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BUSERELIN

BUSERELIN structure

CAS No.: 57982-77-1

Chemical Name:: BUSERELIN

Synonyms: hoe766a;receptal;Suprefact;BUSERELIN;Buserilin;etilamide;ici123215;Buserelin CRS;Buserelina(net);BUSERELIN PH. EUR.

CBNumber:: CB6287694

Molecular Formula:: C60H86N16O13

Molecular Weight:: 1239.42

MDL Number:: MFCD00870371

MOL File:: 57982-77-1.mol

MSDS File:: SDS

Last updated:2023-11-24 16:35:22

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BUSERELIN Properties

alpha	D20 -40.4° (c = 1 in dimethylacetamide)
Boiling point	845.19°C (rough estimate)
Density	1.0711 (rough estimate)
refractive index	1.6200 (estimate)
solubility	Sparingly soluble in water and in dilute acids.
pka	9.82±0.15(Predicted)
form	Solid
color	White to Off-White
Stability	Hygroscopic
InChIKey	CUWODFFVMXJOKD-UHFFFAOYSA-N
NCI Dictionary of Cancer Terms	buserelin
FDA UNII	PXW8U3YXDV
NCI Drug Dictionary	buserelin
ATC code	L02AE01

Pharmacokinetic data

Protein binding	151%
Excreted unchanged in urine	30 (SC), <1 (intranasal)2%
Biological half-life	80 minutes / -

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07,GHS08
Signal word	Danger
Hazard statements	H302-H360F
Precautionary statements	P308+P313
HS Code	2937190000

BUSERELIN price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Biosynth Carbosynth	FD109219	(Des-Gly10,D-Ser(tBu)6,Pro-NHEt 9)-LHRH acetate salt Pyr-His-Trp-Ser-Tyr-D-Ser(tBu)-Leu-Arg-Pro-NHEt acetate salt	57982-77-1	5mg	$131	2021-12-16	Buy
Biosynth Carbosynth	FD109219	(Des-Gly10,D-Ser(tBu)6,Pro-NHEt 9)-LHRH acetate salt Pyr-His-Trp-Ser-Tyr-D-Ser(tBu)-Leu-Arg-Pro-NHEt acetate salt	57982-77-1	10mg	$228	2021-12-16	Buy
American Custom Chemicals Corporation	API0005431	BUSERELIN 95.00%	57982-77-1	1MG	$242.55	2021-12-16	Buy
Apolloscientific	BITH3005	Buserelin	57982-77-1	5mg	$399	2021-12-16	Buy
Biosynth Carbosynth	FD109219	(Des-Gly10,D-Ser(tBu)6,Pro-NHEt 9)-LHRH acetate salt Pyr-His-Trp-Ser-Tyr-D-Ser(tBu)-Leu-Arg-Pro-NHEt acetate salt	57982-77-1	25mg	$456	2021-12-16	Buy

Product number	Packaging	Price	Buy
FD109219	5mg	$131	Buy
FD109219	10mg	$228	Buy
API0005431	1MG	$242.55	Buy
BITH3005	5mg	$399	Buy
FD109219	25mg	$456	Buy

BUSERELIN Chemical Properties,Uses,Production

Description

Buserelin (Suprefact?) is a hormonal therapy drug used to treat advanced prostate cancer. It is a medication which is used primarily in the treatment of prostate cancer and endometriosis. It is also used for other indications such as the treatment of premenopausal breast cancer, uterine fibroids, and early puberty, in assisted reproduction for female infertility, and as a part of transgender hormone therapy. In addition, buserelin is used in veterinary medicine. The medication is typically used as a nasal spray three times per day, but is also available for use as a solution or implant for injection into fat.

Chemical Properties

White or slightly yellowish powder, hygroscopic.

Uses

Gonad-stimulating principle.

Definition

ChEBI: Buserelin is an oligopeptide.

brand name

Suprefact (Hoechst-Roussel).

Clinical Use

Treatment of advanced prostate cancer and endometriosis

Pituitary desensitisation in preparation for ovulation induction regimens using gonadotrophins

Side effects

Using too much Buserelin Injection may make you feel weak, nervous, dizzy and sick. You may also have a headache, hot flushes, stomach pain, swelling of the legs and breast pain. You may also have pain, bleeding or hardening of the skin at the site of injection

Metabolism

Metabolic inactivation by peptides occurs in the liver and kidney. The drug is also inactivated by pituitary membrane enzymes. Excreted in the urine and bile as unchanged drug and metabolites.

BUSERELIN Preparation Products And Raw materials

Raw materials

Preparation Products

BUSERELIN Suppliers

Global( 155)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Chengdu Youngshe Chemical Co., Ltd.	+8618108235634	Cecilia@youngshechem.com	China	2345	58
Apextide Co Ltd	+86-15300650552 +86-15300650552	info@apextide.com	China	92	58
Shandong Huisheng Import & Export Co., Ltd.	+86-13176845580 +86-13176845580	da@zhongda-biotech.com	China	232	58
Nantong Guangyuan Chemicl Co,Ltd	+undefined17712220823	admin@guyunchem.com	China	615	58
Hebei Yanxi Chemical Co., Ltd.	+8617531153977	allison@yan-xi.com	China	5856	58
Anhui Zhongda Biotechnology Co., Ltd	+8619956560829	justine@zhongda-biotech.com	China	286	58
Anhui Zhongda Biotechnology Co., Ltd	+8615689548120	linda@zhongda-biotech.com	China	193	58
Anhui Ruihan Technology Co., Ltd	+8617756083858	daisy@anhuiruihan.com	China	973	58
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29879	58
Shenzhen Nexconn Pharmatechs Ltd	+86-755-89396905 +86-15013857715	admin@nexconn.com	China	10311	58

Supplier	Advantage
Chengdu Youngshe Chemical Co., Ltd.	58
Apextide Co Ltd	58
Shandong Huisheng Import & Export Co., Ltd.	58
Nantong Guangyuan Chemicl Co,Ltd	58
Hebei Yanxi Chemical Co., Ltd.	58
Anhui Zhongda Biotechnology Co., Ltd	58
Anhui Zhongda Biotechnology Co., Ltd	58
Anhui Ruihan Technology Co., Ltd	58
career henan chemical co	58
Shenzhen Nexconn Pharmatechs Ltd	58

View Lastest Price from BUSERELIN manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2025-01-06	BUSERELIN 57982-77-1	US $840.00 / g	1g	99%	1kg	Baoji Guokang Bio-Technology Co., Ltd.
2024-10-25	BUSERELIN 57982-77-1	US $40.00 / kg	1kg	0.99	10 tons	Hebei Yanxi Chemical Co., Ltd.
2024-10-23	BUSERELIN 57982-77-1	US $9.90-9.90 / g	1g	99%	100kg	Wuhan Cell Pharmaceutical Co., Ltd

BUSERELIN
57982-77-1
US $840.00 / g
99%
Baoji Guokang Bio-Technology Co., Ltd.

BUSERELIN
57982-77-1
US $40.00 / kg
0.99
Hebei Yanxi Chemical Co., Ltd.

BUSERELIN
57982-77-1
US $9.90-9.90 / g
99%
Wuhan Cell Pharmaceutical Co., Ltd

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(d-ser(bu(supt)(sup6)))-lh-rh(1-9)nonapeptide-ethylamide (d-ser(tbu)(sup6)-ea(sup10))-lhrh (d-ser(tbu)(sup6)-ea(sup10))-luteinizinghormone-releasinghormon (d-ser(tbu)(sup6)-ea(sup10))-luteinizinghormone-releasinghormone BUSERELIN 1-9-Luteinizing hormone-releasing factor (swine), 6-[O-(1,1-dimethylethyl)-D-serine]-9-(N-ethyl-L-prolinamide)- Buserilin BUSERELIN PH. EUR. Pyr-His-Trp-Ser-Tyr-D-Ser(tBu)-Leu-Arg-Pro-NHEt acetate salt Suprefact d-ser(tbu(sup6))-lh-rh-(1-9)-nonapeptideethylamide d-ser-(tbu)(sup6)-lhrh-ethylamide etilamide ici123215 luteinizinghormone-releasinghormone(pig),6-(o-(1,1-dimethylethyl)-d-serine) receptal P-GLU-HIS-TRP-SER-TYR-D-SER(TBU)-LEU-ARG-PRO-NHET PYR-HIS-TRP-SER-TYR-D-SER(TBU)-LEU-ARG-PRO-NHET (DES-GLY10,D-SER(TBU)6,PRO-NHET9)-LHRH Buserilin,1-9-Luteinizing hormone-releasing factor (swine), 6-[O-(1,1-dimethylethyl)-D-serine]-9-(N-ethyl-L-prolinamide)- (Des-Gly10,D-Ser(tBu)6,Pro-NHEt 9)-LHRH acetate salt Pyr-His-Trp-Ser-Tyr-D-Ser(tBu)-Leu-Arg-Pro-NHEt acetate salt (2S)-N-[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2R)-1-[[(2S)-1-[[(2S)-5-(diaminomethylideneamino)-1-[(2S)-2-(ethylcarbamoyl)-1-pyrrolidinyl]-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-[(2 Buserelin CRS BuserelinQ: What is Buserelin Q: What is the CAS Number of Buserelin Q: What is the storage condition of Buserelin Buserelina(net) (2S)-N-[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2R)-1-[[(2S)-1-[[(2S)-5-(diaminomethylideneamino)-1-[(2S)-2-(ethylcarbamoyl)pyrrolidin-1-yl]-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-[(2-methylpropan-2-yl)oxy]-1-oxopropan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]-5-oxopyrrolidine-2-carboxamide Buserelin, Buserelina hoe766a 57982-77-1 C60H86N16O13 BioChemical Amino Acids and Peptides Biochemicals and Reagents Releasing Factors Peptides LH-RH hormones 57982-77-1