Dynasore hydrate
- CAS No.
- 1202867-00-2
- Chemical Name:
- Dynasore hydrate
- Synonyms
- Dynasore hydrate
- CBNumber:
- CB62750338
- Molecular Formula:
- C18H16N2O5
- Molecular Weight:
- 340.33004
- MDL Number:
- MFCD11045288
- MOL File:
- 1202867-00-2.mol
Dynasore hydrate price More Price(5)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | D7693 | Dynasore hydrate | 1202867-00-2 | 5mg | $120 | 2024-03-01 | Buy |
Sigma-Aldrich | D7693 | Dynasore hydrate | 1202867-00-2 | 25mg | $489 | 2024-03-01 | Buy |
American Custom Chemicals Corporation | INB0000994 | DYNASORE HYDRATE 95.00% | 1202867-00-2 | 10MG | $583 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | INB0000994 | DYNASORE HYDRATE 95.00% | 1202867-00-2 | 0.025G | $768 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | INB0000994 | DYNASORE HYDRATE 95.00% | 1202867-00-2 | 50MG | $1136 | 2021-12-16 | Buy |
Dynasore hydrate Chemical Properties,Uses,Production
Uses
Dynasore hydrate has been used:
- for priming fetal mesenchymal stem/stromal cells (fMSC)
- in confocal microscopy
- in wound healing/scratch and tube-formation assay
- to analyse its effects on Coxsackievirus A9 (CAV9) infection
- to inhibit clathrin-mediated endocytosis and caveolin-mediated endocytosis
- in live imaging of cells
General Description
Dynasore is a small molecule GTPase inhibitor that targets dynamin-1, dynamin-2 and Drp1 (mitochondrial). Dynasore blocks dynamin-dependent endocytosis, scission of endocytic vesicles. Dynosore is profibrotic, induces PAI-1 in pleural mesothelial cells, and may be an effective pleurodesing (pleurodesis) agent. Dynasor blocks human papillomavirus type 16 (HPV16) and bovine papillomavirus type 1 (BPV1) (pseudovirions) infections.
Dynasore hydrate lowers labile cholesterol in the plasma membrane and distorts lipid raft organization. Dynasore exhibits pleotropic effects on herpes simplex virus (HSV)-1 and HSV-2 infection. It hinders viral entry, trafficking of viral proteins and capsid formation.
Biochem/physiol Actions
Dynasore is a cell-permeable, reversible noncompetitive dynamin 1 and dynamin 2 GTPase activity inhibitor.
Dynasore hydrate Preparation Products And Raw materials
Raw materials
Preparation Products
Dynasore hydrate Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51471 | 80 |
Energy Chemical | 021-58432009 400-005-6266 | marketing@energy-chemical.com | China | 44941 | 58 |
Supplier | Advantage |
---|---|
Sigma-Aldrich | 80 |
Energy Chemical | 58 |