ChemicalBook >> CAS DataBase List >>Ethyl (2R,4S)-4-([1,1'-biphenyl]-4-ylmethyl)-2-methyl-4-(2,5-dioxopyrrolidin-1-yl)butanoate

Ethyl (2R,4S)-4-([1,1'-biphenyl]-4-ylmethyl)-2-methyl-4-(2,5-dioxopyrrolidin-1-yl)butanoate

CAS No.
1038924-97-8
Chemical Name:
Ethyl (2R,4S)-4-([1,1'-biphenyl]-4-ylmethyl)-2-methyl-4-(2,5-dioxopyrrolidin-1-yl)butanoate
Synonyms
LCZ700;LCZ696-9;LCZ-696-006-RS;LCZ-696-006-2R4S;LCZ-696 Impurity 4;Sakubiter Impurity 2;Valsartan Impurity 77;SACUBITRIL SUCCINIMIDE;LCZ-696 Impurity 550-06;Salcubatra calcium impurity P
CBNumber:
CB62995782
Molecular Formula:
C24H27NO4
Molecular Weight:
393.48
MDL Number:
MFCD34597455
MOL File:
1038924-97-8.mol
MSDS File:
SDS
Last updated:2023-05-15 10:44:00

Ethyl (2R,4S)-4-([1,1'-biphenyl]-4-ylmethyl)-2-methyl-4-(2,5-dioxopyrrolidin-1-yl)butanoate Properties

Boiling point 581.3±50.0 °C(Predicted)
Density 1.166±0.06 g/cm3(Predicted)
solubility Chloroform (Sparingly), Ethyl Acetate (Slightly)
form Solid
pka -1.52±0.20(Predicted)
color White to Off-White Waxy

Ethyl (2R,4S)-4-([1,1'-biphenyl]-4-ylmethyl)-2-methyl-4-(2,5-dioxopyrrolidin-1-yl)butanoate price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC D486550 2,5-DioxopyrrolidineSacubitril 1038924-97-8 5mg $290 2021-12-16 Buy
TRC D486550 2,5-DioxopyrrolidineSacubitril 1038924-97-8 25mg $1210 2021-12-16 Buy
Product number Packaging Price Buy
D486550 5mg $290 Buy
D486550 25mg $1210 Buy

Ethyl (2R,4S)-4-([1,1'-biphenyl]-4-ylmethyl)-2-methyl-4-(2,5-dioxopyrrolidin-1-yl)butanoate Chemical Properties,Uses,Production

Uses

Sacubitril Impurity 2 is an impurity of Sacubitril (S080895) which is an antihypertensive drug used in combination with valsartan.

Ethyl (2R,4S)-4-([1,1'-biphenyl]-4-ylmethyl)-2-methyl-4-(2,5-dioxopyrrolidin-1-yl)butanoate Preparation Products And Raw materials

Raw materials

Preparation Products

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Ethyl (2R,4S)-4-([1,1'-biphenyl]-4-ylmethyl)-2-methyl-4-(2,5-dioxopyrrolidin-1-yl)butanoate LCZ700 (2R,4S)-ethyl 5-([1,1'-biphenyl]-4-yl)-4-(2,5-dioxopyrrolidin-1-yl)-2-methylpentanoate LCZ696-9 LCZ696(valsartan + sacubitril) impurity 9 ethyl(2R,4S)-5-([1,1'-biphenyl]-4-yl)-4-(2,5-dioxopyrrolidin-1-yl)-2-methylpentanoate LCZ-696 Impurity 4 LCZ-696-006-RS LCZ-696-006-2R4S Sacubitril 2,5-Dioxopyrrolidine Valsartan Impurity 77 Sakubiter Impurity 2 1-Pyrrolidinebutanoic acid, γ-([1,1'-biphenyl]-4-ylmethyl)-α-methyl-2,5-dioxo-, ethyl ester, (αR,γS)- (2R,4S)-5-(Biphenyl-4-yl)-4-(2,5-dioxopyrrolidin-1-yl)-2-methylpentanoic acid ethyl ester SACUBITRIL SUCCINIMIDE Salcubatra calcium impurity P Valsartan Impurity 40(Sacubitril impurity 40) Shakubatura calcium impurity M LCZ-696 Impurity 550-06 1038924-97-8 LCZ696