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17-trifluoromethylphenyl trinor Prostaglandin F2α methyl ester

17-trifluoromethylphenyl trinor Prostaglandin F2α methyl ester Structure
17-trifluoromethylphenyl trinor Prostaglandin F2α methyl ester structure
CAS No.
195503-20-9
Chemical Name:
17-trifluoromethylphenyl trinor Prostaglandin F2α methyl ester
Synonyms
SPNWWFJGYHYDNY-HCAGXNQISA-N;17-trifluoromethylphenyl trinor Prostaglandin F2α methyl ester;17-trifluoromethylphenyl trinor Prostaglandin F2α methyl ester;17-trifluoromethylphenyl trinor Prostaglandin F2.alpha. methyl ester;17-trifluoromethylphenyl trinor Prostaglandin F2α methyl ester Exclusive;17-trifluoromethylphenyl trinor Prostaglandin F2α methyl ester Exclusive;5-Heptenoic acid, 7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3S)-3-hydroxy-5-[3-(trifluoromethyl)phenyl]-1-penten-1-yl]cyclopentyl]-, methyl ester, (5Z)-
CBNumber:
CB62589958
Molecular Formula:
C25H33F3O5
Molecular Weight:
470.52
MDL Number:
MOL File:
195503-20-9.mol
Last updated:2023-06-08 09:03:08
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17-trifluoromethylphenyl trinor Prostaglandin F2α methyl ester Properties

Boiling point 556.7±50.0 °C(Predicted)
Density 1.246±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMF: 25 mg/ml; DMSO: 50 mg/ml; Ethanol: 50 mg/ml; PBS (pH 7.2): .15 mg/ml
pka 14.25±0.20(Predicted)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictograms
GHS02,GHS07
Signal word  Danger
Hazard statements  H225-H319
Precautionary statements  P210-P233-P240-P241-P242-P243-P264-P280-P303+P361+P353-P305+P351+P338-P337+P313-P370+P378-P403+P235-P501
NFPA 704
3
2 0

17-trifluoromethylphenyl trinor Prostaglandin F2α methyl ester price More Price(5)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 10010111 17-trifluoromethylphenyl trinor Prostaglandin F2α methyl ester ≥98% 195503-20-9 1mg $59 2024-03-01 Buy
Cayman Chemical 10010111 17-trifluoromethylphenyl trinor Prostaglandin F2α methyl ester ≥98% 195503-20-9 5mg $253 2024-03-01 Buy
Cayman Chemical 10010111 17-trifluoromethylphenyl trinor Prostaglandin F2α methyl ester ≥98% 195503-20-9 10mg $448 2024-03-01 Buy
AK Scientific 6963DK Methyl7-[3,5-dihydroxy-2-[3-hydroxy-5-[3-(trifluoromethyl)phenyl]pent-1-enyl]cyclopentyl]hept-5-enoate 195503-20-9 10mg $596 2021-12-16 Buy
AK Scientific 6963DK Methyl7-[3,5-dihydroxy-2-[3-hydroxy-5-[3-(trifluoromethyl)phenyl]pent-1-enyl]cyclopentyl]hept-5-enoate 195503-20-9 1mg $162 2021-12-16 Buy
Product number Packaging Price Buy
10010111 1mg $59 Buy
10010111 5mg $253 Buy
10010111 10mg $448 Buy
6963DK 10mg $596 Buy
6963DK 1mg $162 Buy

17-trifluoromethylphenyl trinor Prostaglandin F2α methyl ester Chemical Properties,Uses,Production

Description

Prostaglandin F2α (PGF2α), acting through the FP receptor, causes smooth muscle contraction and exhibits potent luteolytic activity.1,2,3 17-trifluoromethylphenyl trinor PGF2α is an analog of PGF2α that shares the meta-trifluoromethyl group of travoprost with the 17-phenyl trinor modification of latanoprost. It is anticipated to be a potent and selective agonist of the FP receptor, with potential applications in glaucoma and luteolysis. 17-trifluoromethylphenyl trinor PGF2α methyl ester is a lipophilic analog of 17-trifluoromethylphenyl trinor PGF2α. Methyl esters of PGs serve as prodrugs, as they are efficiently hydrolyzed in certain tissues to generate the bioactive free acid.

References

1. Samuelsson, B., Goldyne, M., Granstr?m, E., et al. Prostaglandins and thromboxanes Annu. Rev. Biochem. 47,997-1029(1978).
2. Speroff, L., and Ramwell, P.W. Prostaglandins in reproductive physiology Am. J. Obstet. Gynecol. 107(7),1111-1130(1970).
3. Crankshaw, D.J., and Gaspar, V. Pharmacological characterization in vitro of prostanoid receptors in the myometrium of nonpregnant ewes J. Reprod. Fertil. 103(1),55-61(1995).

17-trifluoromethylphenyl trinor Prostaglandin F2α methyl ester Preparation Products And Raw materials

Raw materials

Preparation Products

17-trifluoromethylphenyl trinor Prostaglandin F2α methyl ester Suppliers

Global( 6)Suppliers
Supplier Tel Email Country ProdList Advantage
Shanghai Hongye Biotechnology Co. Ltd 400-9205774 sales@glpbio.cn China 6870 58
Hangzhou Synstar pharmaceutical Technology CO.,Ltd 0571-85361029 synstar518@163.com China 1991 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 8739 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 28091 58
Supplier Advantage
Shanghai Hongye Biotechnology Co. Ltd 58
Hangzhou Synstar pharmaceutical Technology CO.,Ltd 58
Shanghai Yifei Biotechnology Co. , Ltd. 58
TargetMol Chemicals Inc. 58
17-trifluoromethylphenyl trinor Prostaglandin F2α methyl ester 17-trifluoromethylphenyl trinor Prostaglandin F2α methyl ester Exclusive SPNWWFJGYHYDNY-HCAGXNQISA-N 17-trifluoromethylphenyl trinor Prostaglandin F2.alpha. methyl ester 17-trifluoromethylphenyl trinor Prostaglandin F2α methyl ester 17-trifluoromethylphenyl trinor Prostaglandin F2α methyl ester Exclusive 5-Heptenoic acid, 7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3S)-3-hydroxy-5-[3-(trifluoromethyl)phenyl]-1-penten-1-yl]cyclopentyl]-, methyl ester, (5Z)- 195503-20-9