ChemicalBook >> CAS DataBase List >>Dolutegravir 2-Desfluoro Impurity
Dolutegravir 2-Desfluoro Impurity
- CAS No.
- 1863916-88-4
- Chemical Name:
- Dolutegravir 2-Desfluoro Impurity
- Synonyms
- 4-Fluoro Dolutegravir;Dolutegravir Impurity G;Dolutegravir Impurity 50;Dolutegravir Impurity 47;Dolutegravir 4-Fluoro Impurity;Dolutegravir 2-Desfluoro Impurity;(4R,12aS)-N-(4-fluorobenzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide;2H-Pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide, N-[(4-fluorophenyl)methyl]-3,4,6,8,12,12a-hexahydro-7-hydroxy-4-methyl-6,8-dioxo-, (4R,12aS)-;2H-Pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide, N-[(4-fluorophenyl)methyl]-3,4,6,8,12,12a-hexahydro-7-hydroxy-4-methyl-6,8-dioxo-, (4R,12aS)-/Dolutegravir impurity;Dolutegravir impurity 4/Defluoro Dolutegravir/(4R,12aS)-N-(4-Fluorobenzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide
- CBNumber:
- CB64796145
- Molecular Formula:
- C20H20FN3O5
- Molecular Weight:
- 401.39
- MDL Number:
- MOL File:
- 1863916-88-4.mol
Last updated:2023-07-12 17:02:14
Boiling point | 675.7±55.0 °C(Predicted) |
---|---|
Density | 1.49±0.1 g/cm3(Predicted) |
solubility | DMSO (Slightly), Methanol (Slightly, Heated) |
form | Solid |
pka | 4.50±1.00(Predicted) |
color | Off-White to Light Brown |
FDA UNII | CT8QT9HZN8 |
Dolutegravir 2-Desfluoro Impurity Chemical Properties,Uses,Production
Uses
Defluoro Dolutegravir is an impurity of Dolutegravir (D528800), a second generation HIV-1 integrase strand transfer inhibitor. Dolutegravir is currently in Phase III clinical trials for the treatment of HIV infection. Dolutegravir has been shown to potently inhibit HIV replication in cells such as peripheral blood mononuclear cells (PBMCs), MT-4 cells and CIP4 cells infected with a self-inactivating PHIV lentiviral vector.
Dolutegravir 2-Desfluoro Impurity Preparation Products And Raw materials
Raw materials
Preparation Products
Dolutegravir 2-Desfluoro Impurity Suppliers
Global( 32)Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
CR Corporation Lomited | fred.wen@crcorporation.cn | CHINA | 12069 | 58 | |
sgtlifesciences pvt ltd | +8617013299288 | dj@sgtlifesciences.com | China | 12382 | 58 |
China National Standard Pharmaceutical Corporation Limited | +8615391658522 | overseasales@yongstandards.com | China | 11927 | 58 |
ShenZhen H&D Pharmaceutical Technology Co., LTD | +86-0755-22677845 +86-13627253706 | sale@hdimpurity.com | China | 3389 | 58 |
Shenzhen Roark Pharma-Tec Co., Ltd. | 13128912434 | 2880126944@qq.com | China | 2579 | 58 |
Beijing Comparison Pharmaceutical Technology Co., Ltd | 010-010-52878169 15801002657 | sales@bjcomparison.com | China | 4805 | 58 |
ChemStrong Scientific Co.,Ltd | 0755-0755-66853366 13670046396 | sales@chem-strong.com | China | 18021 | 56 |
Shanghai CR Corporation Limited | 021-80270511; 4006653949 | fred.wen@crcorporation.cn | China | 10047 | 58 |
Guangzhou Jiuzhi Pharmaceutical Technology Co., Ltd. | 020-89854820 | sales@jzpharma.cn | China | 1082 | 58 |
Nanjing zehe Pharmaceutical Technology Co., Ltd | 17768115366 | henry124604479@163.com | China | 251 | 58 |
1863916-88-4(Dolutegravir 2-Desfluoro Impurity)Related Search:
2H-Pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide, N-[(4-fluorophenyl)methyl]-3,4,6,8,12,12a-hexahydro-7-hydroxy-4-methyl-6,8-dioxo-, (4R,12aS)-/Dolutegravir impurity
Dolutegravir impurity 4/Defluoro Dolutegravir/(4R,12aS)-N-(4-Fluorobenzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide
Dolutegravir Impurity G
Dolutegravir 2-Desfluoro Impurity
2H-Pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide, N-[(4-fluorophenyl)methyl]-3,4,6,8,12,12a-hexahydro-7-hydroxy-4-methyl-6,8-dioxo-, (4R,12aS)-
(4R,12aS)-N-(4-fluorobenzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide
Dolutegravir Impurity 47
Dolutegravir Impurity 50
4-Fluoro Dolutegravir
Dolutegravir 4-Fluoro Impurity
1863916-88-4