Neuromedin B (trifluoroacetate salt)
- CAS No.
- Chemical Name:
- Neuromedin B (trifluoroacetate salt)
- Synonyms
- Neuromedin B (trifluoroacetate salt)
- CBNumber:
- CB64667038
- Molecular Formula:
- C52H73N15O12S
- Molecular Weight:
- 1132.29432
- MDL Number:
- MOL File:
- Mol file
Neuromedin B (trifluoroacetate salt) price More Price(1)
Neuromedin B (trifluoroacetate salt) Chemical Properties,Uses,Production
Description
Neuromedin B (NMB) is a peptide agonist of the NMB receptor (Ki = 7.4 nM in NCI-H1299 small cell lung cancer cells expressing the human receptor). It displays similar affinity for frog [Phe13]bombesin receptors (Ki = 11 nM) and lower affinities for human gastrin-releasing peptide receptor and bombesin receptor subtype 3 (Kis = 440 and 4,800 nM, respectively). Intrathecal administration of NMB (0.1-1 nmol) induces dose-dependent itching behavior in mice. NMB (50 μg, s.c.) reduces serum thyroid stimulating hormone (TSH) by 30% in mice indicating a role in pituitary-thyroid axis function. In rodents, NMB is also involved in mediating stress and fear responses, thermoregulation, and can stimulate the contraction of the uterus and gastrointestinal smooth muscle.
Neuromedin B (trifluoroacetate salt) Preparation Products And Raw materials
Raw materials
Preparation Products
Neuromedin B (trifluoroacetate salt) Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Shanghai Hongye Biotechnology Co. Ltd | 400-9205774 | sales@glpbio.cn | China | 6870 | 58 |
ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11289 | 58 |
Supplier | Advantage |
---|---|
Shanghai Hongye Biotechnology Co. Ltd | 58 |
ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 58 |