4-Chloro-1-(2-methylpropyl)-1H-imidazo[4,5-c]quinoline
- CAS No.
- 99010-64-7
- Chemical Name:
- 4-Chloro-1-(2-methylpropyl)-1H-imidazo[4,5-c]quinoline
- Synonyms
- cas 99010-64-7;Imiquimod USP RC C;Imiquimod Impurity-C;DesaMino ChloroiMiquiMod;1H-Imidazo[4,5-c]quinoline,;IMiquiMod Related CoMpound C;Imiquimod USP Related Compound C;4-Chloro-1-isobutyl-1H-imidazo[4,5-;1H-IMIDAZO[4,5-C]QUINOLINE, 4-CHLORO-1-(;4-CHLORO-1-ISOBUTYL-1H-IMIBENZO(4,5-C)QUINOLINE
- CBNumber:
- CB6449735
- Molecular Formula:
- C14H14ClN3
- Molecular Weight:
- 259.73
- MDL Number:
- MFCD06658174
- MOL File:
- 99010-64-7.mol
Melting point | 139-140 °C(Solv: isopropanol (67-63-0)) |
---|---|
Boiling point | 427.5±48.0 °C(Predicted) |
Density | 1.29±0.1 g/cm3(Predicted) |
storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
solubility | Chloroform (Sparingly), Methanol (Slightly) |
form | Solid |
pka | 3.15±0.30(Predicted) |
color | White to Off-White |
CAS DataBase Reference | 99010-64-7(CAS DataBase Reference) |
FDA UNII | NJ5E4GY4NY |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS07 |
---|---|
Signal word | Warning |
Hazard statements | H302-H315-H319-H335 |
Precautionary statements | P261-P305+P351+P338 |
HS Code | 2934990002 |
4-Chloro-1-(2-methylpropyl)-1H-imidazo[4,5-c]quinoline price More Price(8)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | 1338346 | Imiquimod Related Compound C United States Pharmacopeia (USP) Reference Standard | 99010-64-7 | 25MG | $1230 | 2022-05-15 | Buy |
Usbiological | 446210 | Desamino Chloroimiquimod | 99010-64-7 | 5mg | $460 | 2021-12-16 | Buy |
TRC | D288295 | DesaminoChloroimiquimod | 99010-64-7 | 5mg | $185 | 2021-12-16 | Buy |
AK Scientific | S437 | 4-Chloro-1-(2-methylpropyl)-1H-imidazo[4,5-c]quinoline | 99010-64-7 | 10g | $49 | 2021-12-16 | Buy |
AK Scientific | S437 | 4-Chloro-1-(2-methylpropyl)-1H-imidazo[4,5-c]quinoline | 99010-64-7 | 25g | $100 | 2021-12-16 | Buy |
4-Chloro-1-(2-methylpropyl)-1H-imidazo[4,5-c]quinoline Chemical Properties,Uses,Production
Description
4-Chloro-1-(2-methylpropyl)-1H-imidazo[4,5-c]quinoline is a chemical product that has been used as a photosynthetic activator in weed science and pest control. It has been shown to significantly increase the growth rate of wheat, soybean, and oilseed crops. It is also effective at controlling weeds by inhibiting their ability to produce chlorophyll, thereby preventing them from photosynthesizing. 4-Chloro-1-(2-methylpropyl)-1H-imidazo[4,5-c]quinoline has also been shown to be an effective herbicide for agricultural use.
Uses
Desamino Chloroimiquimod (Imiquimod USP Related Compound C) is a pharmacologically active compound related to Imiquimod (I475000), an immune response modifier. It stimulates the production of Interferon-a.
Synthesis
4-Chloro-1-(2-methylpropyl)-1H-imidazo[4,5-c]quinoline is prepared by the reaction of 2-chloro-N4-(2-methylpropyl)quinoline-3,4-diamine and orthoformic acid triethyl ester. The specific synthesis steps are as follows:
A suspension of 2-chloro-N4 -(2-methylpropyl)-3,4-quinolinediamine (35 g) and triethylorthoformate (52.3 g, 2.5 eq) was heated at 145° C. for 10 h, during which time ethanol was removed by distillation. The resulting mixture was cooled to room temperature and the solid was removed by filtration. The solid was dissolved in hydrochloric acid (100 mL, 4N). The resulting solution was added to a solution of sodium hydroxide. The precipitate was filtered and washed with water to afford the product 4-chloro-1-(2-methylpropyl)-1H-imidazo[4,5-c]quinoline in 92% yield.
4-Chloro-1-(2-methylpropyl)-1H-imidazo[4,5-c]quinoline Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Capot Chemical Co.,Ltd. | +86-(0)57185586718 +86-13336195806 | sales@capot.com | China | 29791 | 60 |
Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 | info@dakenam.com | China | 18754 | 58 |
Beijing Cooperate Pharmaceutical Co.,Ltd | 010-60279497 | sales01@cooperate-pharm.com | CHINA | 1803 | 55 |
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21637 | 55 |
Hangzhou FandaChem Co.,Ltd. | +8615858145714 | FandaChem@Gmail.com | China | 9215 | 55 |
Shanxi Naipu Import and Export Co.,Ltd | +86-13734021967 +8613734021967 | kaia@neputrading.com | China | 1001 | 58 |
career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29885 | 58 |
NINGBO INNO PHARMCHEM CO., LTD. | 13867897135 | sales@nbinno.com | CHINA | 923 | 58 |
Shanghai Arbor Chemical Co., Ltd. | 021-60451682 | act@arborchemical.com | CHINA | 904 | 58 |
Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 | admin@nexconn.com | China | 10310 | 58 |
View Lastest Price from 4-Chloro-1-(2-methylpropyl)-1H-imidazo[4,5-c]quinoline manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2022-04-14 | 4-chloro-1-(2-methylpropyl)-1h-imidazo(4,5-c)quinoline
99010-64-7
|
US $80.00 / bag | 1bag | 99 | 500 | Shanxi Naipu Import and Export Co.,Ltd | ||
2019-07-06 | 4-Chloro-1-(2-methylpropyl)-1H-imidazo[4,5-c]quinoline
99010-64-7
|
US $1.00 / KG | 1KG | 90%-99.99% | 1000kgs | Career Henan Chemical Co |
- 4-chloro-1-(2-methylpropyl)-1h-imidazo(4,5-c)quinoline
99010-64-7
- US $80.00 / bag
- 99
- Shanxi Naipu Import and Export Co.,Ltd
- 4-Chloro-1-(2-methylpropyl)-1H-imidazo[4,5-c]quinoline
99010-64-7
- US $1.00 / KG
- 90%-99.99%
- Career Henan Chemical Co
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