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JTZ-951

CAS No.
1262132-81-9
Chemical Name:
JTZ-951
Synonyms
JTZ-951;Enarodustat;enarodustat(JTZ-951);JTZ-951(Enarodustat);(7-hydroxy-5-phenethyl[1,2,4]triazolo[1,5-a]pyridine-8-carbonyl)glycine;2-(7-Hydroxy-5-phenethyl-[1,2,4]triazolo[1,5-a]pyridine-8-carboxamido)acetic acid;Glycine, N-[[7-hydroxy-5-(2-phenylethyl)[1,2,4]triazolo[1,5-a]pyridin-8-yl]carbonyl]-;HIF/HIF Prolyl-Hydroxylase,HIFs,inhibit,JTZ951,HIF-PH,Hypoxia-inducible factors,JTZ 951,Enarodustat,Inhibitor
CBNumber:
CB64668095
Molecular Formula:
C17H16N4O4
Molecular Weight:
340.33
MDL Number:
MFCD31692356
MOL File:
1262132-81-9.mol
Last updated:2024-07-02 08:55:14

JTZ-951 Properties

Density 1.44±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMSO:60.44(Max Conc. mg/mL);177.59(Max Conc. mM)
DMSO:PBS (pH 7.2) (1:4):0.2(Max Conc. mg/mL);0.59(Max Conc. mM)
DMF:30.0(Max Conc. mg/mL);88.15(Max Conc. mM)
Ethanol:25.0(Max Conc. mg/mL);73.46(Max Conc. mM)
form A solid
pka 0.58±0.53(Predicted)
color White to off-white
FDA UNII JSK7TUA223

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P280-P305+P351+P338
NFPA 704
0
2 0

JTZ-951 price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
ChemScene CS-0031647 Enarodustat 98.01% 1262132-81-9 5mg $85 2021-12-16 Buy
ChemScene CS-0031647 Enarodustat 98.01% 1262132-81-9 10mg $140 2021-12-16 Buy
ChemScene CS-0031647 Enarodustat 98.01% 1262132-81-9 50mg $400 2021-12-16 Buy
ChemScene CS-0031647 Enarodustat 98.01% 1262132-81-9 100mg $750 2021-12-16 Buy
Alichem 1262132819 (7-Hydroxy-5-phenethyl-[1,2,4]triazolo[1,5-a]pyridine-8-carbonyl)glycine 1262132-81-9 250mg $930 2021-12-16 Buy
Product number Packaging Price Buy
CS-0031647 5mg $85 Buy
CS-0031647 10mg $140 Buy
CS-0031647 50mg $400 Buy
CS-0031647 100mg $750 Buy
1262132819 250mg $930 Buy

JTZ-951 Chemical Properties,Uses,Production

Uses

Enarodustat is in the process of being approved for use in treating anemia associated with chronic kidney disease.

JTZ-951 Preparation Products And Raw materials

Raw materials

Preparation Products

JTZ-951 Suppliers

Global( 53)Suppliers
Supplier Tel Email Country ProdList Advantage
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795 ivan@atkchemical.com China 32760 60
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
HANGZHOU CLAP TECHNOLOGY CO.,LTD
86-571-88216897,88216896 13588875226 sales@hzclap.com CHINA 6313 58
Zhejiang J&C Biological Technology Co.,Limited
+1-2135480471 +1-2135480471 sales@sarms4muscle.com China 10522 58
InvivoChem
+1-708-310-1919 +1-13798911105 sales@invivochem.cn United States 6393 58
LEAP CHEM CO., LTD.
+86-852-30606658 market18@leapchem.com China 24738 58
Aladdin Scientific
+1-+1(833)-552-7181 sales@aladdinsci.com United States 57511 58
Wuhan Jingkang en Biomedical Technology Co., Ltd
+8613720134139 orders@jknbiochem.com China 4692 58
WUHAN SUN-SHINE BIO-TECHNOLOGY Co., Ltd. 17702719238 17702719238 sales@sun-shinechem.com China 923 64
Shanghai Topbiochem Technology Co., Ltd 021-58170097 info@topbiochem.com China 9461 58

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  • Synthesis of Enarodustat(JTZ-951)
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  • Dec 22,2023
JTZ-951 Enarodustat Glycine, N-[[7-hydroxy-5-(2-phenylethyl)[1,2,4]triazolo[1,5-a]pyridin-8-yl]carbonyl]- (7-hydroxy-5-phenethyl[1,2,4]triazolo[1,5-a]pyridine-8-carbonyl)glycine JTZ-951(Enarodustat) enarodustat(JTZ-951) HIF/HIF Prolyl-Hydroxylase,HIFs,inhibit,JTZ951,HIF-PH,Hypoxia-inducible factors,JTZ 951,Enarodustat,Inhibitor 2-(7-Hydroxy-5-phenethyl-[1,2,4]triazolo[1,5-a]pyridine-8-carboxamido)acetic acid 1262132-81-9