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4'-CHLORODIAZEPAM

4'-CHLORODIAZEPAM structure

CAS No.: 14439-61-3

Chemical Name:: 4'-CHLORODIAZEPAM

Synonyms: RO 5-4864;Aids080743;Aids-080743;chlorodiazepam;4'-CHLORODIAZEPAM;4'-Chlorodiazepam;RO-54864, 4'-chlorodiazepam;4'-Chlorodiazepam >=98% (TLC);TSPO Agonist, Ro5-4864 - CAS 14439-61-3 - Calbiochem;7-chloro-5(4-chlorophe)1,3-dihydro-1-me-1,4-benzodiaz.-2-on

CBNumber:: CB6430850

Molecular Formula:: C16H12Cl2N2O

Molecular Weight:: 319.19

MDL Number:: MFCD00043406

MOL File:: 14439-61-3.mol

MSDS File:: SDS

Last updated:2024-07-02 08:55:14

4'-CHLORODIAZEPAM Properties

Melting point	160-163 °C
Boiling point	517.1±50.0 °C(Predicted)
Density	1.35±0.1 g/cm3(Predicted)
storage temp.	+2C to +8C
solubility	ethanol: 17 mg/mL
form	Off-white powder
pka	3.08±0.10(Predicted)
color	White to light yellow
BRN	685202
FDA UNII	2QW0IK1742

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302
Precautionary statements	P264-P270-P301+P312-P501
Hazard Codes	Xn
Risk Statements	22
Safety Statements	22-24/25
RIDADR	2811
WGK Germany	3
RTECS	DF0500000
F	10
HazardClass	6.1(b)
PackingGroup	III

4'-CHLORODIAZEPAM Chemical Properties,Uses,Production

Uses

4′-Chlorodiazepam has been used as a translocator protein ligand in mitochondrial functional studies. It has also been used to investigate its protective effects on glucose deprived T98G astrocyte cell lines.

Biochem/physiol Actions

4′-Chlorodiazepam (Ro5-4864) is a potent selective ligand for the mitochondrial translocator protein 18kDa (TSPO), formerly known as the peripheral benzodiazepine receptor (PBR). Ro5-4864 does not bind to GABA(A) receptors and lacks typical benzodiazepine effects, but has been found to be neuroprotective in several studies.

4'-CHLORODIAZEPAM Preparation Products And Raw materials

Raw materials

Preparation Products

14439-61-3(4'-CHLORODIAZEPAM)Related Search:

Diazapam Nordazepam N-ME-GLY-NME2 BENZHYDRYLIDENE METHYLAMINE 4'-CHLORODIAZEPAM [N-METHYL-3H]

Benzophenone imine 4'-CHLORODIAZEPAM CHEMBRDG-BB 5668895 1-METHYL-5-PHENYL-1,3-DIHYDRO-BENZO[E][1,4]DIAZEPIN-2-ONE MEDAZEPAM

4-CHLORO-O-TOLUIDINE HYDROCHLORIDE 4-CHLORO-N,N-DIMETHYLANILINE 1,3-Dihydro-5-phenyl-1,4-benzodiazepin-2-one 4-CHLORO-2-METHYLACETANILIDE 4-CHLORO-N-METHYLFORMANILIDE

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7-Chloro-1,3-dihydro-1-methyl-5-(4-chlorophenyl)-2H-1,4-benzodiazepin-2-one 2H-1,4-Benzodiazepin-2-one, 7-chloro-5-(4-chlorophenyl)-1,3-dihydro-1-methyl- Aids080743 Aids-080743 7-chloro-1,3-dihydro-1-methyl-5-(p-chlorophenyl)-2h-1,4-benzodiazepin-2-one 7-chloro-5-(4-chlorophenyl)-1,3-dihydro-1-methyl-2h-4-benzodiazepin-2-one 7-chloro-5-(p-chlorophenyl)-1,3-dihydro-1-methyl-2h-4-benzodiazepin-2-one chlorodiazepam 7-CHLORO-5-(4-CHLOROPHENYL)-1,3-DIHYDRO-1-METHYL-2H-1,4-BENZODIAZEPIN-2-ONE 7-CHLORO-5-[4'-CHLOROPHENYL]-1,3-DIHYDRO-1-METHYL-2H-1,4-BENZODIAZEPIN-2-ONE 4'-CHLORODIAZEPAM RO 5-4864 7-chloro-5(4-chlorophe)1,3-dihydro-1-me-1,4-benzodiaz.-2-on Ro5-4864, 7-Chloro-5-(4-chlorophenyl)-1,3-dihydro-1-methyl-2H-1,4-benzodiazepin-2-one 1-Methyl-5-(4-chlorophenyl)-7-chloro-1H-1,4-benzodiazepine-2(3H)-one 1-Methyl-5-(p-chlorophenyl)-7-chloro-1,3-dihydro-2H-1,4-benzodiazepine-2-one 1-Methyl-7-chloro-5-(4-chlorophenyl)-1H-1,4-benzodiazepine-2(3H)-one TSPO Agonist, Ro5-4864 - CAS 14439-61-3 - Calbiochem 4'-Chlorodiazepam >=98% (TLC) RO-54864, 4'-chlorodiazepam 4'-Chlorodiazepam 14439-61-3