ChemicalBook >> CAS DataBase List >>1,2-dipalMitoyl-sn-glycero-3-phosphoethanolaMine-N-[Methoxy(polyethylene glycol)-1000] (aMMoniuM sal

1,2-dipalMitoyl-sn-glycero-3-phosphoethanolaMine-N-[Methoxy(polyethylene glycol)-1000] (aMMoniuM sal

CAS No.
474922-84-4
Chemical Name:
1,2-dipalMitoyl-sn-glycero-3-phosphoethanolaMine-N-[Methoxy(polyethylene glycol)-1000] (aMMoniuM sal
Synonyms
16:0 PEG1000 PE;16:0 PEG2000 PE;16:0 PEG5000 PE;16:0 PEG3000 PE;16:0 PEG PE, MW 350;DipalmitoylphosphatidylethanolamineN-[methoxy(polyethylene glycol)-2000];1,2-dipalMitoyl-sn-glycero-3-phosphoethanolaMine-N-[Methoxy(polyethylene glycol)-1000] (aMMoniuM sal;1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000] (ammonium salt);alpha-[(9R)-6-Hydroxy-6-oxido-1,12-dioxo-9-[(1-oxohexadecyl)oxy]-5,7,11-trioxa-2-aza-6-phosphaheptacos-1-yl]-omega-methoxypoly(oxy-1,2-ethanediyl) ammonium salt
CBNumber:
CB62602464
Molecular Formula:
(C2H4O)n.C39H76NO10P.NH3
Molecular Weight:
0
MDL Number:
MFCD02262261
MOL File:
Mol file
Last updated:2024-07-02 08:55:13

1,2-dipalMitoyl-sn-glycero-3-phosphoethanolaMine-N-[Methoxy(polyethylene glycol)-1000] (aMMoniuM sal Properties

storage temp. -20°C
form Solid
color White to off-white

1,2-dipalMitoyl-sn-glycero-3-phosphoethanolaMine-N-[Methoxy(polyethylene glycol)-1000] (aMMoniuM sal Chemical Properties,Uses,Production

Description

16:0 PEG PE, MW 1,100 is a PEG-modified phospholipid conjugate used in liposome formation of sterically stabilized liposomes with low reticuloendothelial system uptake and increased circulation duration to target cells.

Uses

16:0 PEG3000 PE is suitable for the preparation of liposome and advanced drug delivery nano liposomal system.

Uses

16:0 PEG5000 PE or 1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-5000 has been used in preparation of lipid bilayer. It has also been used in liposome preparation.

Uses

16:0 PEG2000 PE, or 1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000] has been used in liposome preparation. It has also been used in preparation of tripeptide arginine-glycine-aspartic acid magnetoliposomes (RGD-MLPs) and poly(ethylene glycol) (PEG)- MLPs.

General Description

16:0 PEG5000 PE, also known as 1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-5000 (DPPE-PEG 5000), is a mPEG phospholipid conjugate. Poly(ethylene glycol) (PEG)-based liposomal formulations are widely used in preparation of biocompatible self-assembled drug-delivery systems. These systems have an ability to escape the recognition and uptake by cells in the immune system at the same time it extends the residence time of the liposomes and allows continuous drug release into the targeted cells.

Biochem/physiol Actions

Polyethylene glycol (PEG) conjugated phospholipids are useful in liposome formulation for maintaining their stereochemistry. They also serve as drug carriers. PEGylated lipids aid in the formation of mixed micelles at high concentration.

1,2-dipalMitoyl-sn-glycero-3-phosphoethanolaMine-N-[Methoxy(polyethylene glycol)-1000] (aMMoniuM sal Preparation Products And Raw materials

Raw materials

Preparation Products

1,2-dipalMitoyl-sn-glycero-3-phosphoethanolaMine-N-[Methoxy(polyethylene glycol)-1000] (aMMoniuM sal Suppliers

Global( 13)Suppliers
Supplier Tel Email Country ProdList Advantage
Creative Enzymes
1-516-855-7709 info@creative-enzymes.com United States 8748 58
Jilin Chinese Academy of Sciences-yanshen Technology
+undefined18143011203 info@chemextension.com China 42057 58
Shanghai T&W Pharmaceutical Co., Ltd. +86 21 61551611 China 9900 58
Sigma-Aldrich 021-61415566 800-8193336 orderCN@merckgroup.com China 51471 80
Shochem(Shanghai)Co.,Ltd +86-021-51783479 +86-13816874662 info@shochem.com China 301 58
Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd 0431-80514535 19917294565 et@chemextension.com China 5061 58
Guangzhou Weihua Biotechnology Co., Ltd 020-020-37239396 18922492046 weihuasw@foxmail.com China 2198 58
Suzhou Highfine Biotech Co., Ltd 0512-68417696 13962195629 qirl@highfine.com China 1383 58
Shanghai Easy CDMO Co.,Ltd 021-61734564 August@easycdmo.com China 10010 58
Shochem (Shanghai) Co.,Ltd 13611745246 13816874662 sales@shochem.com China 447 58
DipalmitoylphosphatidylethanolamineN-[methoxy(polyethylene glycol)-2000] 1,2-dipalMitoyl-sn-glycero-3-phosphoethanolaMine-N-[Methoxy(polyethylene glycol)-1000] (aMMoniuM sal alpha-[(9R)-6-Hydroxy-6-oxido-1,12-dioxo-9-[(1-oxohexadecyl)oxy]-5,7,11-trioxa-2-aza-6-phosphaheptacos-1-yl]-omega-methoxypoly(oxy-1,2-ethanediyl) ammonium salt 16:0 PEG3000 PE 16:0 PEG5000 PE 16:0 PEG2000 PE 16:0 PEG1000 PE 16:0 PEG PE, MW 350 1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000] (ammonium salt) 474922-84-4 C2H4OnC39H76NO10PNH3