1,2-dipalMitoyl-sn-glycero-3-phosphoethanolaMine-N-[Methoxy(polyethylene glycol)-1000] (aMMoniuM sal 化学特性,用途語,生産方法
使用
16:0 PEG5000 PE or 1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-5000 has been used in preparation of lipid bilayer. It has also been used in liposome preparation.
一般的な説明
16:0 PEG5000 PE, also known as 1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-5000 (DPPE-PEG 5000), is a mPEG phospholipid conjugate. Poly(ethylene glycol) (PEG)-based liposomal formulations are widely used in preparation of biocompatible self-assembled drug-delivery systems. These systems have an ability to escape the recognition and uptake by cells in the immune system at the same time it extends the residence time of the liposomes and allows continuous drug release into the targeted cells.
Biochem/physiol Actions
Polyethylene glycol (PEG) conjugated phospholipids are useful in liposome formulation for maintaining their stereochemistry. They also serve as drug carriers. PEGylated lipids aid in the formation of mixed micelles at high concentration.
1,2-dipalMitoyl-sn-glycero-3-phosphoethanolaMine-N-[Methoxy(polyethylene glycol)-1000] (aMMoniuM sal 上流と下流の製品情報
原材料
準備製品