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Triethylene glycol dimethyl ether

CAS No.
112-49-2
Chemical Name:
Triethylene glycol dimethyl ether
Synonyms
TRIGLYME;2,5,8,11-TETRAOXADODECANE;1,2-BIS(2-METHOXYETHOXY)ETHANE;DIMETHYLTRIGLYCOL;glyme4;Glyme-3;riglyme;ansulether161;dimethyltrigol;methyltriglyme
CBNumber:
CB6326946
Molecular Formula:
C8H18O4
Molecular Weight:
178.23
MDL Number:
MFCD00008504
MOL File:
112-49-2.mol
MSDS File:
SDS
Last updated:2024-10-25 16:21:11

Triethylene glycol dimethyl ether Properties

Melting point −45 °C(lit.)
Boiling point 216 °C(lit.)
Density 0.986 g/mL at 25 °C(lit.)
vapor density >4.7 (vs air)
vapor pressure 1.2 hPa (20 °C)
refractive index n20/D 1.423(lit.)
Flash point 231 °F
storage temp. Store below +30°C.
solubility >1000g/l soluble
form Liquid
color APHA: ≤20
explosive limit 0.7%(V)
Water Solubility Soluble
Sensitive Hygroscopic
Merck 14,9692
BRN 1700630
Dielectric constant 7.5
InChIKey YFNKIDBQEZZDLK-UHFFFAOYSA-N
LogP -0.52 at 20℃
CAS DataBase Reference 112-49-2(CAS DataBase Reference)
EWG's Food Scores 2
FDA UNII 32YXG88KK0
NIST Chemistry Reference 2,5,8,11-Tetraoxadodecane(112-49-2)
EPA Substance Registry System Triethylene glycol dimethyl ether (112-49-2)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictograms
GHS07,GHS08
Signal word  Danger
Hazard statements  H319-H360Df
Precautionary statements  P202-P264-P280-P305+P351+P338-P308+P313-P337+P313
Hazard Codes  T
Risk Statements  61-19-62
Safety Statements  53-45
WGK Germany  1
RTECS  XF0665000
3
Autoignition Temperature 375 °F
TSCA  Yes
HS Code  29094990
Toxicity LD50 orally in Rabbit: 5390 mg/kg
NFPA 704
1
1 0

Triethylene glycol dimethyl ether price More Price(19)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich T59803 Triethylene glycol dimethyl ether ReagentPlus , 99% 112-49-2 250g $77.7 2024-03-01 Buy
Sigma-Aldrich 8.08249 Triethylene glycol dimethyl ether (stabilised) for synthesis 112-49-2 250ML $48.8 2024-03-01 Buy
Sigma-Aldrich 05284 Triethylene glycol dimethyl ether analytical standard 112-49-2 50mg $86.2 2022-05-15 Buy
TCI Chemical B0496 Triethylene Glycol Dimethyl Ether (stabilized with BHT) >99.0%(GC) 112-49-2 25g $26 2024-03-01 Buy
TCI Chemical B0496 Triethylene Glycol Dimethyl Ether (stabilized with BHT) >99.0%(GC) 112-49-2 500g $68 2024-03-01 Buy
Product number Packaging Price Buy
T59803 250g $77.7 Buy
8.08249 250ML $48.8 Buy
05284 50mg $86.2 Buy
B0496 25g $26 Buy
B0496 500g $68 Buy

Triethylene glycol dimethyl ether Chemical Properties,Uses,Production

Chemical Properties

Water-white liquid; mild ether odor. D 0.9862 (20/20C), refr index 1.4233 (20C), flash p 232F (111C), bp 216.0C (760mmHg), 153.6C (100 mm Hg), fp ?46C. Completely soluble in water and hydrocarbons at 20C. May contain peroxides. Combustible.

Uses

Labelled Triglyme. It is used as a solvent.

Uses

Triethylene glycol dimethyl ether is used as a solvent for gases and coupling immiscible liquid. It is also used to prepare perfluoro-triethyleneglycoldimethylether.

Uses

Triethylene glycol dimethyl ether may be used as an analytical standard for the quantification of the analyte in water samples using in vitro bioassays and chemical screening technique.

Definition

ChEBI: A polyether that consists of dodecane in which the carbon atoms at positions 2, 5, 8 and 11 are replaced by oxygen atoms.

Application

Triethylene glycol dimethyl ether is a member of the glycol ether class of industrial solvents. These solvents are widely used to manufacture protective coatings such as lacquers, metal coatings, baking enamels, phenolic varnishes, epoxy resin coatings, and alkyl resins[1].

Reactivity Profile

TRIETHYLENE GLYCOL DIMETHYL ETHER forms explosive peroxides on prolonged exposure to air. Its decomposition products may be sensitive to shock. The bulk chemical is stable for 2 weeks at temperatures up to 140° F when protected from light. TRIETHYLENE GLYCOL DIMETHYL ETHER is incompatible with strong oxidizers. TRIETHYLENE GLYCOL DIMETHYL ETHER is also incompatible with strong acids. TRIETHYLENE GLYCOL DIMETHYL ETHER may react with peroxides, oxygen, nitric acid and sulfuric acid. .

Flammability and Explosibility

Non flammable

Toxicology

Triethylene glycol dimethyl ether (triEGdiME) is a widely used organic solvent. It is structurally related to several compounds that produce reproductive and developmental toxicity, including teratogenicity in laboratory animals. In the present studies, triEGdiME (0, 75, 125, 175, or 250 mg/kg/day) is administered by gavage in distilled water to timed-pregnant New Zealand white rabbits (15-25 dams/group) during major organogenesis [Gestational Days (gd) 6-19]. In the triEGdiME study, clinical signs of toxicity were minimal, and there was no increased maternal mortality. Maternal body weight and gravid uterine weight were significantly reduced at 250 mg/kg/day, whereas maternal weight gain during treatment was significant. They were depressed at doses of 175 mg/kg/day and above. Prenatal mortality was significantly increased at 250 mg triEGdiME/kg/day. TriEGdiME at doses of 175 and 250 mg/kg/day caused a significant increase in the incidence of malformed fetuses per litter. Malformations noted most frequently in fetuses of normal size included anonychia (missing toenails with no digital abnormalities), abnormally small spleen, and hydronephrosis[1].

Purification Methods

Reflux it with, and distil it from sodium hydride or LiAlH4. [Beilstein 1 IV 2401.]

Triethylene glycol dimethyl ether Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 285)Suppliers
Supplier Tel Email Country ProdList Advantage
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View Lastest Price from Triethylene glycol dimethyl ether manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Triethylene glycol dimethyl ether pictures 2024-11-25 Triethylene glycol dimethyl ether
112-49-2
US $5.00 / kg 1kg ≥99% 200mt/year Jinan Finer Chemical Co., Ltd
Triethylene glycol dimethyl ether pictures 2024-10-25 Triethylene glycol dimethyl ether
112-49-2
US $30.00-10.00 / KG 50KG 99% 500000kg Hebei Weibang Biotechnology Co., Ltd
  TRIETHYLENE GLYCOL DIMETHYL ETHER pictures 2024-10-11 TRIETHYLENE GLYCOL DIMETHYL ETHER
112-49-2
US $10.60 / KG 1KG 99% 5000kg Hebei Chuanghai Biotechnology Co,.LTD
1,2-BIS(METHOXYETHOXY)ETHANE TRIETHYLENE GLYCOL DIMETHYL ETHER TRIETHYLENE GLYCOL DIMETHYL ETHER, ABS., OVER MOL. SIEVE 2-(2-Methoxyethoxy)ethyl 2-methoxyethyl ether Triethylene glycol dimethyl ether, stabilized, 99% dimethyltrigol ansulether161 Dimethyl ether of triethylene glycol Ethane, 1,2-bis(2-methoxyethoxy)- ethane,1,2-bis(2-methoxyethoxy)- Glyme-3 glyme4 methyltriglyme triglyme (triethylene glycol dimethyl ether) Triethylene glycol dimethyl ether, stabilized, extra pure, 99% Tetraoxa dodecane Triethylene glycol diMethyl ether, 99%, extra pure, stabilized Triethylene glycol diMethyl ether, stabilized, 99% 1LT Triethylene glycol diMethyl ether, stabilized, 99% 250ML Triethylene Glycol DiMethyl Ether(1,2-Di(2-Methoxy ethoxy)ethane) 1,2-Bis(2-methoxyethoxy)ethan Triethylene glycol dimethyl ether, 99%, stabilized 1,1'-(Ethylenebisoxy)bis(2-methoxyethane) 1,8-Dimethoxy-3,6-dioxaoctane 1,2-bis(2-methoxyethoxy)ethane TEGDME triethylene glycol dimethyl ether triglyme 1,2-Bis(2-methoxyethoxy)ethane, Dimethyltriglycol, Triglyme 1-Methoxy-2-[2-(2-methoxy-ethoxy)-ethoxy]-ethane Triethylene glycol d (CH3O(CH2)2OCH2)2 Ansul Ether 161 Triethylene Glycol DiMethyl Ether (stabilized with BHT) 1,2-Bis(2-methoxyethoxy)ethane 2,5,8,11-Tetraoxadodecane Triglyme TRIETHYLENE GLYCOL DIMETHYL ETHER FOR SY 1,2-Bis(2-Methoxyethoxy) Ethane, Reagent Triethylene glycol diMethyl et Triethylene glycol dimethyl ether ReagentPlus(R), 99% Triethylene glycol dimethyl ether Vetec(TM) reagent grade, 98% Ttiethylene Glycol Dimethyl Ether acetic acid 3-acetyloxybutyl ester Triethylene Glycol Dimethyl Ether (stabilized with BHT)> Triethylene glycol dimethyl ether,>99% riglyme Hot Selling Factory Supply High Quality TRIETHYLENE GLYCOL DIMETHYL ETHER CAS 112-49-2 2,5,8,11-TETRAOXADODECANE 1,2-BIS(2-METHOXYETHOXY)ETHANE TRIGLYME DIMETHYLTRIGLYCOL Triethylene glycol dimethyl ether in methanol 112-49-2 C8H12D6O4 CH3OCH2CH2O3CH3 Polyalcohol Ethers, Esters (Plasticizer) Plasticizer Building Blocks Ethers Organic Building Blocks Oxygen Compounds Building Blocks