RP 001 (hydrochloride)
- CAS No.
- 1781880-34-9
- Chemical Name:
- RP 001 (hydrochloride)
- Synonyms
- RP001 hydrochloride,RP 001 hydrochloride;N-[4-[5-[3-cyano-4-(1-methylethoxy)phenyl]-1,2,4-oxadiazol-3-yl]-2,3-dihydro-1H-inden-1-yl]-β-alanine,monohydrochloride
- CBNumber:
- CB64666596
- Molecular Formula:
- C24H25ClN4O4
- Molecular Weight:
- 468.94
- MDL Number:
- MOL File:
- 1781880-34-9.mol
RP 001 (hydrochloride) price More Price(7)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 16636 | RP 001 (hydrochloride) ≥98% | 1781880-34-9 | 1mg | $37 | 2024-03-01 | Buy |
| Cayman Chemical | 16636 | RP 001 (hydrochloride) ≥98% | 1781880-34-9 | 5mg | $161 | 2024-03-01 | Buy |
| Cayman Chemical | 16636 | RP 001 (hydrochloride) ≥98% | 1781880-34-9 | 10mg | $249 | 2024-03-01 | Buy |
| Cayman Chemical | 16636 | RP 001 (hydrochloride) ≥98% | 1781880-34-9 | 25mg | $530 | 2024-03-01 | Buy |
| TRC | R700988 | RP001Hydrochloride | 1781880-34-9 | 50mg | $975 | 2021-12-16 | Buy |
RP 001 (hydrochloride) Chemical Properties,Uses,Production
Description
RP 001 is a potent sphingosine-1-phosphate receptor 1 (S1P1) agonist (EC50 = 9 pM). It is competitive with W146 , a selective S1P1 antagonist, and induces internalization and polyubiquitination of S1P1 in a dose-dependent manner. RP 001 induces dose-dependent lymphopenia in mice (EC50 = 0.03 mg/kg). It reduces S1P1-EGFP expression ex vivo on lymphocytes in the isolated lymph node of Edg1eGFP/eGFP mice but has no effect in vivo. RP 001 also completely inhibits M. stadtmanae (MSS) rechallenge-induced enlargement of B cell-rich tertiary lymphoid tissues (TLTs) and reduces neutrophil accumulation in the airways of a mouse model of experimental hypersensitivity pneumonitis.
Uses
RP 001 Hydrochloride is a picomolar, short-acting S1P1 agonist.
storage
Store at -20°C
RP 001 (hydrochloride) Preparation Products And Raw materials
Raw materials
Preparation Products
RP 001 (hydrochloride) Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| Aladdin Scientific | +1-+1(833)-552-7181 | sales@aladdinsci.com | United States | 52927 | 58 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9707 | 58 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11289 | 58 |
| Changzhou Furuisi Biotechnology Co., Ltd | 0519-85524369 | 3477467573@qq.com | China | 8618 | 58 |
| TargetMol Chemicals Inc. | 4008200310 | marketing@tsbiochem.com | China | 24017 | 58 |