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Sitagliptin Impurity 10

Sitagliptin Impurity 10 structure

CAS No.: 1253056-01-7

Chemical Name:: Sitagliptin Impurity 10

Synonyms: Sitagliptin-8;Sitagliptin Impurity;3-Hydroxy Sitagliptin;Sitagliptin Impurity 09;Sitagliptin phosphate impurity 6;Sitagliptin Hydroxy Amide Impurity;1-[5,6-Dihydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazin-7(8H)-yl]-3-hydroxy-4-(2,4,5-trifluo;1-[5,6-Dihydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-α]pyrazin-7(8H)-yl]-3-hydroxy-4-(2,4,5-trifluorophenyl)-1-butanone;1-Butanone, 1-[5,6-dihydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazin-7(8H)-yl]-3-hydroxy-4-(2,4,5-trifluorophenyl)-;3-hydroxy-1-(3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo [4,3-a]pyrazin-7(8H)-yl)-4-(2,4,5-trifluorophenyl)butan-1-one

CBNumber:: CB63360062

Molecular Formula:: C16H14F6N4O2

Molecular Weight:: 408.3

MDL Number:: MFCD30747641

MOL File:: 1253056-01-7.mol

Last updated:2023-05-15 10:44:02

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Sitagliptin Impurity 10 Properties

Boiling point	542.2±60.0 °C(Predicted)
Density	1.61±0.1 g/cm3(Predicted)
solubility	Chloroform (Slightly), Methanol (Slightly)
form	Solid
pka	13.69±0.20(Predicted)
color	White to Off-White

Sitagliptin Impurity 10 Chemical Properties,Uses,Production

Uses

1-[5,6-Dihydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazin-7(8H)-yl]-3-hydroxy-4-(2,4,5-trifluorophenyl)-1-butanone is an intermediate in the synthesis of 3-Desamino-2,3-dehydro Sitagliptin (D281985), which is an impurity of Sitagliptin (S491000); a trizolopyrazine dipeptidyl peptidase IV inhibitor. Sitagliptin has recently been approved for the therapy of type II diabetes.

Sitagliptin Impurity 10 Preparation Products And Raw materials

Raw materials

Preparation Products

Sitagliptin Impurity 10 Suppliers

Global( 44)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Standardpharm Co. Ltd.	86-714-3992388	overseasales1@yongstandards.com	United States	14332	58
Hangzhou Huarong Pharm Co., Ltd.	571-86758373 +8613588754946	sales@huarongpharm.com	CHINA	3148	58
sgtlifesciences pvt ltd	+8617013299288	dj@sgtlifesciences.com	China	12373	58
China National Standard Pharmaceutical Corporation Limited	+8615391658522	overseasales@yongstandards.com	China	11922	58
Moxin Chemicals	+8617320513646	mike@molcoo.com	China	9457	58
Shanghai Payne Pharmaceutical Technology Co.Ltd	021-58123769 18678586262	info@paynepharm.com	China	1354	58
QUALITY CONTROL SOLUTIONS LTD.	0755-66853366; 13670046396	ORDERS@QCSRM.COM	China	24342	58
Daicel Chiral Technologies (China)CO.,LTD	021-50460086-9 15921403865	han_yajun@dctc.daicel.com	China	7195	65
BOC Sciences	1-631-485-4226; 16314854226	info@bocsci.com	United States	14055	65
Beijing Comparison Pharmaceutical Technology Co., Ltd	010-010-52878169 15801002657	sales@bjcomparison.com	China	5004	58

Supplier	Advantage
Standardpharm Co. Ltd.	58
Hangzhou Huarong Pharm Co., Ltd.	58
sgtlifesciences pvt ltd	58
China National Standard Pharmaceutical Corporation Limited	58
Moxin Chemicals	58
Shanghai Payne Pharmaceutical Technology Co.Ltd	58
QUALITY CONTROL SOLUTIONS LTD.	58
Daicel Chiral Technologies (China)CO.,LTD	65
BOC Sciences	65
Beijing Comparison Pharmaceutical Technology Co., Ltd	58

1253056-01-7(Sitagliptin Impurity 10)Related Search:

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1of4

Sitagliptin-8 Sitagliptin Hydroxy Amide Impurity Sitagliptin impurity 41/Sitagliptin Hydroxy Amide Impurity/3-hydroxy-1-(3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo [4,3-a]pyrazin-7(8H)-yl)-4-(2,4,5-trifluorophenyl)butan-1-one 3-hydroxy-1-(3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo [4,3-a]pyrazin-7(8H)-yl)-4-(2,4,5-trifluorophenyl)butan-1-one 1-Butanone, 1-[5,6-dihydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazin-7(8H)-yl]-3-hydroxy-4-(2,4,5-trifluorophenyl)- (R/S)-3-hydroxy-1-(3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)-4-(2,4,5-trifluorophenyl)butan-1-one 1-[5,6-Dihydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazin-7(8H)-yl]-3-hydroxy-4-(2,4,5-trifluo Sitagliptin phosphate impurity 6 Sitagliptin Impurity 09 3-hydroxy-1-(3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)-4-(2,4,5-trifluorophenyl)butan-1-one? (Sitagliptin Impurity） 3-Hydroxy Sitagliptin 1-[5,6-Dihydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-α]pyrazin-7(8H)-yl]-3-hydroxy-4-(2,4,5-trifluorophenyl)-1-butanone Sitagliptin Impurity 1253056-01-7