ChemicalBook >> CAS DataBase List >>6-[1-(3,5,5,8,8-PENTAMETHYL-5,6,7,8-TETRAHYDRO-NAPHTHALEN-2-YL)-CYCLOPROPYL]-NICOTINIC ACID

6-[1-(3,5,5,8,8-PENTAMETHYL-5,6,7,8-TETRAHYDRO-NAPHTHALEN-2-YL)-CYCLOPROPYL]-NICOTINIC ACID

CAS No.
153559-76-3
Chemical Name:
6-[1-(3,5,5,8,8-PENTAMETHYL-5,6,7,8-TETRAHYDRO-NAPHTHALEN-2-YL)-CYCLOPROPYL]-NICOTINIC ACID
Synonyms
LG 268;CD 3127;lg100268;ALRT 268;LGD 1268;AGN 192620;LGD 100268;hthalenyl)cyclopropyl)-;3-pyridinecarboxylicacid,6-(1-(5,6,7,8-tetrahydro-3,5,5,8,8-pentamethyl-2-nap;6-[1-(3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydro-2-naphthyl)cyclopropyl]nicotinic Acid
CBNumber:
CB6458625
Molecular Formula:
C24H29NO2
Molecular Weight:
363.49
MDL Number:
MFCD01758574
MOL File:
153559-76-3.mol
MSDS File:
SDS
Last updated:2023-06-30 15:45:59

6-[1-(3,5,5,8,8-PENTAMETHYL-5,6,7,8-TETRAHYDRO-NAPHTHALEN-2-YL)-CYCLOPROPYL]-NICOTINIC ACID Properties

Melting point 275-277°C
Boiling point 487.0±33.0 °C(Predicted)
Density 1.115±0.06 g/cm3(Predicted)
storage temp. -20°C
solubility DMSO: ≥5mg/mL (warmed)
pka 2.35±0.10(Predicted)
form powder
color white to beige
FDA UNII UVU4X1103P

SAFETY

Risk and Safety Statements

WGK Germany  3

6-[1-(3,5,5,8,8-PENTAMETHYL-5,6,7,8-TETRAHYDRO-NAPHTHALEN-2-YL)-CYCLOPROPYL]-NICOTINIC ACID price More Price(18)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich SML0279 LG100268 ≥98% (HPLC) 153559-76-3 5mg $144 2024-03-01 Buy
Sigma-Aldrich SML0279 LG100268 ≥98% (HPLC) 153559-76-3 25mg $568 2024-03-01 Buy
Cayman Chemical 21606 LG 100268 ≥98% 153559-76-3 1mg $44 2024-03-01 Buy
Cayman Chemical 21606 LG 100268 ≥98% 153559-76-3 5mg $118 2024-03-01 Buy
Cayman Chemical 21606 LG 100268 ≥98% 153559-76-3 10mg $214 2024-03-01 Buy
Product number Packaging Price Buy
SML0279 5mg $144 Buy
SML0279 25mg $568 Buy
21606 1mg $44 Buy
21606 5mg $118 Buy
21606 10mg $214 Buy

6-[1-(3,5,5,8,8-PENTAMETHYL-5,6,7,8-TETRAHYDRO-NAPHTHALEN-2-YL)-CYCLOPROPYL]-NICOTINIC ACID Chemical Properties,Uses,Production

Chemical Properties

Off-White Solid

Uses

LG 100268 is a potent RXR agonist for evaluation in the treatment of non-insulin-dependent (type II) diabetes mellitus (NIDDM).

Biochem/physiol Actions

LG100268 (LG268) is a potent and selective rexinoid and retinoid-X receptor (RXR) agonist. LG100268 binds to the α, β and γ RXR receptors with an IC50 = 3-4 nM and has no activity at the RAR retinoic acid receptors.

storage

Store at -20°C

6-[1-(3,5,5,8,8-PENTAMETHYL-5,6,7,8-TETRAHYDRO-NAPHTHALEN-2-YL)-CYCLOPROPYL]-NICOTINIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

6-[1-(3,5,5,8,8-PENTAMETHYL-5,6,7,8-TETRAHYDRO-NAPHTHALEN-2-YL)-CYCLOPROPYL]-NICOTINIC ACID Suppliers

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2-[1-(3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydro-2-naphthyl)cyclopropyl]pyridine-5-carboxylic acid 6-[1-(3,5,5,8,8-PENTAMETHYL-5,6,7,8-TETRAHYDRO-NAPHTHALEN-2-YL)-CYCLOPROPYL]-NICOTINIC ACID 6-[1-(3,5,5,8,8-PentaMethyl-5,6,7,8-tetrahydronaphthalen-2-yl)cyclopropyl]pyridine-3-carboxylic acid 3-Pyridinecarboxylicacid,6-[1-(5,6,7,8-tetrahydro-3,5,5,8,8-pentaMethyl-2-naphthalenyl)cyclopropyl]- 3-pyridinecarboxylicacid,6-(1-(5,6,7,8-tetrahydro-3,5,5,8,8-pentamethyl-2-nap hthalenyl)cyclopropyl)- lg100268 6-[1-(3,5,5,8,8-PENTAMETHYL-5,6,7,8-TETRAHYDRO-NAPHTHALEN-2-YL)-CYCLOPROPYL]-NICOTINIC ACID (FOR R&D ONLY) 6-[1-(5,6,7,8-tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)cyclopropyl]- 3-Pyridinecarboxylic Acid AGN 192620 ALRT 268 CD 3127 LG 268 LGD 100268 LGD 1268 6-[1-(3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydro-2-naphthyl)cyclopropyl]nicotinic Acid 153559-76-3 Intermediates & Fine Chemicals Pharmaceuticals Retinoids