Ceftezole
- CAS No.
- 26973-24-0
- Chemical Name:
- Ceftezole
- Synonyms
- CTZ;CG-B 3Q;FR 10123;Celoslin;ceftezol;CEFTEZOLE;CEPHTEZOL;Ceftazole;NSC 102805;Ceftezole Acid
- CBNumber:
- CB6277787
- Molecular Formula:
- C13H12N8O4S3
- Molecular Weight:
- 440.48
- MDL Number:
- MFCD00274176
- MOL File:
- 26973-24-0.mol
- MSDS File:
- SDS
| Melting point | 155°C (dec.) |
|---|---|
| Density | 2.09 |
| storage temp. | Store at -20°C |
| solubility | DMSO: 88 mg/mL (199.78 mM);; |
| pka | 2.60±0.50(Predicted) |
| λmax | 273nm(Phosphate buffer sol.)(lit.) |
| Merck | 14,1948 |
| CAS DataBase Reference | 26973-24-0(CAS DataBase Reference) |
| FDA UNII | 2Z86SYP11W |
| ATC code | J01DB12 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS07,GHS09 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302+H312+H332-H410 |
| Precautionary statements | P261-P273-P280-P301+P312-P302+P352+P312-P304+P340+P312 |
| Hazard Codes | T+,N |
| Risk Statements | 21/22-26-50/53 |
| Safety Statements | 28-36/37-45-61 |
Ceftezole price More Price(11)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 716707 | Cadmium zinc telluride 99.9999% trace metals basis | 26973-24-0 | 5g | $146 | 2023-01-07 | Buy |
| TRC | C244315 | Ceftezole | 26973-24-0 | 10g | $85 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FC41103 | Ceftezole | 26973-24-0 | 5G | $90 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FC41103 | Ceftezole | 26973-24-0 | 10g | $144 | 2021-12-16 | Buy |
| AK Scientific | J11705 | Ceftezole | 26973-24-0 | 25mg | $38 | 2021-12-16 | Buy |
Ceftezole Chemical Properties,Uses,Production
Originator
Ceftezole,Arocor Holdings Inc.
Uses
Ceftezole is a β-lactam, cephem antibiotic. It also exhibits potent α-glucosidase inhibitory activity and antidiabetic effect in streptozotocin-induced mouse.
Uses
A direct bandgap semiconductor, it is used in a variety of applications, including radiation detectors, photorefractive gratings, electro-optic modulators, solar cells, and terahertz generation and detection. The band gap varies from approximately 1.4 to 2.2 eV, depending on composition.
Definition
ChEBI: Ceftezole is a first-generation cephalosporin antibiotic having (1,3,4-thiadiazol-2-ylsulfanyl)methyl and [2-(1H-tetrazol-1-yl)acetamido side groups located at positions 3 and 7 respectively. It is a cephalosporin and a member of thiadiazoles.
Manufacturing Process
To a solution of 1 equivalent (eq.) of 1H-tetrazole-1-acetic acid and 1 eq. of
triethylamine in 20 ml of tetrahydrofuran cooled to -20°C was added 1 eq. of
pivaloyl chloride. After thirty-minute stirring of the mixture 20 ml of a
chloroform solution containing 1 eq. of and 1 eq. of triethylamine was poured
into the solution cooled at -10°C during a period of 30 minutes. The resulting
mixed solution was stirred for 30 minutes at the same temperature, for 1 hour
in an ice-water mixture and for 3 hours at room temperature. Removal of a
solvent from the reaction mixture afforded an oily residue, which was
dissolved into 15 ml of 10% sodium bicarbonate aqueous solution. The
resulting aqueous layer was adjusted to pH 1.0-2.0 with 10% hydrochloric
acid, washed with ether and extracted with ethyl acetate. The extract was
washed with water, dried over sodium sulfate and concentrated under reduced
pressure leaving a residue which was triturated with ethyl acetate to obtain 3-
acetoxymethyl-8-oxo-7-(2-tetrazol-1-acetylamino)-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid.
A solution of 1 eq. of sodium salt of 3-acetoxymethyl-8-oxo-7-(2-tetrazol-1-
acetylamino)-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid (it may be
prepared with equivalent of sodium bicarbonate and above named acid) and 1
eq. of [1.3.4]-thiadiazole-2-thiol in 20 ml of phosphate buffer (pH 6.4) was
stirred for 5.5 hours at 60°C. The reaction mixture was adjusted to pH 2.0
with 5% hydrochloric acid and treated with ethyl acetate to form a title
compound - ceftezole.
Therapeutic Function
Antibiotic
General Description
Cadmium zinc telluride (Cd1-xZnxTe or CZT) can detect nuclear radiation hence, CZT with Zn concentrations between 0.1-0.2 may be used in the making of radiation detectors of X-ray and gamma-ray spectrometers.
Ceftezole Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21634 | 55 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29880 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | sales@chemdad.com | China | 39894 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49374 | 58 |
| SIMAGCHEM CORP | +86-13806087780 | sale@simagchem.com | China | 17365 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32161 | 58 |
| Longyan Tianhua Biological Technology Co., Ltd | 0086 18039857276 18039857276 | CHINA | 2783 | 58 | |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34563 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-029-89586680 +86-18192503167 | 1026@dideu.com | China | 7724 | 58 |
| AFINE CHEMICALS LIMITED | +86-0571-85134551 | sales@afinechem.com | China | 15352 | 58 |
View Lastest Price from Ceftezole manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2021-07-13 | Ceftezole
26973-24-0
|
US $15.00-10.00 / KG | 1KG | 99%+ HPLC | Monthly supply of 1 ton | Zhuozhou Wenxi import and Export Co., Ltd | |
 |
2021-07-10 | Ceftezole
26973-24-0
|
US $15.00-10.00 / KG | 1KG | 99%+ HPLC | Monthly supply of 1 ton | Zhuozhou Wenxi import and Export Co., Ltd | |
 |
2020-05-25 | Ceftezole
26973-24-0
|
US $0.00-0.00 / Kg | 1KG | 99.0%+ | 300 MT | Shaanxi Dideu Medichem Co. Ltd |