ChemicalBook >> CAS DataBase List >>(-)-3,4-Dihydroxynorephedrine
(-)-3,4-Dihydroxynorephedrine
- CAS No.
- 829-74-3
- Chemical Name:
- (-)-3,4-Dihydroxynorephedrine
- Synonyms
- BA 2818;Nordefri;CORBADRINE;l-Cobefrin;Neo-cobefrin;LEVONORDEFRIN;Isoadrenaline;D-(-)-Cobefrin;Levonordefrin Base;Dioxynorepinephrine
- CBNumber:
- CB6344074
- Molecular Formula:
- C9H13NO3
- Molecular Weight:
- 183.2
- MDL Number:
- MFCD00134415
- MOL File:
- 829-74-3.mol
Last updated:2023-06-08 09:02:54
Melting point | 212-215°C dec. |
---|---|
alpha | D25 -31.0° (c = 0.5 in 0.01N HCl) |
Boiling point | 431.6±40.0 °C(Predicted) |
Density | 1.328±0.06 g/cm3(Predicted) |
storage temp. | −20°C |
solubility | DMSO: soluble5mg/mL, clear (warmed) |
pka | 9.59±0.10(Predicted) |
form | powder |
color | white to light brown |
Merck | 13,6725 |
EWG's Food Scores | 1 |
FDA UNII | V008L6478D |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS07 |
|||||||||
---|---|---|---|---|---|---|---|---|---|---|
Signal word | Warning | |||||||||
Hazard statements | H302+H312+H332-H315-H319-H335 | |||||||||
Precautionary statements | P261-P280-P301+P312+P330-P305+P351+P338 | |||||||||
Hazard Codes | Xn | |||||||||
Risk Statements | 20/21/22-36/37/38 | |||||||||
Safety Statements | 26-36 | |||||||||
RIDADR | UN 2811 6.1 / PGII | |||||||||
WGK Germany | 3 | |||||||||
HS Code | 2922504500 | |||||||||
Toxicity | LD50 in mice (mg/kg): 12.6 i.v. (Luduena) | |||||||||
NFPA 704 |
|
(-)-3,4-Dihydroxynorephedrine Chemical Properties,Uses,Production
Chemical Properties
White Powder
Uses
A vasoconstrictor which also increases the potency and duration of anesthesia produced by local anesthetics
Uses
Vasoconstrictor;Adrenergic receptor agonist
Definition
ChEBI: Alpha-methylnoradrenaline is a catecholamine in which the 2-aminoethyl group is substituted with a hydroxy group at C-1 and a methyl group at C-2, with configurations 1R,2S. A metabolite of alpha-methyl-L-dopa, it is an alpha2-adrenergic agonist and acts as a topical nasal decongestant and vasoconstrictor, most often used in dentistry. It has a role as an alpha-adrenergic agonist, a vasoconstrictor agent and a nasal decongestant.
brand name
Neo-Cobefrin (Cook-Waite).
(-)-3,4-Dihydroxynorephedrine Preparation Products And Raw materials
Raw materials
Preparation Products
829-74-3((-)-3,4-Dihydroxynorephedrine)Related Search:
4-[2-AMINO-1-HYDROXYPROPYL]-1,2-BENZENEDIOL
(-)3,4-DIHYDROXYNOREPHEDRINE
(-)-3,4-DIHYDROXYNOREPHREDRINE
CORBADRINE
LEVONORDEFRIN
Dihydroxyphenylpropanolamine
Dioxynorepinephrine
Isoadrenaline
Nordefri
Corbadrine, Levonordefrin, l-Norephedrine
(-)-3,4-DIHYDROXYNOREPHEDRINE, TECH., 90 %
(-)-3,4-DIHYDROXYNOREPHEDRINE*APPROX. 90 %
Corbadrine, Levonordefrin,
(-)-α-methylnorepinephrine
α-(1-Aminoethyl)-3,4-dihydroxybenzyl alcohol, (-)-α-Methylnorepinephrine, 4-(2-Amino-1-hydroxypropyl)-1,2-benzenediol, L-4-(2-Amino-1-hydroxypropyl)-1,2-benzenediol, Levonordefrin
(-)-4-[(1R,2S)-2-Amino-1-hydroxypropyl]-1,2-benzenediol
(1R,2S)-2-Amino-1-(3,4-dihydroxyphenyl)-1-propanol
(-)-3,4-Dihydroxynorephedrine
4-(2-Amino-1-hydroxypropyl)benzene-1,2-diol
Levonordefrin (200 mg)
BA 2818
D-(-)-Cobefrin
l-Cobefrin
L-α-Methylnoradrenaline
Neo-cobefrin
α-(1-Aminoethyl)-3,4-dihydroxybenzyl alcohol, (-)-α-Methylnorepinephrine, 4-(2-Amino-1-hydroxypropyl)-1,2-benzenediol, L-4-(2-Amino-1-hydroxypropyl)-1,2-benzenediol
1,2-Benzenediol, 4-(2-amino-1-hydroxypropyl)-
1,2-Benzenediol, 4-(2-amino-1-hydroxypropyl)- (9CI)
Levonordefrin Base
3,4-Dihydrophenyl-1-amino-2-propanol-1
BENZYL ALCOHOL, alpha-(1-AMINOETHYL)-3,4-DIHYDROXY-
4-(2-amino-1-hydroxy-propyl)pyrocatechol
4-dihydroxy Norephedrine
LEVONORDEFRIN;CORBADRINE;(–)-Α-METHYL NORADRENALINE;(–)-3;4-DIHYDROXY NOREPHEDRINE
1,2-Benzenediol, 4-[(1R,2S)-2-amino-1-hydroxypropyl]-
Levonordefrin (1362500)
(–)-3,4-dihydroxy Norephedrine
(–)-α-methyl Noradrenaline
829-74-3
HO2C6H3CHOHCHCH3NH2
DID - DIN
Analytical Chromatography Product Catalog
Alphabetic
Analytical Standards
Amines
Aromatics
Intermediates & Fine Chemicals
Pharmaceuticals