Estradiol benzoate
- CAS No.
- 50-50-0
- Chemical Name:
- Estradiol benzoate
- Synonyms
- ODB;MEE;Oestradiol benzoate;EBZ;folone;17β-Estradiol benzoate;(17beta)-Estra-1,3,5(10)-triene-3,17-diol 3-benzoate;ESTON-B;diogynb;Graafina
- CBNumber:
- CB9131644
- Molecular Formula:
- C25H28O3
- Molecular Weight:
- 376.5
- MDL Number:
- MFCD00003692
- MOL File:
- 50-50-0.mol
- MSDS File:
- SDS
Melting point | 191-198 °C(lit.) |
---|---|
alpha | D25 +58 to +63° (c = 2 in dioxane) |
Boiling point | 465.03°C (rough estimate) |
Density | 1.0493 (rough estimate) |
refractive index | 1.5460 (estimate) |
storage temp. | 2-8°C |
solubility | Practically insoluble in water, freely soluble in methylene chloride, sparingly soluble in acetone, slightly soluble in methanol. |
form | Solid |
pka | 15.06±0.40(Predicted) |
color | White |
Water Solubility | 0.4mg/L(25 ºC) |
Merck | 3703 |
BRN | 3107526 |
CAS DataBase Reference | 50-50-0(CAS DataBase Reference) |
EWG's Food Scores | 1 |
FDA UNII | 1S4CJB5ZGN |
NIST Chemistry Reference | Estradiol benzoate(50-50-0) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() GHS08 |
---|---|
Signal word | Danger |
Hazard statements | H351-H360FD |
Precautionary statements | P201-P202-P280-P308+P313-P405-P501 |
Hazard Codes | T |
Risk Statements | 60-61-40 |
Safety Statements | 53-22-36/37/39-45 |
WGK Germany | 3 |
RTECS | KG4050000 |
F | 8 |
HS Code | 29372319 |
Estradiol benzoate price More Price(27)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | E8515 | β-Estradiol 3-benzoate ≥97% | 50-50-0 | 1g | $111 | 2024-03-01 | Buy |
Sigma-Aldrich | PHR2858 | Estradiol Benzoate certified reference material, pharmaceutical secondary standard | 50-50-0 | 500MG | $286 | 2024-03-01 | Buy |
Sigma-Aldrich | BP396 | Estradiol benzoate British Pharmacopoeia (BP) Reference Standard | 50-50-0 | 50MG | $220 | 2024-03-01 | Buy |
Sigma-Aldrich | 1251000 | Estradiol benzoate United States Pharmacopeia (USP) Reference Standard | 50-50-0 | 250mg | $436 | 2024-03-01 | Buy |
Cayman Chemical | 10006487 | Estradiol Benzoate ≥98% | 50-50-0 | 500mg | $32 | 2024-03-01 | Buy |
Estradiol benzoate Chemical Properties,Uses,Production
Chemical Properties
White solid
Uses
antiacne, antineoplastic
Uses
Estradiol is the major estrogen secreted by the premenopausal ovary. Estradiol benzoate is an estradiol analog which contains a benzyl ester at the C-3 position. Estradiol benzoate is useful in the treatment of lesions produced by diminution of bodily production of estrogens.
Definition
ChEBI: A benzoate ester resulting from the formal condensation of benzoic acid with the phenolic hydroxy group of 17beta-estradiol.
Clinical Use
Estradiol is a semisynthetic estrogen compound. Its effects will mimic that of estrogen in animals. The most common use in small animals has been to terminate pregnancy.
Estradiol benzoate also has been used to terminate pregnancy (5-10 mg/kg divided into two or three SQ injections). Estradiol cypionate formulation had high efficacy (95%), but it had serious adverse effects and is not recommended. Estradiol cypionate is longer acting and more potent than other estrogen formulations. Estradiol valerate injection (20 mg/mL) is also available for human medicine to treat hypoestrogenism.
Safety Profile
Confirmed carcinogen with experimental carcinogenic, tumorigenic, and teratogenic data. Human reproductive effects by intramuscular route: menstrual cycle changes and disorders. Experimental reproductive effects. Mutation data reported. A steroid. When heated to decomposition it emits acrid smoke and irritating fumes. See also ESTRADIOL.
Estradiol benzoate Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Hebei Bonster Technology Co.,Limited | +8613315996897 | bsterltd.wendy@gmail.com | China | 796 | 58 |
Shenzhen Monkono Technology Co.,Ltd | +86-17063441314 | sansbiotech@outlook.com | China | 677 | 58 |
Shaanxi Dideu Medichem Co. Ltd | +86-29-81148696 +86-15536356810 | 1022@dideu.com | China | 3320 | 58 |
Hebei Yanxi Chemical Co., Ltd. | +86-17531190177; +8617531190177 | peter@yan-xi.com | China | 5873 | 58 |
Sinoway Industrial co., ltd. | 0592-5800732; +8613806035118 | xie@china-sinoway.com | China | 990 | 58 |
Hong Kong Excellence Biotechnology Co., Ltd. | ada@sh-teruiop.com | China | 882 | 58 | |
Wuhan Haorong Biotechnology Co.,ltd | +86-18565342920; +8618565342920 | sales@chembj.net | China | 289 | 58 |
Nantong Guangyuan Chemicl Co,Ltd | +undefined17712220823 | admin@guyunchem.com | China | 616 | 58 |
Sigma Audley | +86-18336680971 +86-18126314766 | nova@sh-teruiop.com | China | 491 | 58 |
Hebei Kangcang new material Technology Co., LTD | +8615713292910 | Nancy@kangcang.com.cn | China | 341 | 58 |
View Lastest Price from Estradiol benzoate manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
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2024-08-22 | estradiol benzoate
50-50-0
|
US $0.00-0.00 / Kg/Bag | 0.10000000149011612Kg/Bag | USP, GMP | 2tons | Sinoway Industrial co., ltd. | |
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2024-08-22 | Estradiol benzoate
50-50-0
|
US $0.00 / g/Bag | 100g | 97.0~103.0%; USP43 | 800kg/month | WUHAN FORTUNA CHEMICAL CO., LTD | |
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2024-08-15 | Estradiol benzoate
50-50-0
|
US $40.00-40.00 / kg | 1kg | 0.99 | 10 tons | Hebei Yanxi Chemical Co., Ltd. |
-
- estradiol benzoate
50-50-0
- US $0.00-0.00 / Kg/Bag
- USP, GMP
- Sinoway Industrial co., ltd.
-
- Estradiol benzoate
50-50-0
- US $0.00 / g/Bag
- 97.0~103.0%; USP43
- WUHAN FORTUNA CHEMICAL CO., LTD
-
- Estradiol benzoate
50-50-0
- US $40.00-40.00 / kg
- 0.99
- Hebei Yanxi Chemical Co., Ltd.