CLOSTRIDIUM DIFFICILE TOXIN A
- CAS No.
- Chemical Name:
- CLOSTRIDIUM DIFFICILE TOXIN A
- Synonyms
- CLOSTRIDIUM DIFFICILE TOXIN A
- CBNumber:
- CB6295118
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MFCD02098001
- MOL File:
- Mol file
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS06 |
|---|---|
| Symbol(GHS) | GHS06 |
| Signal word | Danger |
| Signal word | Danger |
| Hazard statements | H301-H312+H332 |
| Hazard statements | H301-H312+H332 |
| Precautionary statements | P261-P264-P280-P301+P310-P302+P352+P312-P304+P340+P312 |
| Precautionary statements | P261-P264-P280-P301+P310-P302+P352+P312-P304+P340+P312 |
| Hazard Codes | T+ |
| Risk Statements | 26/27/28-36/37/38 |
| Safety Statements | 26-36/37/39-45 |
| RIDADR | UN 3462 6.1/PG 1 |
| WGK Germany | 3 |
CLOSTRIDIUM DIFFICILE TOXIN A price More Price(8)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | SML1154 | Clostridium difficile Toxin A ≥95% (SDS-PAGE) | 2μG | $433 | 2023-06-20 | Buy | |
| Sigma-Aldrich | SML1154 | Clostridium difficile Toxin A ≥95% (SDS-PAGE) | 50μG | $639 | 2023-06-20 | Buy | |
| Usbiological | 470521 | Clostridium Difficile Toxin A | 1mg | $914 | 2021-12-16 | Buy | |
| Usbiological | 397619 | Clostridium Difficile Toxin A | 50ug | $519 | 2021-12-16 | Buy | |
| Usbiological | 470529 | Clostridium difficile Toxin A | 1mg | $618 | 2021-12-16 | Buy |
CLOSTRIDIUM DIFFICILE TOXIN A Chemical Properties,Uses,Production
General Description
Native toxin A purified from C. difficile strain VPI10463 (toxinotype 0)
Biochem/physiol Actions
Clostridium difficile Toxin A and B, cation-dependent UDP-glucose glucosyltransferases, are cellular toxins that inactivate Rho (and Rho family small GTPases) through monoglucosylation of these family members. TcdA elicits effects primarily within the intestinal epithelium. Effects of this monoglucosylation include disregulation of the actin cytoskeleton, cell rounding, cytotoxicity, and altered cellular signaling. Rho proteins are monoglucosylated by Toxin A and B using UDP-glucose as a cosubstrate. Rho, Rac and Cdc42 are included in the Rho subfamilies targeted by both toxins. Low molecular mass GTP-binding proteins that are not modified by Toxin A and B include Ras, Rab, Arf, or Ran subfamilies as well as heterotrimeric G proteins.
CLOSTRIDIUM DIFFICILE TOXIN A Preparation Products And Raw materials
Raw materials
Preparation Products
CLOSTRIDIUM DIFFICILE TOXIN A Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51471 | 80 |
| Supplier | Advantage |
|---|---|
| Sigma-Aldrich | 80 |