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Salicylcurcumin

CAS No.
1236545-54-2
Chemical Name:
Salicylcurcumin
Synonyms
Salicylcurcumin;(1E,4Z,6E)-5-hydroxy-1,7-bis(2-hydroxyphenyl)hepta-1,4,6-trien-3-one;1,4,6-Heptatrien-3-one, 5-hydroxy-1,7-bis(2-hydroxyphenyl)-, (1E,4Z,6E)-
CBNumber:
CB63152737
Molecular Formula:
C19H16O4
Molecular Weight:
308.33
MDL Number:
MOL File:
1236545-54-2.mol
MSDS File:
SDS
Last updated:2023-05-21 10:59:17

Salicylcurcumin Properties

Boiling point 556.1±50.0 °C(Predicted)
Density 1.319±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMF: 30 mg/ml; DMSO: 20 mg/ml; Ethanol: 20 mg/ml
form A crystalline solid
pka 8.34±0.60(Predicted)

Salicylcurcumin price More Price(4)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 11878 Salicylcurcumin ≥95% 1236545-54-2 1mg $81 2024-03-01 Buy
Cayman Chemical 11878 Salicylcurcumin ≥95% 1236545-54-2 5mg $356 2024-03-01 Buy
Cayman Chemical 11878 Salicylcurcumin ≥95% 1236545-54-2 10mg $632 2024-03-01 Buy
AK Scientific 4083CS 1,7-Bis(2-hydroxyphenyl)-5-hydroxy-1,4,6-heptatriene-3-one 1236545-54-2 5mg $495 2021-12-16 Buy
Product number Packaging Price Buy
11878 1mg $81 Buy
11878 5mg $356 Buy
11878 10mg $632 Buy
4083CS 5mg $495 Buy

Salicylcurcumin Chemical Properties,Uses,Production

Description

Curcuminoids are natural and synthetic analogs of curcumin , a natural polyphenol with modulating effects in inflammation, cancer, and immunity.1 Salicylcurcumin is a synthetic curcuminoid which, like bisdemethoxycurcumin , lacks methoxy groups on both phenols. Furthermore, the hydroxyl groups on each phenol are positioned ortho, as in salicylates, rather than in the para position typical of curcuminoids. Salicylcurcumin has antioxidant and anticarcinogenic properties.2,3 Also, it increases the activity of quinone reductase in mouse hepatoma cells in a dose-dependent fashion, doubling activity at 0.3 μM salicylcurcumin.4,5

References

1. Grynkiewicz, G., and Slifirski, P. Curcumin and curcuminoids in quest for medicinal status Acta Biochim. Pol. 59(2),201-212(2012).
2. Manju, M., Sherin, T.G., Rajasekharan, K.N., et al. Curcumin analogue inhibits lipid peroxidation in a freshwater teleost, Anabas testudineus (Bloch)--an in vitro and in vivo study Fish Physiol. Biochem. 35(3),413-420(2009).
3. Anto, R.J., George, J., Babu, K.V., et al. Antimutagenic and anticarcinogenic activity of natural and synthetic curcuminoids Mutat. Res. 370(2),127-131(1996).
4. Dinkova-Kostova, A.T., and Talalay, P. Relation of structure of curcumin analogs to their potencies as inducers of Phase 2 detoxification enzymes Carcinogenesis 20(5),911-914(1999).
5. Magesh, S., Chen, Y., and Hu, L. Small molecule modulators of Keap1-Nrf2-ARE pathway as potential preventive and therapeutic agents Med. Res. Rev. 32(4),687-726(2012).

Salicylcurcumin Preparation Products And Raw materials

Raw materials

Preparation Products

Salicylcurcumin Suppliers

Global( 22)Suppliers
Supplier Tel Email Country ProdList Advantage
Career Henan Chemica Co
+86-0371-86658258 +8613203830695 laboratory@coreychem.com China 30250 58
Shanghai Hongye Biotechnology Co. Ltd 400-9205774 sales@glpbio.cn China 6870 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11289 58
MedBioPharmaceutical Technology Inc 021-69568360 18916172912 order@med-bio.cn China 8141 58
Nanjing Tengyi Biotechnology Co., Ltd 025-58851786 17714337195 sales@tybiochem.com China 5597 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 11975 58
Salicylcurcumin (1E,4Z,6E)-5-hydroxy-1,7-bis(2-hydroxyphenyl)hepta-1,4,6-trien-3-one 1,4,6-Heptatrien-3-one, 5-hydroxy-1,7-bis(2-hydroxyphenyl)-, (1E,4Z,6E)- 1236545-54-2