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RO-32-0432

RO-32-0432 Structure
RO-32-0432 structure
CAS No.
151342-35-7
Chemical Name:
RO-32-0432
Synonyms
RO-32-0432;Ro 31-0432;RO 32-0432 HCL;RO 32-0432 HYDROCHLORIDE;BISINDOLYLMALEIMIDE XI, HCL;BISINDOLYLMALEIMIDE XL, HCL;BISINDOYLMALEIMIDE XI HYDROCHLORIDE;BISINDOLYLMALEIMIDE XI HYDROCHLORIDE;Ro 32 0432 hydrochloride,Ro 320432 hydrochloride;BisindolylMaleiMide XI . hydrochloride [Ro 32-0432]
CBNumber:
CB6262512
Molecular Formula:
C28H28N4O2
Molecular Weight:
452.55
MDL Number:
MFCD01319127
MOL File:
151342-35-7.mol
MSDS File:
SDS
Last updated:2024-10-28 16:48:35
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RO-32-0432 Properties

Boiling point 712.2±60.0 °C(Predicted)
Density 1.32±0.1 g/cm3(Predicted)
storage temp. −20°C
solubility DMSO: soluble
form solid
pka 7.91±0.60(Predicted)
color orange

SAFETY

Risk and Safety Statements

WGK Germany  3
HS Code  3822000000

RO-32-0432 price More Price(3)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Tocris 1587 Ro32-0432hydrochloride ≥99%(HPLC) 151342-35-7 1 $221 2021-12-16 Buy
Usbiological 044610 Bisindolylmaleimide XI Hydrochloride 151342-35-7 1mg $320 2021-12-16 Buy
ApexBio Technology B6798 Ro32-0432hydrochloride 151342-35-7 1mg $332 2021-12-16 Buy
Product number Packaging Price Buy
1587 1 $221 Buy
044610 1mg $320 Buy
B6798 1mg $332 Buy

RO-32-0432 Chemical Properties,Uses,Production

Uses

Bisindolylmaleimide XI is a potent and selective cell-permeable protein kinase C (PKC) inhibitor. Studies reveal that inhibition of PKCα by Bisindolylmaleimide XI and other similar PKC inhibitors has been associated with enhanced cardiac contractility and protection from heart failure. Bisindolylmaleimide XI has been shown to prevent T-cell activation and proliferation associated with chronic infl ammatory responses in vivo.

Biological Activity

Selective cell-permeable protein kinase C inhibitor. Displays slight selectivity for conventional PKC isoforms over Ca 2+ and atypical PKC isoforms; binding affinities for rat isoforms are 9, 28, 31, 37 and 108 nM for PKC's α , β Ι, β ΙΙ, γ and ε respectively. Orally available and prevents T-cell chronic inflammation in vivo .

RO-32-0432 Preparation Products And Raw materials

Raw materials

Preparation Products

RO-32-0432 Suppliers

Global( 54)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 32161 58
Career Henan Chemica Co 		+86-0371-86658258 +8613203830695 laboratory@coreychem.com China 30239 58
TargetMol Chemicals Inc. 		+8613564774135 zijue.cai@tsbiochem.com United States 19885 58
J & K SCIENTIFIC LTD. 010-82848833 400-666-7788 jkinfo@jkchemical.com China 96815 76
3B Pharmachem (Wuhan) International Co.,Ltd. 821-50328103-801 18930552037 3bsc@sina.com China 15839 69
Chemsky (shanghai) International Co.,Ltd 021-50135380 shchemsky@sina.com China 15402 60
EMMX Biotechnology LLC 888-539-0666 info@emmx.com United States 8447 60
Jinan Ruisi Pharmaceutical Technology Co., LTD 0531-69900633 18340090523 changyuan20@163.com China 2649 58
MedBioPharmaceutical Technology Inc 021-69568360 18916172912 order@med-bio.cn China 8140 58
TargetMol Chemicals Inc. 4008200310 marketing@tsbiochem.com China 24644 58
Supplier Advantage
TargetMol Chemicals Inc. 		58
Career Henan Chemica Co 		58
TargetMol Chemicals Inc. 		58
J & K SCIENTIFIC LTD. 76
3B Pharmachem (Wuhan) International Co.,Ltd. 69
Chemsky (shanghai) International Co.,Ltd 60
EMMX Biotechnology LLC 60
Jinan Ruisi Pharmaceutical Technology Co., LTD 58
MedBioPharmaceutical Technology Inc 58
TargetMol Chemicals Inc. 58

View Lastest Price from RO-32-0432 manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Ro 32-0432 hydrochloride pictures 2024-10-28 Ro 32-0432 hydrochloride
151342-35-7
 US $3100.00-1820.00 / mg 10g TargetMol Chemicals Inc.

151342-35-7(RO-32-0432)Related Search:

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RARECHEM AN KA 0813 RO-32-0432

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RO-32-0432 RO 32-0432 HCL RO 32-0432 HYDROCHLORIDE BISINDOLYLMALEIMIDE XI, HCL BISINDOLYLMALEIMIDE XI HYDROCHLORIDE BISINDOLYLMALEIMIDE XL, HCL BISINDOYLMALEIMIDE XI HYDROCHLORIDE 2-[8-[(DIMETHYLAMINO)METHYL]-6,7,8,9-TETRAHYDROPYRIDO[1,2-A]INDOL-3-YL]-3-(1-METHYL-1H-INDOL-3-YL)MALEIMIDE, HCL 2-(8-[(DIMETHYLAMINO)METHYL]-6,7,8,9-TETRAHYDROPYRIDO[1,2-A]INDOL-3-YL)-3-(1-METHYLINDOL-3-YL)MALEIMIDE HYDROCHLORIDE (S)-3-[8-[(Dimethylamino)methyl]-6,7,8,9-tetrahydropyrido[1,2-a]indol-10-yl]-4-(1-methyl-1H-indol-3-yl)-1H-pyrrole-2,5-dione 1H-Pyrrol-2,5-dione, 3-(8-((dimethylamino)methyl)-6,7,8,9-tetrahydropy rido(1,2-a)indol-10-yl)-4-(1-methyl-1H-indol-3-yl)-, (S)- Bisindoylmaleimide XI: 2-(8-[(Dimethylamino)methyl]-6,7,8,9-tetrahydropyrido[1,2-a]indol-3-yl)-3-(1-methylindol-3-yl)maleimide 3-[(8S)-8-[(Dimethylamino)methyl]-6,7,8,9-tetrahydropyrido[1,2-a]indol-10-yl]-4-(1-methyl-1H-indol-3-yl)-1H-pyrrole-2,5-dionehydrochloride 3-[8-[(DiMethylaMino)Methyl]-6,7,8,9-tetrahydropyrido[1,2-a]indol-10-yl]-4-(1-Methyl-1H-indol-3-yl)-1H-pyrrole-2,5-dione Hydrochloride Ro 31-0432 BisindolylMaleiMide XI . hydrochloride [Ro 32-0432] 1H-Pyrrole-2,5-dione, 3-[(8S)-8-[(dimethylamino)methyl]-6,7,8,9-tetrahydropyrido[1,2-a]indol-10-yl]-4-(1-methyl-1H-indol-3-yl)- Ro 32 0432 hydrochloride,Ro 320432 hydrochloride 151342-35-7 C28H28N4O2HCl C28H28N4O2ClH inhibitor