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32159 | 58 |
Wuhan Borenpharm Co., Ltd | 027-65563561 18717150066 | 3207347307@qq.com | CHINA | 1238 | 58 |
Hangzhou Huarong Pharm Co., Ltd. | 571-86758373 +8613588754946 | sales@huarongpharm.com | CHINA | 3148 | 58 |
Nextpeptide Inc | +86-0571-81612335 +8613336028439 | sales@nextpeptide.com | China | 19908 | 58 |
Wuhan Topule Biopharmaceutical Co., Ltd | +8618327326525 | masar@topule.com | China | 8467 | 58 |
Changzhou AniKare Pharmatech Co., Ltd. | +86-0519-8359-8696 +8618018249389 | sales@anikare.com | China | 9875 | 58 |
View Lastest Price from HO-PEG10-tBu manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
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2024-03-25 | Hydroxy-PEG10-t-butyl ester
778596-26-2
|
US $0.00 / g | 1g | >98.00% | 1g | Xian confluore Biological Technology Co., Ltd. | |
![]() |
2020-03-06 | HO-PEG10-tBu
778596-26-2
|
US $2.00 / g | 1g | 95~99.9% | 5KG | Career Henan Chemical Co |
-
- Hydroxy-PEG10-t-butyl ester
778596-26-2
- US $0.00 / g
- >98.00%
- Xian confluore Biological Technology Co., Ltd.
-
- HO-PEG10-tBu
778596-26-2
- US $2.00 / g
- 95~99.9%
- Career Henan Chemical Co
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