ETHYLTHIOUREA
- CAS No.
- 625-53-6
- Chemical Name:
- ETHYLTHIOUREA
- Synonyms
- N-ETHYLTHIOUREA;Nsc62921;Ent 61326;ETHYLTHIOUREA;1-ETHYLTHIOUREA;ethyl-2-thiourea;Thiourea, ethyl-;Ethylthiourea,99%;1-ETHYL-2-THIOUREA;1-ethyl-2-thio-ure
- CBNumber:
- CB6416447
- Molecular Formula:
- C3H8N2S
- Molecular Weight:
- 104.17
- MDL Number:
- MFCD00004939
- MOL File:
- 625-53-6.mol
- MSDS File:
- SDS
Melting point | 108-110 °C(lit.) |
---|---|
Boiling point | 132 °C |
Density | 1.055 (estimate) |
refractive index | 1.5500 (estimate) |
storage temp. | Store at RT |
solubility | methanol: soluble25mg/mL, clear, colorless |
form | Solid |
pka | 14.97±0.29(Predicted) |
color | White to Off-White |
Water Solubility | Soluble in water (24g/L). |
BRN | 1699551 |
InChIKey | GMEHFXXZSWDEDB-UHFFFAOYSA-N |
CAS DataBase Reference | 625-53-6(CAS DataBase Reference) |
EWG's Food Scores | 1 |
FDA UNII | U54OR2E97E |
EPA Substance Registry System | Ethylthiourea (625-53-6) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS06 |
|||||||||
---|---|---|---|---|---|---|---|---|---|---|
Signal word | Danger | |||||||||
Hazard statements | H301 | |||||||||
Precautionary statements | P301+P310+P330 | |||||||||
Hazard Codes | T | |||||||||
Risk Statements | 25 | |||||||||
Safety Statements | 36/37/39-45 | |||||||||
RIDADR | UN 2811 6.1/PG 3 | |||||||||
WGK Germany | 3 | |||||||||
RTECS | YT3700000 | |||||||||
TSCA | Yes | |||||||||
HazardClass | 6.1 | |||||||||
PackingGroup | III | |||||||||
Hazardous Substances Data | 625-53-6(Hazardous Substances Data) | |||||||||
Toxicity | mouse,LDLo,oral,500mg/kg (500mg/kg),Teratology, The International Journal of Abnormal Development. Vol. 23, Pg. 335, 1981. | |||||||||
NFPA 704 |
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ETHYLTHIOUREA price More Price(11)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | 252530 | N-Ethylthiourea 99% | 625-53-6 | 10g | $208 | 2024-03-01 | Buy |
Alfa Aesar | B24761 | N-Ethylthiourea, 99% | 625-53-6 | 50g | $253 | 2021-12-16 | Buy |
Alfa Aesar | B24761 | N-Ethylthiourea, 99% | 625-53-6 | 10g | $71.9 | 2021-12-16 | Buy |
Alfa Aesar | B24761 | N-Ethylthiourea, 99% | 625-53-6 | 250g | $1230 | 2021-12-16 | Buy |
TRC | E926975 | Ethylthiourea | 625-53-6 | 10g | $110 | 2021-12-16 | Buy |
ETHYLTHIOUREA Chemical Properties,Uses,Production
Uses
N-Ethylthiourea was used in the preparation of Re (III) complexes, which are precursors for the new rhenium complexes, potentially useful in nuclear medicine. It was also used in two-step protocol for the first chemoselective cleavage of 2-hydroxy acid amides
Definition
ChEBI: N-ethylthiourea is a member of the class of thioureas that is thiourea in which one of the hydrogens is replaced by an ethyl group. It is functionally related to a thiourea.
General Description
N-Ethylthiourea forms adduct with silver halides and their single crystal X-ray structural and spectroscopic characterizations are described.
Biological Activity
Potent, selective and reversible inhibitor of isoform II NO synthase (IC 50 = 13 nM; approximately 20- and 30-fold selective over isoforms I and III respectively).
Safety Profile
Poison by ingestion. SYN: 1-ETHYLTHIOUREA Experimental teratogenic effects. Mutation data reported. When heated to decomposition it emits toxic fumes of Sox and NOx.
Purification Methods
Crystallise the thiourea from EtOH, MeOH or ether. [Beilstein 4 IV 374.]
ETHYLTHIOUREA Preparation Products And Raw materials
Supplier | Tel | Country | ProdList | Advantage | |
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CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49374 | 58 |
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