ChemicalBook >> CAS DataBase List >>(5-METHOXY-1H-INDOL-2-YL)PHENYLMETHANONE
(5-METHOXY-1H-INDOL-2-YL)PHENYLMETHANONE
- CAS No.
- 74588-78-6
- Chemical Name:
- (5-METHOXY-1H-INDOL-2-YL)PHENYLMETHANONE
- Synonyms
- D-6413;CS-888;D-64131;D 64131; D64131;D-64131(sc-203908);(5-METHOXY-1H-INDOL-2-YL)PHENYLMETHANONE;Methanone,(5-methoxy-1H-indol-2-yl)phenyl-;tubulin-inhibitory,D64131,Inhibitor,D-64131,G2/M,antiproliferative,inhibit,Microtubule/Tubulin,phase,carcinoma,antimitotic,activity,cytotoxicity,D 64131,astrocytoma
- CBNumber:
- CB6390031
- Molecular Formula:
- C16H13NO2
- Molecular Weight:
- 251.28
- MDL Number:
- MFCD04039791
- MOL File:
- 74588-78-6.mol
- MSDS File:
- SDS
Last updated:2024-11-19 20:33:22
| Melting point | 162 °C |
|---|---|
| Boiling point | 455.2±25.0 °C(Predicted) |
| Density | 1.231±0.06 g/cm3(Predicted) |
| storage temp. | Sealed in dry,Store in freezer, under -20°C |
| solubility | Soluble in DMSO |
| form | Crystalline solid |
| pka | 14.81±0.30(Predicted) |
| color | Light yellow to yellow |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319 |
| Precautionary statements | P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313 |
(5-METHOXY-1H-INDOL-2-YL)PHENYLMETHANONE price More Price(27)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Alfa Aesar | J65995 | D-64131 | 74588-78-6 | 10mg | $154 | 2021-12-16 | Buy |
| Cayman Chemical | 22944 | D-64131 ≥98% | 74588-78-6 | 5mg | $97 | 2024-03-01 | Buy |
| Cayman Chemical | 22944 | D-64131 ≥98% | 74588-78-6 | 10mg | $175 | 2024-03-01 | Buy |
| Cayman Chemical | 22944 | D-64131 ≥98% | 74588-78-6 | 25mg | $385 | 2024-03-01 | Buy |
| Cayman Chemical | 22944 | D-64131 ≥98% | 74588-78-6 | 50mg | $577 | 2024-03-01 | Buy |
(5-METHOXY-1H-INDOL-2-YL)PHENYLMETHANONE Chemical Properties,Uses,Production
Uses
Novel inhibitor of tubulin polymerization
Definition
ChEBI: (5-methoxy-1H-indol-2-yl)-phenylmethanone is a N-acylindole.
Biological Activity
Novel inhibitor of tubulin polymerization; cytotoxic and inhibits tumor cell proliferation in vitro (IC 50 = 74 nM). Prevents growth of tumor models in mice following oral administration in vivo .
References
1. beckers t, reissmann t, schmidt m et al. 2-aroylindoles, a novel class of potent, orally active small molecule tubulin inhibitors. cancer res. 2002 jun 1;62(11):3113-9.
(5-METHOXY-1H-INDOL-2-YL)PHENYLMETHANONE Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 73)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32957 | 60 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32161 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 +8613203830695 | laboratory@coreychem.com | China | 30239 | 58 |
| Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471 | sales@sarms4muscle.com | China | 10473 | 58 |
| InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6391 | 58 |
| ShenZhen Trendseen Biological Technology Co.,Ltd. | 13417589054 | trendseenbio@gmail.com | China | 11681 | 58 |
| Aladdin Scientific | +1-+1(833)-552-7181 | sales@aladdinsci.com | United States | 57505 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131957 | 58 |
| Shanghai Boyle Chemical Co., Ltd. | sales@boylechem.com | China | 2922 | 55 | |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 821-50328103-801 18930552037 | 3bsc@sina.com | China | 15839 | 69 |
View Lastest Price from (5-METHOXY-1H-INDOL-2-YL)PHENYLMETHANONE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-11-19 | D-64131
74588-78-6
|
US $29.00-95.00 / mg | 99.67% | 10g | TargetMol Chemicals Inc. | ||
 |
2024-10-22 | (5-METHOXY-1H-INDOL-2-YL)PHENYLMETHANONE
74588-78-6
|
US $1.00 / g | 1g | 85.0-99.8% | 20tons | Career Henan Chemica Co |
-
- D-64131
74588-78-6
- US $29.00-95.00 / mg
- 99.67%
- TargetMol Chemicals Inc.
-
- (5-METHOXY-1H-INDOL-2-YL)PHENYLMETHANONE
74588-78-6
- US $1.00 / g
- 85.0-99.8%
- Career Henan Chemica Co
74588-78-6((5-METHOXY-1H-INDOL-2-YL)PHENYLMETHANONE)Related Search:
D-64131
(5-METHOXY-1H-INDOL-2-YL)PHENYLMETHANONE
D-6413
D-64131(sc-203908)
CS-888
D 64131; D64131
Methanone,(5-methoxy-1H-indol-2-yl)phenyl-
tubulin-inhibitory,D64131,Inhibitor,D-64131,G2/M,antiproliferative,inhibit,Microtubule/Tubulin,phase,carcinoma,antimitotic,activity,cytotoxicity,D 64131,astrocytoma
74588-78-6
Inhibitors
Caspases/Apoptosis