ANTI-8-HYDROXYGUANOSINE
- CAS No.
- Chemical Name:
- ANTI-8-HYDROXYGUANOSINE
- Synonyms
- Anti-8OHG;ANTI-8OHDG;ANTI-8-OHG GOAT PAB;Anti-DNA/RNA Damage;ANTI-8-OXO-G GOAT PAB;ANTI-8-HYDROXYGUANOSINE;ANTI-8-HYDROXYGUANOSINE GOAT PAB;Monoclonal Anti-DNA/RNA Damage antibody produced in mouse
- CBNumber:
- CB6298179
- Molecular Formula:
- C10H13N5O6
- Molecular Weight:
- 299.24012
- MDL Number:
- MFCD04040135
- MOL File:
- Mol file
ANTI-8-HYDROXYGUANOSINE price More Price(2)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | DR1001 | Anti-8-Hydroxyguanosine Goat pAb liquid, Calbiochem? | 100μL | $458 | 2024-03-01 | Buy | |
| Sigma-Aldrich | SAB5200010 | Monoclonal Anti-DNA/RNA Damage antibody produced in mouse clone 15A3, 1?mg/mL, purified immunoglobulin | 100μG | $503 | 2023-06-20 | Buy |
ANTI-8-HYDROXYGUANOSINE Chemical Properties,Uses,Production
General Description
DNA/RNA damage, also known as 8-hydroxyguanine (8-OHG), is a product of oxidized DNA or RNA.
Biochem/physiol Actions
8-hydroxyguanine (8-OHG) helps in determining the reactive oxygen species (ROS)-induced modification of a purine residue in DNA. It is a sensitive marker of oxidative DNA damage. Overexpression of the gene has been observed in diabetic patients, especially those with advanced microvascular complications. Thus, 8-OHG functions as a novel biomarker for identifying oxidative DNA damage in diabetic patients. Plasma level of 8-OHG elevates with the age, with cigarette smoking and during tumorigenesis. 8-OHG levels in urine is considered as a biomarker of the total systemic oxidative stress in vivo. Overexpression of 8-OHG has been observed in various neurodegenerative diseases such as Parkinson′s disease (PD) and multiple system atrophy (MSA).
ANTI-8-HYDROXYGUANOSINE Preparation Products And Raw materials
Raw materials
Preparation Products
ANTI-8-HYDROXYGUANOSINE Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Riedel-de Haen AG | -- | United States | 6825 | 87 | |
| EMD Biosciences, Inc. | -- | technical@calbiochem.com | United States | 6529 | 66 |
| Alexis Corporation | -- | alexis-ch@alexis-corp.ch | Switzerland | 3599 | 74 |
| BIODESIGN International/OEM Concepts | -- | info@biodesign.com | United States | 2376 | 50 |
| Supplier | Advantage |
|---|---|
| Riedel-de Haen AG | 87 |
| EMD Biosciences, Inc. | 66 |
| Alexis Corporation | 74 |
| BIODESIGN International/OEM Concepts | 50 |