RP 001 (hydrochloride)

 化学構造式
1781880-34-9
CAS番号.
1781880-34-9
化学名:
别名:
英語名:
RP 001 (hydrochloride)
英語别名:
RP001 hydrochloride,RP 001 hydrochloride;N-[4-[5-[3-cyano-4-(1-methylethoxy)phenyl]-1,2,4-oxadiazol-3-yl]-2,3-dihydro-1H-inden-1-yl]-β-alanine,monohydrochloride
CBNumber:
CB64666596
化学式:
C24H25ClN4O4
分子量:
468.94
MOL File:
1781880-34-9.mol

RP 001 (hydrochloride) 物理性質

貯蔵温度 :
Store at -20°C
溶解性:
DMSO: 100 mM
外見 :
A solid

安全性情報

RP 001 (hydrochloride) 価格 もっと(2)

メーカー 製品番号 製品説明 CAS番号 包装 価格 更新時間 購入
富士フイルム和光純薬株式会社(wako) W01TOC4289
RP 001 hydrochloride
1781880-34-9 10mg ¥90000 2024-03-01 購入
富士フイルム和光純薬株式会社(wako) W01TOC4289
RP 001 hydrochloride
1781880-34-9 50mg ¥372000 2024-03-01 購入

RP 001 (hydrochloride) 化学特性,用途語,生産方法

説明

RP 001 is a potent sphingosine-1-phosphate receptor 1 (S1P1) agonist (EC50 = 9 pM). It is competitive with W146 , a selective S1P1 antagonist, and induces internalization and polyubiquitination of S1P1 in a dose-dependent manner. RP 001 induces dose-dependent lymphopenia in mice (EC50 = 0.03 mg/kg). It reduces S1P1-EGFP expression ex vivo on lymphocytes in the isolated lymph node of Edg1eGFP/eGFP mice but has no effect in vivo. RP 001 also completely inhibits M. stadtmanae (MSS) rechallenge-induced enlargement of B cell-rich tertiary lymphoid tissues (TLTs) and reduces neutrophil accumulation in the airways of a mouse model of experimental hypersensitivity pneumonitis.

使用

RP 001 Hydrochloride is a picomolar, short-acting S1P1 agonist.

RP 001 (hydrochloride) 上流と下流の製品情報

原材料

準備製品


RP 001 (hydrochloride) 生産企業

Global( 9)Suppliers
名前 電話番号 電子メール 国籍 製品カタログ 優位度
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000
marketing@targetmol.com United States 32076 58
TargetMol Chemicals Inc.

support@targetmol.com United States 38468 58
Aladdin Scientific
+1-+1(833)-552-7181
sales@aladdinsci.com United States 52925 58
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627
info@efebio.com China 9806 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767
sales@chemegen.com China 11217 58
Changzhou Furuisi Biotechnology Co., Ltd 0519-85524369
3477467573@qq.com China 8617 58
TargetMol Chemicals Inc. 15002134094
marketing@targetmol.cn China 19711 58

  • 1781880-34-9
  • RP001 hydrochloride,RP 001 hydrochloride
  • N-[4-[5-[3-cyano-4-(1-methylethoxy)phenyl]-1,2,4-oxadiazol-3-yl]-2,3-dihydro-1H-inden-1-yl]-β-alanine,monohydrochloride
Copyright 2017 © ChemicalBook. All rights reserved