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PSI-7977-13C-d3

CAS No.
2070009-25-3
Chemical Name:
PSI-7977-13C-d3
Synonyms
PSI-7977-13C-d3;[13C,2H3]-Sofosbuvir;isopropyl((S)-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-(methyl-13C-d3)tetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)-L-alaninate;Sofosbuvir 13CD3Q: What is Sofosbuvir 13CD3 Q: What is the CAS Number of Sofosbuvir 13CD3 Q: What is the storage condition of Sofosbuvir 13CD3 Q: What are the applications of Sofosbuvir 13CD3
CBNumber:
CB64666758
Molecular Formula:
C2113CH26D3FN3O9P
Molecular Weight:
0
MDL Number:
MOL File:
Mol file
Last updated:2023-05-21 10:59:17

PSI-7977-13C-d3 Properties

storage temp. Store at -20°C
solubility DMF: 20 mg/ml,DMSO: 20 mg/ml,Ethanol: 25 mg/ml,PBS (pH 7.2): 0.2 mg/ml
form A solid

PSI-7977-13C-d3 price More Price(5)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 25045 PSI-7977-13C-d3 ≥99% deuterated forms (d1-d3) 2070009-25-3 1mg $456 2024-03-01 Buy
Usbiological 463192 PSI-7977-13CD3 2070009-25-3 1mg $531 2021-12-16 Buy
TRC P839642 PSI-7977-13CD3 2070009-25-3 1mg $220 2021-12-16 Buy
Medical Isotopes, Inc. 52859 PSI-7977-13CD3 2070009-25-3 1mg $700 2021-12-16 Buy
Medical Isotopes, Inc. 52859 PSI-7977-13CD3 2070009-25-3 10mg $2600 2021-12-16 Buy
Product number Packaging Price Buy
25045 1mg $456 Buy
463192 1mg $531 Buy
P839642 1mg $220 Buy
52859 1mg $700 Buy
52859 10mg $2600 Buy

PSI-7977-13C-d3 Chemical Properties,Uses,Production

Description

PSI-7977-13C-d3 is intended for use as an internal standard for the quantification of PSI-7977 by GC- or LC-MS. PSI-7977 is a phosphoramidate prodrug of PSI-7851, a nucleoside analog that, when phosphorylated, inhibits the RNA-dependent RNA polymerase of hepatitis C virus (EC50 = 92 nM). PSI-7977 is effective in vitro and in vivo.

Uses

PSI-7977-13CD3 is the isotope labelled analog of PSI-7977. PSI-7977 is a prodrug that is metabolized to the active antiviral agent 2''-deoxy-2''-α-fluoro-β-C-methyluridine-5''-monophosphate and is currently being investigated in phase 3 clinical trials for the treatment of hepatitis C. Studies have profiled PSI-7977 as a nucleotide inhibitor of hepatitis C virus, exerting selective inhibitory effects towards HCV NS5B polymerase.

PSI-7977-13C-d3 Preparation Products And Raw materials

Raw materials

Preparation Products

PSI-7977-13C-d3 Suppliers

Global( 16)Suppliers
Supplier Tel Email Country ProdList Advantage
ANHUI WITOP BIOTECH CO., LTD
+8615255079626 eric@witopchemical.com China 23541 58
Shanghai Payne Pharmaceutical Technology Co.Ltd
021-58123769 18678586262 info@paynepharm.com China 1354 58
Artis Biotech Co. Ltd. 0575-18780151478 18582380095 sales@artisbio.com China 2964 58
Shanghai Payne Pharmaceutical Technology Co.Ltd 021-58123769 17721400256 info@paynepharm.com China 1285 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11217 58
PureChemland Co.,Ltd. 18581895003 18084815636 3848291069@qq.com China 3594 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 11974 58
Nanjing Shizhou Biology Technology Co.,Ltd 17301488900 judy.xia@synzest.com China 12582 58
Hubei Moco Chemical Co., Ltd. 18627753421 18576690171 3001009495@qq.com China 11112 58
United States Biological -- sales@advtechind.com United States 6075 58
[13C,2H3]-Sofosbuvir isopropyl((S)-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-(methyl-13C-d3)tetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)-L-alaninate Sofosbuvir 13CD3Q: What is Sofosbuvir 13CD3 Q: What is the CAS Number of Sofosbuvir 13CD3 Q: What is the storage condition of Sofosbuvir 13CD3 Q: What are the applications of Sofosbuvir 13CD3 PSI-7977-13C-d3 2070009-25-3 C2113CH26D3FN3O9P