PSI-7977-13C-d3

2070009-25-3

CAS番号.: 2070009-25-3

化学名:

别名:

英語名:: PSI-7977-13C-d3

英語别名:: [13C,2H3]-Sofosbuvir;isopropyl((S)-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-(methyl-13C-d3)tetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)-L-alaninate;Sofosbuvir 13CD3Q: What is Sofosbuvir 13CD3 Q: What is the CAS Number of Sofosbuvir 13CD3 Q: What is the storage condition of Sofosbuvir 13CD3 Q: What are the applications of Sofosbuvir 13CD3

CBNumber:: CB64666758

化学式:: C2113CH26D3FN3O9P

分子量:: 0

MOL File:: Mol file

物理性質

安全性情報

用途語

生産企業 15

PSI-7977-13C-d3 物理性質

貯蔵温度 :: Store at -20°C

溶解性:: DMF: 20 mg/ml,DMSO: 20 mg/ml,Ethanol: 25 mg/ml,PBS (pH 7.2): 0.2 mg/ml

外見 :: A solid

安全性情報

PSI-7977-13C-d3 価格

メーカー	製品番号	製品説明	CAS番号	包装	価格	更新時間	購入

PSI-7977-13C-d3 化学特性,用途語,生産方法

説明

PSI-7977-¹³C-d₃ is intended for use as an internal standard for the quantification of PSI-7977 by GC- or LC-MS. PSI-7977 is a phosphoramidate prodrug of PSI-7851, a nucleoside analog that, when phosphorylated, inhibits the RNA-dependent RNA polymerase of hepatitis C virus (EC₅₀ = 92 nM). PSI-7977 is effective in vitro and in vivo.

使用

PSI-7977-13CD3 is the isotope labelled analog of PSI-7977. PSI-7977 is a prodrug that is metabolized to the active antiviral agent 2''-deoxy-2''-α-fluoro-β-C-methyluridine-5''-monophosphate and is currently being investigated in phase 3 clinical trials for the treatment of hepatitis C. Studies have profiled PSI-7977 as a nucleotide inhibitor of hepatitis C virus, exerting selective inhibitory effects towards HCV NS5B polymerase.

PSI-7977-13C-d3 上流と下流の製品情報

原材料

準備製品

PSI-7977-13C-d3 生産企業

Global( 15)Suppliers

名前	電話番号	電子メール	国籍	製品カタログ	優位度
ANHUI WITOP BIOTECH CO., LTD	+8615255079626	eric@witopchemical.com	China	23556	58
Shanghai Payne Pharmaceutical Technology Co.Ltd	021-58123769 18678586262	info@paynepharm.com	China	1354	58
Artis Biotech Co. Ltd.	19138486554 18582380095	sales@artisbio.com	China	2754	58
Shanghai Payne Pharmaceutical Technology Co.Ltd	021-58123769 17721400256	info@paynepharm.com	China	1285	58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.	18818260767	sales@chemegen.com	China	11289	58
Shanghai Yifei Biotechnology Co. , Ltd.	021-65675885 18964387627	customer_service@efebio.com	China	8739	58
Nanjing Shizhou Biology Technology Co.,Ltd	17301488900	judy.xia@synzest.com	China	12584	58
Hubei Moco Chemical Co., Ltd.	18627753421 18627756402	3001009495@qq.com	China	10954	58
United States Biological	--	sales@advtechind.com	United States	6106	58

2070009-25-3()キーワード:

ソホスブビル (2'R)-N-ベンゾイル-2'-デオキシ-2'-フルオロ-2'-メチルシチジン3',5'-二安息香酸

2070009-25-3
[13C,2H3]-Sofosbuvir
isopropyl((S)-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-(methyl-13C-d3)tetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)-L-alaninate
Sofosbuvir 13CD3Q: What is Sofosbuvir 13CD3 Q: What is the CAS Number of Sofosbuvir 13CD3 Q: What is the storage condition of Sofosbuvir 13CD3 Q: What are the applications of Sofosbuvir 13CD3