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DIPROTIN A

DIPROTIN A structure

CAS No.: 90614-48-5

Chemical Name:: DIPROTIN A

Synonyms: Diprotin;DIPROTIN A;ILE-PRO-ILE;Ile-Pro-Ile-OH;DIPROTIN A H2O;ILE-PRO-ILE H2O;H-ILE-PRO-ILE-OH;H-ILE-PRO-ILE-OH H2O;L-Ile-L-Pro-L-Ile-OH;Diprotin A (Ile-Pro-Ile)

CBNumber:: CB6261540

Molecular Formula:: C17H31N3O4

Molecular Weight:: 341.45

MDL Number:: MFCD00038707

MOL File:: 90614-48-5.mol

MSDS File:: SDS

Last updated:2025-04-17 18:22:24

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DIPROTIN A Properties

Boiling point	583.1±50.0 °C(Predicted)
Density	1.140±0.06 g/cm3(Predicted)
storage temp.	-20°C
solubility	DMSO:250.0(Max Conc. mg/mL);732.17(Max Conc. mM) Water:67.08(Max Conc. mg/mL);196.44(Max Conc. mM)
pka	3.72±0.22(Predicted)
form	White to off-white solid.
color	White to off-white
Water Solubility	Soluble in water at 1mg/ml
CAS DataBase Reference	90614-48-5(CAS DataBase Reference)
EWG's Food Scores	1
UNSPSC Code	51111800
NACRES	NA.77

SAFETY

Risk and Safety Statements

WGK Germany	3
RTECS	NR4737000

DIPROTIN A price More Price(24)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	I9759	Ile-Pro-Ile ≥97% (HPLC)	90614-48-5	5mg	$171	2025-07-31	Buy
Sigma-Aldrich	I9759	Ile-Pro-Ile ≥97% (HPLC)	90614-48-5	25mg	$387	2025-07-31	Buy
TCI Chemical	D6199	Diprotin A	90614-48-5	50MG	$177	2025-07-31	Buy
Cayman Chemical	28014	Diprotin A	90614-48-5	10mg	$57	2024-03-01	Buy
Cayman Chemical	28014	Diprotin A	90614-48-5	25mg	$90	2024-03-01	Buy

Product number	Packaging	Price	Buy
I9759	5mg	$171	Buy
I9759	25mg	$387	Buy
D6199	50MG	$177	Buy
28014	10mg	$57	Buy
28014	25mg	$90	Buy

DIPROTIN A Chemical Properties,Uses,Production

Uses

Ile-Pro-Ile has been used as a supplement for blood collection for hormone measurement and used in Islets cell culture to stabilize glucagon-like peptide-1 (GLP-1). It has also been used to inhibit the breakdown of gonadotropin-inhibitory hormone (GnIH) following serum collection.

Uses

As New dipeptidyl peptidase IV inhibitors (Diprotin A) and their uses as anti-cancer agents

Definition

ChEBI: (2S,3S)-2-[[[(2S)-1-[(2S,3S)-2-amino-3-methyl-1-oxopentyl]-2-pyrrolidinyl]-oxomethyl]amino]-3-methylpentanoic acid is a peptide.

Biochem/physiol Actions

Inhibitor of dipeptidyl peptidase IV. Inhibits entry of HIV-1 or HIV-2 into T lymphoblastoid and monocytoid cell lines.

in vivo

Diprotin A (intraperitoneal injection; 70?μg/kg; twice daily; 7 days) increases the phosphorylation of Src and VE-cadherin and aggravates vascular leakage in the retinas. Collectively, Diprotin A induces vascular leakage by augmenting the SDF-1α/CXCR4/Src/VE-cadherin signaling pathway^[1].

Animal Model:	Streptozotocin-induced diabetic retinopathy model in wild-type C57/BL6 mice^[1]
Dosage:	70?μg/kg
Administration:	Intraperitoneal injection; twice daily; 7 days
Result:	Induced vascular leakage by augmenting the SDF-1α/CXCR4/Src/VE-cadherin signaling pathway.

IC 50

DPP-4

storage

Store at -20°C

DIPROTIN A Preparation Products And Raw materials

Raw materials

Preparation Products

DIPROTIN A Suppliers

Global( 135)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Adachibio Inc.	+8108027837258	sales@adachibio.com	Japan	992	58
Shenzhen Nexconn Pharmatechs Ltd	+86-755-89396905 +86-15013857715	admin@nexconn.com	China	10406	58
BOC Sciences	+1-631-485-4226	inquiry@bocsci.com	United States	19552	58
TargetMol Chemicals Inc.	+1-781-999-5354; +17819995354	marketing@targetmol.com	United States	32376	58
Career Henan Chemica Co	+86-0371-86658258 +8613203830695	laboratory@coreychem.com	China	30230	58
Dayang Chem (Hangzhou) Co.,Ltd.	+86-0571-88938639 +8617705817739	info@dycnchem.com	China	52846	58
Zhejiang J&C Biological Technology Co.,Limited	+1-2135480471	sales@sarms4muscle.com	China	10473	58
Nextpeptide Inc	+86-0571-81612335 +8613336028439	sales@nextpeptide.com	China	19908	58
Alfa Chemistry	+1-5166625404;	Info@alfa-chemistry.com	United States	20405	58
Chengdu Youngshe Chemical Co., Ltd.	+8618108235634	Cecilia@youngshechem.com	China	2345	58

Supplier	Advantage
Adachibio Inc.	58
Shenzhen Nexconn Pharmatechs Ltd	58
BOC Sciences	58
TargetMol Chemicals Inc.	58
Career Henan Chemica Co	58
Dayang Chem (Hangzhou) Co.,Ltd.	58
Zhejiang J&C Biological Technology Co.,Limited	58
Nextpeptide Inc	58
Alfa Chemistry	58
Chengdu Youngshe Chemical Co., Ltd.	58

View Lastest Price from DIPROTIN A manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2025-05-01	Diprotin A 90614-48-5	US $34.00-94.00 / mg		99.29%	10g	TargetMol Chemicals Inc.

Diprotin A
90614-48-5
US $34.00-94.00 / mg
99.29%
TargetMol Chemicals Inc.

90614-48-5(DIPROTIN A)Related Search:

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