ChemicalBook >> CAS DataBase List >>4H-Quinolizine-3-carboxylicacid, 8-[(3S)-3-amino-1-pyrrolidinyl]-1-cyclopropyl-7-fluoro-9-methyl-4-oxo-,hydrochloride (1:1)
4H-Quinolizine-3-carboxylicacid, 8-[(3S)-3-amino-1-pyrrolidinyl]-1-cyclopropyl-7-fluoro-9-methyl-4-oxo-,hydrochloride (1:1)
- CAS No.
- 162763-53-3
- Chemical Name:
- 4H-Quinolizine-3-carboxylicacid, 8-[(3S)-3-amino-1-pyrrolidinyl]-1-cyclopropyl-7-fluoro-9-methyl-4-oxo-,hydrochloride (1:1)
- Synonyms
- A-86719.1;A-816719.1;A 816719.1;ABT-719 HCl;ABT-719 hydrochloride;ABT719 HCl,ABT 719 HCl;ABT-719;ABT 719;ABT719;A-86719.1;4H-Quinolizine-3-carboxylicacid, 8-[(3S)-3-amino-1-pyrrolidinyl]-1-cyclopropyl-7-fluoro-9-methyl-4-oxo-,hydrochloride (1:1)
- CBNumber:
- CB63196924
- Molecular Formula:
- C18H21ClFN3O3
- Molecular Weight:
- 381.83
- MDL Number:
- MOL File:
- 162763-53-3.mol
Last updated:2023-03-31 09:12:57
4H-Quinolizine-3-carboxylicacid, 8-[(3S)-3-amino-1-pyrrolidinyl]-1-cyclopropyl-7-fluoro-9-methyl-4-oxo-,hydrochloride (1:1) price
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
American Custom Chemicals Corporation | API0025298 | A-86719.1 95.00% | 162763-53-3 | 5MG | $504.2 | 2021-12-16 | Buy |
DC Chemicals | DC9261 | ABT-719HCl >98% | 162763-53-3 | 100mg | $550 | 2021-12-16 | Buy |
DC Chemicals | DC9261 | ABT-719HCl >98% | 162763-53-3 | 1g | $2100 | 2021-12-16 | Buy |
4H-Quinolizine-3-carboxylicacid, 8-[(3S)-3-amino-1-pyrrolidinyl]-1-cyclopropyl-7-fluoro-9-methyl-4-oxo-,hydrochloride (1:1) Chemical Properties,Uses,Production
Description
ABT-719 is a 2-pyridone antimicrobial with activity against enterococci, Escherichia coli, and Pseudomonas aeruginosa in experimental murine pyelonephritis. Therapeutic ED50s for ABT-719 against these infections were equal to or up to ten-fold lower than those for ciprofloxacin, used as a reference because of similarity in mode of action. Against E. faecalis, the therapeutic ED50s for ABT-719 were 4.5-13.6 mg/kg.day for sc administration and 6.8-8.9 mg/kg.day for oral administration. ABT-719 was more potent than ciprofloxacin and vancomycin against the E. faecalis strains, which showed ciprofloxacin and vancomycin resistance covering a range of MICs.
4H-Quinolizine-3-carboxylicacid, 8-[(3S)-3-amino-1-pyrrolidinyl]-1-cyclopropyl-7-fluoro-9-methyl-4-oxo-,hydrochloride (1:1) Preparation Products And Raw materials
Raw materials
Preparation Products
4H-Quinolizine-3-carboxylicacid, 8-[(3S)-3-amino-1-pyrrolidinyl]-1-cyclopropyl-7-fluoro-9-methyl-4-oxo-,hydrochloride (1:1) Suppliers
Global( 5)Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
TargetMol Chemicals Inc. | +1-781-999-5354 | support@targetmol.com | United States | 19973 | 58 |
ShenZhen Trendseen Biological Technology Co.,Ltd. | 13417589054 | trendseenbio@gmail.com | China | 11681 | 58 |
DC Chemicals | 021-58447131 13564518121 | sales@dcchemicals.com | China | 9412 | 58 |
Absin Bioscience Inc. | 021-38015121 15000105423 | wulan@absin.cn | China | 24734 | 58 |
TargetMol Chemicals Inc. | 4008200310 | marketing@tsbiochem.com | China | 23963 | 58 |
Supplier | Advantage |
---|---|
TargetMol Chemicals Inc. | 58 |
ShenZhen Trendseen Biological Technology Co.,Ltd. | 58 |
DC Chemicals | 58 |
Absin Bioscience Inc. | 58 |
TargetMol Chemicals Inc. | 58 |
4H-Quinolizine-3-carboxylicacid, 8-[(3S)-3-amino-1-pyrrolidinyl]-1-cyclopropyl-7-fluoro-9-methyl-4-oxo-,hydrochloride (1:1)
A-86719.1
ABT-719;ABT 719;ABT719;A-86719.1
ABT-719 HCl
A 816719.1
A-816719.1
ABT-719 hydrochloride
ABT719 HCl,ABT 719 HCl
162763-53-3
C18H20FN3O3ClH