4,5-Dimethyl-3-hydroxy-2,5-dihydrofuran-2-one
- CAS No.
- 28664-35-9
- Chemical Name:
- 4,5-Dimethyl-3-hydroxy-2,5-dihydrofuran-2-one
- Synonyms
- SOTOLON;3-hydroxy-4,5-dimethylfuran-2(5H)-one;3-HYDROXY-4,5-DIMETHYL-2(5H)-FURANONE;SOTOLONE;SUGAR LACTONE;CARAMEL FURANONE;FENUGREEK LACTONE;3-hydroxy-4,5-dimethyl-2(5H)-furanone (sotolon);FEMA 3634;3-hydroxy-4,5-dimethyl-2(5h)-furanon
- CBNumber:
- CB6466523
- Molecular Formula:
- C6H8O3
- Molecular Weight:
- 128.13
- MDL Number:
- MFCD00059957
- MOL File:
- 28664-35-9.mol
- MSDS File:
- SDS
Melting point | 26-29 °C(lit.) |
---|---|
Boiling point | 184 °C(lit.) |
Density | 1.049 g/mL at 25 °C |
refractive index |
n |
FEMA | 3634 | 4,5-DIMETHYL-3-HYDROXY-2,5-DIHYDROFURAN-2-ONE |
Flash point | >230 °F |
storage temp. | Sealed in dry,2-8°C |
pka | 9.28±0.40(Predicted) |
Odor | at 0.01 % in propylene glycol. extremely sweet strong caramel maple burnt sugar coffee |
Odor Type | caramellic |
JECFA Number | 243 |
InChIKey | UNYNVICDCJHOPO-UHFFFAOYSA-N |
LogP | -0.44 |
CAS DataBase Reference | 28664-35-9(CAS DataBase Reference) |
Substances Added to Food (formerly EAFUS) | 4,5-DIMETHYL-3-HYDROXY-2,5-DIHYDROFURAN-2-ONE |
EWG's Food Scores | 1 |
FDA UNII | T62RL2NEGW |
NIST Chemistry Reference | 2(5H)-furanone, 3-hydroxy-4,5-dimethyl-(28664-35-9) |
EPA Substance Registry System | 2(5H)-Furanone, 3-hydroxy-4,5-dimethyl- (28664-35-9) |
4,5-Dimethyl-3-hydroxy-2,5-dihydrofuran-2-one price More Price(42)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | W363499 | 4,5-Dimethyl-3-hydroxy-2,5-dihydrofuran-2-one natural, ≥97%, FG | 28664-35-9 | SAMPLE-K | $220 | 2024-03-01 | Buy |
Sigma-Aldrich | W363499 | 4,5-Dimethyl-3-hydroxy-2,5-dihydrofuran-2-one natural, ≥97%, FG | 28664-35-9 | 25G | $292 | 2024-03-01 | Buy |
Sigma-Aldrich | W363499 | 4,5-Dimethyl-3-hydroxy-2,5-dihydrofuran-2-one natural, ≥97%, FG | 28664-35-9 | 100G | $819 | 2024-03-01 | Buy |
Sigma-Aldrich | W363421 | 4,5-Dimethyl-3-hydroxy-2,5-dihydrofuran-2-one solution 3?wt. % in propylene glycol | 28664-35-9 | 100g | $106 | 2024-03-01 | Buy |
Sigma-Aldrich | W363421 | 4,5-Dimethyl-3-hydroxy-2,5-dihydrofuran-2-one solution 3?wt. % in propylene glycol | 28664-35-9 | 1kg | $513 | 2024-03-01 | Buy |
4,5-Dimethyl-3-hydroxy-2,5-dihydrofuran-2-one Chemical Properties,Uses,Production
Chemical Properties
3-Hydroxy-4,5-dimethyl-2(5H)-furanone was found in, for example, fenugreek, coffee, sake, and florsherry. Its aroma characteristic changes from caramel-like at low concentrations to curry-like at high concentrations. A method described for its preparation comprises condensation of ethyl propionate with diethyl oxalate and reaction of the intermediately formed diethyl oxalylpropionate with acetaldehyde. Acidic decarboxylation of the ethyl 4,5-dimethyl-2,3-dioxodihydrofuran-4-carboxylate gives the title compound.
Chemical Properties
clear yellow liquid
Occurrence
Reported found in roasted Virginia tobacco, beef broth, beer, sherry, botryized wine, coffee, tea, fenugreek, sake and rice wine.
Uses
4,5-Dimethyl-3-hydroxy-2(5H)-furanone-13C3 is a labelled analogue of 4,5-Dimethyl-3-hydroxy-2(5H)-furanone (D473600). 4,5-Dimethyl-3-hydroxy-2(5H)-furanone is a fragrant compound that is a key indicator of maple syrup urine disease, a disorder affecting newborn children that is the result of its inability to properly metabolize Valine (V094205), Leucine (L330110) and Isoleucine (I820175). 4,5-Dimethyl-3-hydroxy-2(5H)-furanone is naturally found in fenugreek seeds, and is an odourant present in sherry wines.
Definition
ChEBI: Sotolone is a butenolide. It has a role as a metabolite.
Aroma threshold values
Aroma characteristics at 1.0%; sweet, strong brown, cyclotene and maple like, caramel, toffee, maltol-like and burnt, brown sugar fenugreek-like, cooked and syrupy.
Taste threshold values
Taste characteristics at 5–25 ppm; sweet, caramel, maple, walnut, brown sugar, nutty, cotton candy, fenugreek and celery-like, rum, roasted meaty with a honey nuance
4,5-Dimethyl-3-hydroxy-2,5-dihydrofuran-2-one Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Hebei Mojin Biotechnology Co., Ltd | +8613288715578 | sales@hbmojin.com | China | 12450 | 58 |
Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20294 | 58 |
Hebei Zhuanglai Chemical Trading Co.,Ltd | +8613343047651 | admin@zlchemi.com | China | 3002 | 58 |
JINING XINHE CHEMICAL CO., LTD | +8615318402391 | sales@xinhepharma.com | China | 807 | 58 |
Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 | info@dakenam.com | China | 16914 | 58 |
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21668 | 55 |
career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29894 | 58 |
Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
Xiamen AmoyChem Co., Ltd | +86-592-6051114 +8618959220845 | sales@amoychem.com | China | 6387 | 58 |
Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22968 | 58 |
View Lastest Price from 4,5-Dimethyl-3-hydroxy-2,5-dihydrofuran-2-one manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
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2024-07-18 | 4,5-Dimethyl-3-hydroxy-2,5-dihydrofuran-2-one
28664-35-9
|
US $0.00-0.00 / kg | 1kg | 99% | 10ton | JINING XINHE CHEMICAL CO., LTD | |
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2024-05-27 | 4,5-Dimethyl-3-hydroxy-2,5-dihydrofuran-2-one
28664-35-9
|
US $75.00-25.00 / kg | 1kg | 99% | 20ton | Hebei Zhuanglai Chemical Trading Co.,Ltd | |
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2024-03-28 | Sugar lactone
28664-35-9
|
US $0.00 / KG | 25KG | 97% | Inquiry | PNP Biotech Co. Ltd |
-
- 4,5-Dimethyl-3-hydroxy-2,5-dihydrofuran-2-one
28664-35-9
- US $0.00-0.00 / kg
- 99%
- JINING XINHE CHEMICAL CO., LTD
-
- 4,5-Dimethyl-3-hydroxy-2,5-dihydrofuran-2-one
28664-35-9
- US $75.00-25.00 / kg
- 99%
- Hebei Zhuanglai Chemical Trading Co.,Ltd
-
- Sugar lactone
28664-35-9
- US $0.00 / KG
- 97%
- PNP Biotech Co. Ltd